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The map label for this gene is fnr

Identifier: 227081606

GI number: 227081606

Start: 1489159

End: 1489911

Strand: Reverse

Name: fnr

Synonym: VCM66_1390

Alternate gene names: 227081606

Gene position: 1489911-1489159 (Counterclockwise)

Preceding gene: 227081607

Following gene: 227081605

Centisome position: 51.51

GC content: 43.29

Gene sequence:

>753_bases
ATGATTTCTGAAAAGCCTGCTGCGAAGCGCATTCAATCGGGTGGTTGTGCTATTCACTGTCAAGATTGCAGTATTAGCCA
ACTCTGTATCCCTTTTACCTTGAATGAGTCTGAGCTTGATCAGCTTGACCAGATCATTGAGCGTAAAAAACCGATCCAGA
AAGGTCAGGAGCTGTTTAAAGCGGGTGACGAACTGAGATCTTTATACGCAATTCGTTCTGGTACGATTAAAAGCTACACC
ATCACTGAGCAAGGTGATGAGCAGATCACAGCCTTTCATCTGGCTGGTGATTTAGTTGGTTTTGATGCAATTACTGGAGA
TCAGCACCCAAGCTTTGCTCAAGCGCTTGAGACCTCCATGGTTTGTGAAATCCCGTATGAAATCTTGGATGACCTGTCTG
GCAAAATGCCGAAACTGCGTCAACAAATCATGCGTTTAATGAGTAACGAAATTAAAGGCGATCAGGAGATGATCCTGCTG
CTTTCAAAGAAGAACGCTGAAGAACGTTTAGCGGCCTTCTTGTACAACCTTTCTACTCGTTTCTCTCAACGCGGTTTTAG
CCCAAGAGAGTTTCGTCTTACCATGACACGTGGTGATATTGGTAACTACCTTGGTCTTACTGTTGAAACCATCAGCCGCT
TGCTCGGTCGTTTCCAAAAATCAGAAATCCTAAGTGTTAAAGGCAAATACATCACTATTCTCAACCATGCAGAATTGATG
GAATTGGCTGGCGTATCTAAAGAATCTAAATAA

Upstream 100 bases:

>100_bases
ATCTGGGTTAATGGTTTAGAGGTCGCTGATGTATTTTAACTACCCTTTAGGGTTAAGCGATGCTAAAATATTGACGTACA
TCAATTAGTGAAAGGTTGTT

Downstream 100 bases:

>100_bases
CTTCAATGATGTAGCTCTTAATGAGCTACATCATATTTCTTCCAAATACCTCTTCTTTTTACTAAAACTCTGCTCATAAC
TAAGCTAAAGTGAAGCTAAC

Product: fumarate/nitrate reduction transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MISEKPAAKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDQIIERKKPIQKGQELFKAGDELRSLYAIRSGTIKSYT
ITEQGDEQITAFHLAGDLVGFDAITGDQHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILL
LSKKNAEERLAAFLYNLSTRFSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILNHAELM
ELAGVSKESK

Sequences:

>Translated_250_residues
MISEKPAAKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDQIIERKKPIQKGQELFKAGDELRSLYAIRSGTIKSYT
ITEQGDEQITAFHLAGDLVGFDAITGDQHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILL
LSKKNAEERLAAFLYNLSTRFSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILNHAELM
ELAGVSKESK
>Mature_250_residues
MISEKPAAKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDQIIERKKPIQKGQELFKAGDELRSLYAIRSGTIKSYT
ITEQGDEQITAFHLAGDLVGFDAITGDQHPSFAQALETSMVCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILL
LSKKNAEERLAAFLYNLSTRFSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILNHAELM
ELAGVSKESK

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1787595, Length=247, Percent_Identity=85.82995951417, Blast_Score=436, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FNR_VIBC3 (A5F890)

Other databases:

- EMBL:   AF244992
- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F890
- SMR:   A5F890
- STRING:   A5F890
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1045
- eggNOG:   COG0664
- HOGENOM:   HBG753167
- OMA:   FSANQFR
- ProtClustDB:   PRK11161
- BioCyc:   VCHO345073:VC0395_A1045-MONOMER
- GO:   GO:0005737
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991
- Gene3D:   G3DSA:2.60.120.10
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00034
- SMART:   SM00100
- SMART:   SM00419

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp; SSF51206 cNMP_binding

EC number: NA

Molecular weight: Translated: 28072; Mature: 28072

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50042 CNMP_BINDING_3; PS00042 HTH_CRP_1; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISEKPAAKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDQIIERKKPIQKGQELFK
CCCCCCHHHHHHCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHH
AGDELRSLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAITGDQHPSFAQALETSM
HHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHH
VCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILLLSKKNAEERLAAFLYNLSTR
HHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
FSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILNHAELM
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECHHHHH
ELAGVSKESK
HHHCCCCCCC
>Mature Secondary Structure
MISEKPAAKRIQSGGCAIHCQDCSISQLCIPFTLNESELDQLDQIIERKKPIQKGQELFK
CCCCCCHHHHHHCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHH
AGDELRSLYAIRSGTIKSYTITEQGDEQITAFHLAGDLVGFDAITGDQHPSFAQALETSM
HHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHH
VCEIPYEILDDLSGKMPKLRQQIMRLMSNEIKGDQEMILLLSKKNAEERLAAFLYNLSTR
HHCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
FSQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSEILSVKGKYITILNHAELM
HHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEECHHHHH
ELAGVSKESK
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA