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The map label for this gene is potC [H]

Identifier: 227081598

GI number: 227081598

Start: 1481617

End: 1482387

Strand: Reverse

Name: potC [H]

Synonym: VCM66_1382

Alternate gene names: 227081598

Gene position: 1482387-1481617 (Counterclockwise)

Preceding gene: 227081599

Following gene: 227081597

Centisome position: 51.25

GC content: 44.62

Gene sequence:

>771_bases
ATGGGACGTTCAATTAGATTTAGCTTTATGAGTTTGGTGTACTTATTTTTGTACTTACCAATCATCGTTCTGATTGCAAA
CTCATTTAACGAAAACAAGTTTGGTATCAAATGGGGCGGTTTTACCACCAAGTGGTACCACGCTTTGATGAATAACGACA
GCTTAATGCAAGCCGCTTGGCACTCCATCAACGTAGCGGTGTTTTCTGCTACTGCAGCAACCTTGATCGGTAGTTTGACG
GCGGTTGCCCTCTTCCGTTACCAATTTAAAGGTAAGAAAGTGGTGAGTGGCATGCTGTTTGTCGTGATGATGTCACCCGA
TATCGTGATGGCTATTTCGCTGCTTGCTTTGTTCTTAGTGATGGGAGCGAAACTGGGCTTCTTCACTCTGTTGATTGCGC
ACATCACTTTCTGTCTGCCTTTCGTTGTGGTGACGGTTTACACTCGACTCAACGGCTTTGACGTTAAGATGCTTGAAGCA
GCAAAAGATCTCGGCGCTGGCGAATGGGTGATTTTAAAGAAAATTATCCTACCACTGGCGAAACCTGCGGTTGCCGCAGG
TTGGTTACTGAGCTTTACCCTATCTCTGGATGATGTGATCATCAGTTCATTTGTGACAGGGCCAACCTACGAAATTCTGC
CATTGAAGATATACTCAATGGTGAAAGTGGGTATTTCACCTGAAGTAAACGCACTGGCGACCGTCATGCTTGTGGTTTCT
TTGGTACTTGTTGTCGCTTCACAGTTGTTAGCAAGAGAAAAAGTGAAGTAA

Upstream 100 bases:

>100_bases
GTGCCGCAACCAGTATTGCACTGACTCTGGCCATGGCGATCATGCTGTACGCCTACTATCGTGCAGGTAAACTTTTGAAT
AAGAAGGTGGAGCTAGACTA

Downstream 100 bases:

>100_bases
AATCCACGTCCGTTTGGAAACACGCGAAACAGAATGACGGAAGTCATTCTGTTTTTCTTTGCAACGCCCAAAAGGGCAAC
GTTTAGTTTGGAGCTAACGT

Product: spermidine/putrescine ABC transporter membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MGRSIRFSFMSLVYLFLYLPIIVLIANSFNENKFGIKWGGFTTKWYHALMNNDSLMQAAWHSINVAVFSATAATLIGSLT
AVALFRYQFKGKKVVSGMLFVVMMSPDIVMAISLLALFLVMGAKLGFFTLLIAHITFCLPFVVVTVYTRLNGFDVKMLEA
AKDLGAGEWVILKKIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLVVS
LVLVVASQLLAREKVK

Sequences:

>Translated_256_residues
MGRSIRFSFMSLVYLFLYLPIIVLIANSFNENKFGIKWGGFTTKWYHALMNNDSLMQAAWHSINVAVFSATAATLIGSLT
AVALFRYQFKGKKVVSGMLFVVMMSPDIVMAISLLALFLVMGAKLGFFTLLIAHITFCLPFVVVTVYTRLNGFDVKMLEA
AKDLGAGEWVILKKIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLVVS
LVLVVASQLLAREKVK
>Mature_255_residues
GRSIRFSFMSLVYLFLYLPIIVLIANSFNENKFGIKWGGFTTKWYHALMNNDSLMQAAWHSINVAVFSATAATLIGSLTA
VALFRYQFKGKKVVSGMLFVVMMSPDIVMAISLLALFLVMGAKLGFFTLLIAHITFCLPFVVVTVYTRLNGFDVKMLEAA
KDLGAGEWVILKKIILPLAKPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLVVSL
VLVVASQLLAREKVK

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=256, Percent_Identity=75.390625, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1787081, Length=260, Percent_Identity=40, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1787714, Length=242, Percent_Identity=30.5785123966942, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788764, Length=175, Percent_Identity=30.8571428571429, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28113; Mature: 27982

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GRSIRFSFMSLVYLFLYLPIIVLIANSFNENKFGIKWGGFTTKWYHALMNNDSLMQAAW
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHCCCHHHHHHH
HSINVAVFSATAATLIGSLTAVALFRYQFKGKKVVSGMLFVVMMSPDIVMAISLLALFLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
MGAKLGFFTLLIAHITFCLPFVVVTVYTRLNGFDVKMLEAAKDLGAGEWVILKKIILPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHC
KPAVAAGWLLSFTLSLDDVIISSFVTGPTYEILPLKIYSMVKVGISPEVNALATVMLVVS
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LVLVVASQLLAREKVK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]