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The map label for this gene is yusP [H]

Identifier: 227081562

GI number: 227081562

Start: 1439042

End: 1440448

Strand: Direct

Name: yusP [H]

Synonym: VCM66_1346

Alternate gene names: 227081562

Gene position: 1439042-1440448 (Clockwise)

Preceding gene: 227081560

Following gene: 227081563

Centisome position: 49.75

GC content: 52.45

Gene sequence:

>1407_bases
ATGCATTTTGATCCTATTCCCGCTGCCGATGCCCCTCATCCGCGAATTATTTTTGCTAGCGTTGCGCTAGTGATTGCCCT
TGGTTCACTAGAAAAAAGCATAGTGACCACACCGCTGGCCTTGATTGGGCAAGATCTCTCGGCGGGAACCGCCTTAACTT
GGGTGATCACCGCCTACTTACTCGCCGCCACAGCCGTATTGCCTGTGTATGGCAAATTGAGCGATCTGTTTGGGCGTGTA
CGCATGCTCAATATCAGCATCGGTATTTTTATTGTTGGCTCAGCGATGTGTACCTTTGCCGTTGACTTACCAACCCTGAT
TGGGGCGCGAGTGGTGCAGGGAATTGGCGGCGGTGGTTTGATTGCTTTGGCGTTCACCGTGATTGCTGATTCCATTCCGG
CGCGTGAAGTCGGCAAATACCAAGGCTATATTTCGGCGGTGTATGCGGTTTCCAGTGTCGCTGGCCCCTTGCTTGGCGGC
TATTTTGCCGATCACCTCAGTTGGCGCTGGGTGTTTGGCATTAATTTACCGCTGGGAATGGTGGCTCTGTATATGGTCAA
CCGCCATCTCAGACACCTTAACCAAAAACGTCACAGTCGATTTGACTGGCTGGGCGCTGGGCTTTTAATGCTCACCACAA
CTTTGCTGCTGCTTCAGCTTTCCTCACACTCCTTTTTGCCTGCGGGGTGGGGAGCTTTTGCTCTGTTACTCTGCTTGGTG
CTGTTAATCCTTGTGGAAAGACAGGTGAGTGACCCGATTTTGCCTGCGCGTTTGGCACGCTTACCCAGTTACCTGACCGC
GATTGGTCTAATCATGGCCTCACAAATGTTGATGTTCGCGCTTTTGGTTTATATGCCGCTGCAATTGCAGTGGCAGAAAG
GCTTTTCACCGTCGCAAAGTGGCACCGTGATGGTGATTTTCATGTTCAGTATCACCACCGGAGCTTATCTTGGTGGCAAA
TGGGTGGCTCGCTCAGGGCGATATAAAGCGCTGGTGGTGAGCGGTTTTCTGCTTGCTGCCGTCGCCATCTGGCAGATTCA
CTACGATTTGTGGGTTCATCTCTCGCTAGGTATTGGCGGCCTTGGGCTTGGTTTCACTCTGCCTTCTCTTAATGTGGTGG
TACAGAGTGTGTTGCCTGCCCGTGATAGGGGTATTGGCATGTCACTGTTTAACTTTGGTCGTGAGCTTGGCGGCGCACTC
GGGGTGGCGTTCTGTTCTGCGCTGTTTTATCTGCGTGTGCCGCAAAGTGTCACGGTAAGTGAGCATGGCAGCCAAGCCTC
ATCAGTAACGCCTGATGTGCTCGCCCAAGGTTTTAGTTTGGTGTACATCGGCATGAGTGCGTTGGCGGTTGTGGCGATGA
TACTGACCGCTTGGCGTTTACGTAAAGATGCGCTGAAAGGGCACTAG

Upstream 100 bases:

>100_bases
ATTTCGCGTCCCATTCTATCCTATTTTCGGATGGCTGTGATTTGGTTATCTTGTGCCACAGCAAATCCATTCCCTTTGAC
TTTATCTTGAAAGAGAGCTC

Downstream 100 bases:

>100_bases
CCTCTCTCTGTGTTCAATAGAAAATAAGGTGATAAATAGAAAACTCGGTAATAGGCAGAAAGTGAGGTAATAGAAAGAGA
AGCGATAGATAGAACACGGG

Product: putative multidrug transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MHFDPIPAADAPHPRIIFASVALVIALGSLEKSIVTTPLALIGQDLSAGTALTWVITAYLLAATAVLPVYGKLSDLFGRV
RMLNISIGIFIVGSAMCTFAVDLPTLIGARVVQGIGGGGLIALAFTVIADSIPAREVGKYQGYISAVYAVSSVAGPLLGG
YFADHLSWRWVFGINLPLGMVALYMVNRHLRHLNQKRHSRFDWLGAGLLMLTTTLLLLQLSSHSFLPAGWGAFALLLCLV
LLILVERQVSDPILPARLARLPSYLTAIGLIMASQMLMFALLVYMPLQLQWQKGFSPSQSGTVMVIFMFSITTGAYLGGK
WVARSGRYKALVVSGFLLAAVAIWQIHYDLWVHLSLGIGGLGLGFTLPSLNVVVQSVLPARDRGIGMSLFNFGRELGGAL
GVAFCSALFYLRVPQSVTVSEHGSQASSVTPDVLAQGFSLVYIGMSALAVVAMILTAWRLRKDALKGH

Sequences:

