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The map label for this gene is ccoN [H]

Identifier: 227081614

GI number: 227081614

Start: 1495570

End: 1497003

Strand: Reverse

Name: ccoN [H]

Synonym: VCM66_1398

Alternate gene names: 227081614

Gene position: 1497003-1495570 (Counterclockwise)

Preceding gene: 227081618

Following gene: 227081613

Centisome position: 51.75

GC content: 47.63

Gene sequence:

>1434_bases
ATGCAAATGAGCCAAGAAAAGCAGCTTGAACAAAACTACAACTATACCGTGGTCCGCCAATTTACCCTGGTAACAATTCT
CTGGGGTATCGTCGGTATGGCTGTAGGGGTTTTGATTGCCGCTCAATTAGTTTGGCCACAGCTAAACTTTGATACGCCGT
GGTTGACGTACAGTCGCTTACGTCCTCTGCATACTAATGCGGTAATTTTTGCGTTTGGTACAAGTGCCCTGTTTGCAACA
TCATATTATGTTGTGCAGCGTACTTGCCAAACTCGTCTGTTCGGTGGACCGTTAGTTCCCTTTACCTTTTGGGGATGGCA
AGCGATTATCGTTTCCGCTGCAATCACCTTACCTTTGGGTTACACCTCAGGTAAAGAGTACGCAGAACTGGAATGGCCAA
TCGACATCGCCATCGCAGCGGTTTGGGTCGCTTATGCGGTTGTGTTCTTTGGAACCCTAGTAAAACGTAAAACATCTCAT
ATTTACGTGGCTAACTGGTTCTTCGGTGCCTTTATTATTACCGTTGCGGTATTGCACATTGTAAACAGTATGGCGCTCCC
CGTTTCGATGGGTAAGTCTTACTCTATCTACGCTGGTGCCGTCGATGCCATGGTGCAATGGTGGTATGGTCACAACGCTG
TAGGTTTCCTGCTCACGGCCGGCTTCCTAGGCATGATGTACTACTTTGTTCCTAAACAAGCTGAACGCCCAGTCTACTCT
TACCGTCTGTCTATCGTTCACTTTTGGGCTCTGATTTCTCTCTATATTTGGGCAGGTCCGCACCATTTGCATTACACCGC
ACTACCTGACTGGACTCAGTCTTTGGGCATGGTAATGTCTCTCGTGCTGTTCGCACCCTCTTGGGGTGGGATGATCAACG
GTATCATGACTCTTTCTGGTGCATGGCATAAGCTGCGCTATGATCCGATTCTTCGTTTCTTGATCGTTTCTCTGTCTTTC
TACGGCATGTCTACGTTTGAAGGCCCGATGATGTCAATCAAGACCGTCAATGCTTTATCCCACTACACCGACTGGACGAT
TGGTCACGTTCACTCTGGTGCGCTTGGTTGGGTAGCAATGGTGTCGATTGGTTCTGTTTACCATCTTATCCCACGTCTTT
TTGGACAAGAGCGCATGTACTCTGTCAGTCTGATCAACGCTCACTTCTGGTTAGCCACGATTGGTACAGTTCTGTACATC
GTTGCAATGTGGATCTCTGGCGTAATGCAAGGTTTGATGTGGCGTGCAGTGAACTCTGACGGCACACTGACATACAGCTT
TGTCGAGTCAGTGCAAGCGTCATATCCGTTCTATACCGTGCGTTTCATCGGTGGTTTCATCTTCTTGTCTGGGATGTTCC
TGATGGCTTACAACGCCTATAAGACCATTTCTGCACCTAAAAATAGCCTAAAAGCTATTGTGCAACCGGCATAA

Upstream 100 bases:

>100_bases
ATTAACAGTTTAGATGTCATTGTTTTTGTTGTGGATTTGGGTGGTGTTACGACGAAAGTCGTGTTGGAAGTAAAAGTGTA
GTTAATTAAACATTGGAAGC

Downstream 100 bases:

>100_bases
GGAGAATTAAGCAATGAGTTCTAATTCTAATAATCGCCATGAACTACTTGAGCGTAATGTCGGCTTACTGGCTATTTTCA
TTGTTTTTGCCATCAGTTGG

Product: cbb3-type cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome BB(3) subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MQMSQEKQLEQNYNYTVVRQFTLVTILWGIVGMAVGVLIAAQLVWPQLNFDTPWLTYSRLRPLHTNAVIFAFGTSALFAT
SYYVVQRTCQTRLFGGPLVPFTFWGWQAIIVSAAITLPLGYTSGKEYAELEWPIDIAIAAVWVAYAVVFFGTLVKRKTSH
IYVANWFFGAFIITVAVLHIVNSMALPVSMGKSYSIYAGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYS
YRLSIVHFWALISLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAWHKLRYDPILRFLIVSLSF
YGMSTFEGPMMSIKTVNALSHYTDWTIGHVHSGALGWVAMVSIGSVYHLIPRLFGQERMYSVSLINAHFWLATIGTVLYI
VAMWISGVMQGLMWRAVNSDGTLTYSFVESVQASYPFYTVRFIGGFIFLSGMFLMAYNAYKTISAPKNSLKAIVQPA

