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The map label for this gene is cobC [C]

Identifier: 227081412

GI number: 227081412

Start: 1271339

End: 1271941

Strand: Direct

Name: cobC [C]

Synonym: VCM66_1195

Alternate gene names: 227081412

Gene position: 1271339-1271941 (Clockwise)

Preceding gene: 227081411

Following gene: 227081413

Centisome position: 43.95

GC content: 52.07

Gene sequence:

>603_bases
ATGATCCGAATTTGGTTACTGCGTCACGGCAAAACACAAGGCCCTGCAGCCCTGAATGGTATAACGGATGTCGCGGTGAA
GCCGAGCGTGCAGCAAGCGATAGCCAGCCAATTGAGCACTTTGCCGTTTACTCGTGTGATAAGCTCCCCCTTACGTCGCT
GCGCCGATCTGGCGCGATTGCTCCAATCAGCTCGTCCGCACGTTATGCTCGATTTCGACCCGCAGCTCCAAGAGCTTAAC
TTTGGTGAGTTGGATGGACAAAGTTTTGCCGACTTGGAGACTCAATGGCCAATATTGGATGCCTTTTGGCAAGACCCCGC
AAAGAACACACTGCCACAAGCTGAACCTCTCGCTATGGCCTATCAAAGAGTGAGTCAAGCTTGGCAACAATGGTTACCTA
AGCTTGAGAGCGATACGCTTATCCTCTGCCATGCAGGAACCATACGTTTGATTTTGGCACACGTATTGGGTGTCGATTGG
CGCAACCCACACTGGCATACTCGGTTAACCATTCCTCATCAATCGGTGACAGAGCTTGTCCTTTATCCCGGTGAGCCACC
GATAGTGAGCGTGACCAGCATCGGAAATGCGCTTTGCCGTTAG

Upstream 100 bases:

>100_bases
CCACGCGGGATGGATGAACCAGAAAATCGCGGCATTGGCCGATTCGGTAACGTTTGTCGTGGCGGGTCTGCCACAGCGTT
TAAAAGGCGAGTAGCAAGGC

Downstream 100 bases:

>100_bases
CCCATAAAGCGAATTGAATATGGAGCATCTCATTGAATTAGTGGTAGAATCCGCGCCTATATCGTCGTCTGGCTGGGAAT
AAAAAGATCTATTCCTTGAT

Product: putative alpha-ribazole-5`-phosphate phosphatase CobC

Products: alpha-ribazole; phosphate

Alternate protein names: Alpha-Ribazole Phosphatase; Alpha-Ribazole-5-Phosphate Phosphatase; Alpha-Ribazole-5`-Phosphate Phosphatase CobC; Fructose-2 6-Bisphosphatase; Phosphoglycerate/Bisphosphoglycerate Mutase; Phosphoglycerate Mutase Family Protein; Phosphoglycerate Mutase Domain Protein; Enzymatic Protein; 7 Alpha-Ribazole-5-Phosphate Phosphatase; Alpha-Ribazole-5-Phosphate Phosphatase CobC; Fis Family Transcriptional Regulator; Phosphoglycerate Mutase Family; Phosphatase PhoE

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MIRIWLLRHGKTQGPAALNGITDVAVKPSVQQAIASQLSTLPFTRVISSPLRRCADLARLLQSARPHVMLDFDPQLQELN
FGELDGQSFADLETQWPILDAFWQDPAKNTLPQAEPLAMAYQRVSQAWQQWLPKLESDTLILCHAGTIRLILAHVLGVDW
RNPHWHTRLTIPHQSVTELVLYPGEPPIVSVTSIGNALCR

Sequences:

>Translated_200_residues
MIRIWLLRHGKTQGPAALNGITDVAVKPSVQQAIASQLSTLPFTRVISSPLRRCADLARLLQSARPHVMLDFDPQLQELN
FGELDGQSFADLETQWPILDAFWQDPAKNTLPQAEPLAMAYQRVSQAWQQWLPKLESDTLILCHAGTIRLILAHVLGVDW
RNPHWHTRLTIPHQSVTELVLYPGEPPIVSVTSIGNALCR
>Mature_200_residues
MIRIWLLRHGKTQGPAALNGITDVAVKPSVQQAIASQLSTLPFTRVISSPLRRCADLARLLQSARPHVMLDFDPQLQELN
FGELDGQSFADLETQWPILDAFWQDPAKNTLPQAEPLAMAYQRVSQAWQQWLPKLESDTLILCHAGTIRLILAHVLGVDW
RNPHWHTRLTIPHQSVTELVLYPGEPPIVSVTSIGNALCR

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.73

Molecular weight: Translated: 22430; Mature: 22430

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIWLLRHGKTQGPAALNGITDVAVKPSVQQAIASQLSTLPFTRVISSPLRRCADLARL
CEEEEEEECCCCCCCHHHCCCHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LQSARPHVMLDFDPQLQELNFGELDGQSFADLETQWPILDAFWQDPAKNTLPQAEPLAMA
HHHCCCCEEEECCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHH
YQRVSQAWQQWLPKLESDTLILCHAGTIRLILAHVLGVDWRNPHWHTRLTIPHQSVTELV
HHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEE
LYPGEPPIVSVTSIGNALCR
EECCCCCEEEHHHHHHHHCC
>Mature Secondary Structure
MIRIWLLRHGKTQGPAALNGITDVAVKPSVQQAIASQLSTLPFTRVISSPLRRCADLARL
CEEEEEEECCCCCCCHHHCCCHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
LQSARPHVMLDFDPQLQELNFGELDGQSFADLETQWPILDAFWQDPAKNTLPQAEPLAMA
HHHCCCCEEEECCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHH
YQRVSQAWQQWLPKLESDTLILCHAGTIRLILAHVLGVDWRNPHWHTRLTIPHQSVTELV
HHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCEEE
LYPGEPPIVSVTSIGNALCR
EECCCCCEEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alpha-ribazole 5'-phosphate; H2O

Specific reaction: alpha-ribazole 5'-phosphate + H2O = alpha-ribazole + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA