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The map label for this gene is aspC [H]

Identifier: 227081464

GI number: 227081464

Start: 1328973

End: 1330214

Strand: Reverse

Name: aspC [H]

Synonym: VCM66_1248

Alternate gene names: 227081464

Gene position: 1330214-1328973 (Counterclockwise)

Preceding gene: 227081465

Following gene: 227081462

Centisome position: 45.99

GC content: 48.23

Gene sequence:

>1242_bases
TTGATGAGTTCAATCATCCCTTCCCACCCTAACTTGACATGGATGTGCTTTATGTTCGAAAAAGTCGTTGCCGCTCCCGC
TGACCCTATCCTAGGTTTAACTGAAGAGTTCAAAAAAGACCCTCGTACCGACAAAATTAACCTCGGTGTAGGTATTTATA
AGAATGAAGCAGGTGAAACCCCGGTTCTCGCTACTGTAAAGAAAGCAGAAGCCGCACTGCTTGAGTCAGAGAAAACCAAA
TCTTATCTCACGATCGAAGGGACAGCTGAGTACGGTTTAGCAGTACAAAAACTGCTGTTCGGCGCGAATTCGGACATAGT
GACACAAAAACTGGCAAAAACAGCGCAAGCCCCTGGTGGCACTGGTGCGCTGCGTGTGGCGGGTGAATTTATTAAGCGTC
AACTGGGCGATGTGAAAGTCTGGATCAGTAACCCAACTTGGGCTAACCATCACGGTGTGTTCAATGCCGCTGGCTTGGAA
ACTACGCAATACGCTTATTATGATGCCAAAGCCAAAGACAAAGATTTTGCCGCTATGCTGGCAGATTTAGAGCAGGCAGA
GAAAGGCGATGTGGTTTTACTGCATGGCTGCTGCCACAATCCAACGGGTATTGACCCAACAGAGCAAGAGTGGGAAGTAC
TGGCGAAATTGGTGGCTGACAAAGGCTTACTGCCTCTGTTTGACTTTGCTTACCAAGGCTTTGCTTCAGGTGTGGAAGAA
GACGCGGCTGGCCTACGTATTTTTGCGAAATACAACTCTGAGATTCTGGTTGCCAGCTCTTTCTCAAAGAACTTTGGCTT
GTACAACGAACGTGTCGGTGCCTTCACGCTGGTTGCACCTTCAACAACCGTTGCAGAAACGGCGTTCTCACAAGTTAAAG
CGATTATCCGCTCTATCTACTCAAACCCACCAGCTCACGGTGCTGCCGTTGTCACTTATATTCTGAACAACCCAGAATTA
CGCGCAGAATGGGAAGCCGAAGTCGCGGAAATGCGTGAACGTATTCAAGAGATGCGCGTACTTTTCGTTAACACATTGAA
AGAAGTGGGTGTAGACGCTGACTTTAGCTTTATCGAGCGTCAAAACGGCATGTTCTCTTTCTCTGGCCTAAGCAAAGAGC
AAGTTGCACGCCTCAAATCAGAGTTGGGTATCTATATCGTCGGCTCTGGCCGCATCAGCGTAGCGGGGATGACCAAATCA
AACATGCTACCCTTGTGCCAAGGCATTGCTGCGGTGATGTAA

Upstream 100 bases:

>100_bases
CCAACTATTCCCAGTTTTTCAGCCAAGTAAAAATTTTTCGATATTTTCTTTCAGGTGCTGTTGTCACCTGAATACGAGGG
AGGTATAAATACGGTAAATT

Downstream 100 bases:

>100_bases
TCGCATCGTCAATGACTCTCTTAAACCGGCTGGAATATGGCCGGTTTTTGTTTTTTTACTGTTCATATACCCAAACTACT
TGGAGTTGCAGGTAGGCGGC

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGETPVLATVKKAEAALLESEKTK
SYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGGTGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLE
TTQYAYYDAKAKDKDFAAMLADLEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEE
DAAGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIYSNPPAHGAAVVTYILNNPEL
RAEWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIERQNGMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKS
NMLPLCQGIAAVM

Sequences:

>Translated_413_residues
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGETPVLATVKKAEAALLESEKTK
SYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGGTGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLE
TTQYAYYDAKAKDKDFAAMLADLEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEE
DAAGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIYSNPPAHGAAVVTYILNNPEL
RAEWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIERQNGMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKS
NMLPLCQGIAAVM
>Mature_413_residues
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGETPVLATVKKAEAALLESEKTK
SYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGGTGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLE
TTQYAYYDAKAKDKDFAAMLADLEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEE
DAAGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIYSNPPAHGAAVVTYILNNPEL
RAEWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIERQNGMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKS
NMLPLCQGIAAVM

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=393, Percent_Identity=43.2569974554707, Blast_Score=326, Evalue=2e-89,
Organism=Homo sapiens, GI4504067, Length=393, Percent_Identity=41.2213740458015, Blast_Score=301, Evalue=5e-82,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=27.6762402088773, Blast_Score=152, Evalue=5e-37,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=62.3737373737374, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=43.8287153652393, Blast_Score=345, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI71981858, Length=413, Percent_Identity=41.6464891041162, Blast_Score=347, Evalue=6e-96,
Organism=Caenorhabditis elegans, GI25147133, Length=395, Percent_Identity=40.5063291139241, Blast_Score=317, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI17569539, Length=398, Percent_Identity=36.1809045226131, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17569537, Length=380, Percent_Identity=31.0526315789474, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI25147136, Length=218, Percent_Identity=38.0733944954128, Blast_Score=170, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=32.6996197718631, Blast_Score=160, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=36.2962962962963, Blast_Score=284, Evalue=2e-77,
Organism=Saccharomyces cerevisiae, GI6322743, Length=428, Percent_Identity=33.411214953271, Blast_Score=248, Evalue=2e-66,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=41.8546365914787, Blast_Score=324, Evalue=5e-89,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=41.8546365914787, Blast_Score=324, Evalue=7e-89,
Organism=Drosophila melanogaster, GI24580972, Length=402, Percent_Identity=40.547263681592, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI24580970, Length=402, Percent_Identity=40.547263681592, Blast_Score=316, Evalue=2e-86,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=40.8740359897172, Blast_Score=312, Evalue=3e-85,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44926; Mature: 44926

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGET
CCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCCCC
PVLATVKKAEAALLESEKTKSYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGG
CCEEHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
TGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLETTQYAYYDAKAKDKDFAAML
CCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEECCCCCCCEEEEEECCCCCHHHHHHH
ADLEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEE
HHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
DAAGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIY
CCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
SNPPAHGAAVVTYILNNPELRAEWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIER
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QNGMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKSNMLPLCQGIAAVM
CCCEEEECCCCHHHHHHHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MMSSIIPSHPNLTWMCFMFEKVVAAPADPILGLTEEFKKDPRTDKINLGVGIYKNEAGET
CCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEEEEEEEEECCCCCC
PVLATVKKAEAALLESEKTKSYLTIEGTAEYGLAVQKLLFGANSDIVTQKLAKTAQAPGG
CCEEHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCC
TGALRVAGEFIKRQLGDVKVWISNPTWANHHGVFNAAGLETTQYAYYDAKAKDKDFAAML
CCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEECCCCCCCEEEEEECCCCCHHHHHHH
ADLEQAEKGDVVLLHGCCHNPTGIDPTEQEWEVLAKLVADKGLLPLFDFAYQGFASGVEE
HHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
DAAGLRIFAKYNSEILVASSFSKNFGLYNERVGAFTLVAPSTTVAETAFSQVKAIIRSIY
CCCCEEEEEECCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHH
SNPPAHGAAVVTYILNNPELRAEWEAEVAEMRERIQEMRVLFVNTLKEVGVDADFSFIER
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QNGMFSFSGLSKEQVARLKSELGIYIVGSGRISVAGMTKSNMLPLCQGIAAVM
CCCEEEECCCCHHHHHHHHHHCCEEEEECCEEEEEECCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]