Sequences:

>Translated_477_residues
MQMSQEKQLEQNYNYTVVRQFTLVTILWGIVGMAVGVLIAAQLVWPQLNFDTPWLTYSRLRPLHTNAVIFAFGTSALFAT
SYYVVQRTCQTRLFGGPLVPFTFWGWQAIIVSAAITLPLGYTSGKEYAELEWPIDIAIAAVWVAYAVVFFGTLVKRKTSH
IYVANWFFGAFIITVAVLHIVNSMALPVSMGKSYSIYAGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYS
YRLSIVHFWALISLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAWHKLRYDPILRFLIVSLSF
YGMSTFEGPMMSIKTVNALSHYTDWTIGHVHSGALGWVAMVSIGSVYHLIPRLFGQERMYSVSLINAHFWLATIGTVLYI
VAMWISGVMQGLMWRAVNSDGTLTYSFVESVQASYPFYTVRFIGGFIFLSGMFLMAYNAYKTISAPKNSLKAIVQPA
>Mature_477_residues
MQMSQEKQLEQNYNYTVVRQFTLVTILWGIVGMAVGVLIAAQLVWPQLNFDTPWLTYSRLRPLHTNAVIFAFGTSALFAT
SYYVVQRTCQTRLFGGPLVPFTFWGWQAIIVSAAITLPLGYTSGKEYAELEWPIDIAIAAVWVAYAVVFFGTLVKRKTSH
IYVANWFFGAFIITVAVLHIVNSMALPVSMGKSYSIYAGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYS
YRLSIVHFWALISLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSGAWHKLRYDPILRFLIVSLSF
YGMSTFEGPMMSIKTVNALSHYTDWTIGHVHSGALGWVAMVSIGSVYHLIPRLFGQERMYSVSLINAHFWLATIGTVLYI
VAMWISGVMQGLMWRAVNSDGTLTYSFVESVQASYPFYTVRFIGGFIFLSGMFLMAYNAYKTISAPKNSLKAIVQPA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG3278

COG function: function code O; Cbb3-type cytochrome oxidase, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004677
- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 53644; Mature: 53644

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMSQEKQLEQNYNYTVVRQFTLVTILWGIVGMAVGVLIAAQLVWPQLNFDTPWLTYSRL
CCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHC
RPLHTNAVIFAFGTSALFATSYYVVQRTCQTRLFGGPLVPFTFWGWQAIIVSAAITLPLG
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECC
YTSGKEYAELEWPIDIAIAAVWVAYAVVFFGTLVKRKTSHIYVANWFFGAFIITVAVLHI
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHH
VNSMALPVSMGKSYSIYAGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYS
HHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHH
YRLSIVHFWALISLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSG
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
AWHKLRYDPILRFLIVSLSFYGMSTFEGPMMSIKTVNALSHYTDWTIGHVHSGALGWVAM
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHH
VSIGSVYHLIPRLFGQERMYSVSLINAHFWLATIGTVLYIVAMWISGVMQGLMWRAVNSD
HHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
GTLTYSFVESVQASYPFYTVRFIGGFIFLSGMFLMAYNAYKTISAPKNSLKAIVQPA
CCEEHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
>Mature Secondary Structure
MQMSQEKQLEQNYNYTVVRQFTLVTILWGIVGMAVGVLIAAQLVWPQLNFDTPWLTYSRL
CCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHC
RPLHTNAVIFAFGTSALFATSYYVVQRTCQTRLFGGPLVPFTFWGWQAIIVSAAITLPLG
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECC
YTSGKEYAELEWPIDIAIAAVWVAYAVVFFGTLVKRKTSHIYVANWFFGAFIITVAVLHI
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHH
VNSMALPVSMGKSYSIYAGAVDAMVQWWYGHNAVGFLLTAGFLGMMYYFVPKQAERPVYS
HHHHCCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHH
YRLSIVHFWALISLYIWAGPHHLHYTALPDWTQSLGMVMSLVLFAPSWGGMINGIMTLSG
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
AWHKLRYDPILRFLIVSLSFYGMSTFEGPMMSIKTVNALSHYTDWTIGHVHSGALGWVAM
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCCCHHHHHHH
VSIGSVYHLIPRLFGQERMYSVSLINAHFWLATIGTVLYIVAMWISGVMQGLMWRAVNSD
HHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
GTLTYSFVESVQASYPFYTVRFIGGFIFLSGMFLMAYNAYKTISAPKNSLKAIVQPA
CCEEHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7891558 [H]