>Translated_468_residues
MHFDPIPAADAPHPRIIFASVALVIALGSLEKSIVTTPLALIGQDLSAGTALTWVITAYLLAATAVLPVYGKLSDLFGRV
RMLNISIGIFIVGSAMCTFAVDLPTLIGARVVQGIGGGGLIALAFTVIADSIPAREVGKYQGYISAVYAVSSVAGPLLGG
YFADHLSWRWVFGINLPLGMVALYMVNRHLRHLNQKRHSRFDWLGAGLLMLTTTLLLLQLSSHSFLPAGWGAFALLLCLV
LLILVERQVSDPILPARLARLPSYLTAIGLIMASQMLMFALLVYMPLQLQWQKGFSPSQSGTVMVIFMFSITTGAYLGGK
WVARSGRYKALVVSGFLLAAVAIWQIHYDLWVHLSLGIGGLGLGFTLPSLNVVVQSVLPARDRGIGMSLFNFGRELGGAL
GVAFCSALFYLRVPQSVTVSEHGSQASSVTPDVLAQGFSLVYIGMSALAVVAMILTAWRLRKDALKGH
>Mature_468_residues
MHFDPIPAADAPHPRIIFASVALVIALGSLEKSIVTTPLALIGQDLSAGTALTWVITAYLLAATAVLPVYGKLSDLFGRV
RMLNISIGIFIVGSAMCTFAVDLPTLIGARVVQGIGGGGLIALAFTVIADSIPAREVGKYQGYISAVYAVSSVAGPLLGG
YFADHLSWRWVFGINLPLGMVALYMVNRHLRHLNQKRHSRFDWLGAGLLMLTTTLLLLQLSSHSFLPAGWGAFALLLCLV
LLILVERQVSDPILPARLARLPSYLTAIGLIMASQMLMFALLVYMPLQLQWQKGFSPSQSGTVMVIFMFSITTGAYLGGK
WVARSGRYKALVVSGFLLAAVAIWQIHYDLWVHLSLGIGGLGLGFTLPSLNVVVQSVLPARDRGIGMSLFNFGRELGGAL
GVAFCSALFYLRVPQSVTVSEHGSQASSVTPDVLAQGFSLVYIGMSALAVVAMILTAWRLRKDALKGH

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=402, Percent_Identity=29.3532338308458, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1790195, Length=407, Percent_Identity=25.7985257985258, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1789042, Length=424, Percent_Identity=25.2358490566038, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788710, Length=404, Percent_Identity=26.7326732673267, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788392, Length=422, Percent_Identity=25.8293838862559, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323735, Length=313, Percent_Identity=30.6709265175719, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6325455, Length=150, Percent_Identity=34.6666666666667, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6322958, Length=167, Percent_Identity=32.3353293413174, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321663, Length=149, Percent_Identity=30.8724832214765, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319770, Length=381, Percent_Identity=26.509186351706, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319783, Length=80, Percent_Identity=40, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50136; Mature: 50136

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFDPIPAADAPHPRIIFASVALVIALGSLEKSIVTTPLALIGQDLSAGTALTWVITAYL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHH
LAATAVLPVYGKLSDLFGRVRMLNISIGIFIVGSAMCTFAVDLPTLIGARVVQGIGGGGL
HHHHHHHHHHHHHHHHHHHEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IALAFTVIADSIPAREVGKYQGYISAVYAVSSVAGPLLGGYFADHLSWRWVFGINLPLGM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHH
VALYMVNRHLRHLNQKRHSRFDWLGAGLLMLTTTLLLLQLSSHSFLPAGWGAFALLLCLV
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LLILVERQVSDPILPARLARLPSYLTAIGLIMASQMLMFALLVYMPLQLQWQKGFSPSQS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
GTVMVIFMFSITTGAYLGGKWVARSGRYKALVVSGFLLAAVAIWQIHYDLWVHLSLGIGG
CCEEEEEEEHHHCCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
LGLGFTLPSLNVVVQSVLPARDRGIGMSLFNFGRELGGALGVAFCSALFYLRVPQSVTVS
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EHGSQASSVTPDVLAQGFSLVYIGMSALAVVAMILTAWRLRKDALKGH
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHFDPIPAADAPHPRIIFASVALVIALGSLEKSIVTTPLALIGQDLSAGTALTWVITAYL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHH
LAATAVLPVYGKLSDLFGRVRMLNISIGIFIVGSAMCTFAVDLPTLIGARVVQGIGGGGL
HHHHHHHHHHHHHHHHHHHEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
IALAFTVIADSIPAREVGKYQGYISAVYAVSSVAGPLLGGYFADHLSWRWVFGINLPLGM
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHH
VALYMVNRHLRHLNQKRHSRFDWLGAGLLMLTTTLLLLQLSSHSFLPAGWGAFALLLCLV
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LLILVERQVSDPILPARLARLPSYLTAIGLIMASQMLMFALLVYMPLQLQWQKGFSPSQS
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
GTVMVIFMFSITTGAYLGGKWVARSGRYKALVVSGFLLAAVAIWQIHYDLWVHLSLGIGG
CCEEEEEEEHHHCCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
LGLGFTLPSLNVVVQSVLPARDRGIGMSLFNFGRELGGALGVAFCSALFYLRVPQSVTVS
CCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EHGSQASSVTPDVLAQGFSLVYIGMSALAVVAMILTAWRLRKDALKGH
CCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]