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The map label for this gene is cobU [H]

Identifier: 227081411

GI number: 227081411

Start: 1270793

End: 1271332

Strand: Direct

Name: cobU [H]

Synonym: VCM66_1194

Alternate gene names: 227081411

Gene position: 1270793-1271332 (Clockwise)

Preceding gene: 227081410

Following gene: 227081412

Centisome position: 43.93

GC content: 52.22

Gene sequence:

>540_bases
GTGACGGTTCATTTCGTTTTAGGTGGTGCCCGTAGTGGTAAATCGAGTTACGCAGAGTTACTCGCCAAACAAACTGCACA
AGCTTTGGGGGCGACCTTGCATTATGTGGCGACCGCCACGGCCTTAGATGATGAGATGCGCGAGCGGATTGCTCATCATC
AAGCCCGACGAACCGCAGAGTGGAATGAACATGAAGTGCCGCTGGCTTTGGCTGAGGCGTTAACTCGCTTTCAACGCCAA
GATTTGGTGTTAGTCGATTGCCTCACGTTATGGCTCAATAATCTGCTTTTTGAACACGAAGCCGCGCTCTGTGCAGCGCG
GATTGAGCAGCATGTCGATTCGCTGTTGGCGGCATTGGCTCAAACCCAAGCTCACATTATTTTGGTCAGCAATGAAGTGG
GTATGGGAGTCGTACCTATGGGCGAATTGACTCGCATGTTTGTTGACCACGCGGGATGGATGAACCAGAAAATCGCGGCA
TTGGCCGATTCGGTAACGTTTGTCGTGGCGGGTCTGCCACAGCGTTTAAAAGGCGAGTAG

Upstream 100 bases:

>100_bases
CTGGCGATTGCCTTGGCGCCGCACAGCAGTTGATGGAAATTCTGATCTATCTGATCTTGCTTGCTTTTTTACAGCATGAA
GTGATGATTTAGGGGGCAAA

Downstream 100 bases:

>100_bases
CAAGGCATGATCCGAATTTGGTTACTGCGTCACGGCAAAACACAAGGCCCTGCAGCCCTGAATGGTATAACGGATGTCGC
GGTGAAGCCGAGCGTGCAGC

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MTVHFVLGGARSGKSSYAELLAKQTAQALGATLHYVATATALDDEMRERIAHHQARRTAEWNEHEVPLALAEALTRFQRQ
DLVLVDCLTLWLNNLLFEHEAALCAARIEQHVDSLLAALAQTQAHIILVSNEVGMGVVPMGELTRMFVDHAGWMNQKIAA
LADSVTFVVAGLPQRLKGE

Sequences:

>Translated_179_residues
MTVHFVLGGARSGKSSYAELLAKQTAQALGATLHYVATATALDDEMRERIAHHQARRTAEWNEHEVPLALAEALTRFQRQ
DLVLVDCLTLWLNNLLFEHEAALCAARIEQHVDSLLAALAQTQAHIILVSNEVGMGVVPMGELTRMFVDHAGWMNQKIAA
LADSVTFVVAGLPQRLKGE
>Mature_178_residues
TVHFVLGGARSGKSSYAELLAKQTAQALGATLHYVATATALDDEMRERIAHHQARRTAEWNEHEVPLALAEALTRFQRQD
LVLVDCLTLWLNNLLFEHEAALCAARIEQHVDSLLAALAQTQAHIILVSNEVGMGVVPMGELTRMFVDHAGWMNQKIAAL
ADSVTFVVAGLPQRLKGE

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=183, Percent_Identity=38.7978142076503, Blast_Score=114, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19646; Mature: 19515

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHFVLGGARSGKSSYAELLAKQTAQALGATLHYVATATALDDEMRERIAHHQARRTAE
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WNEHEVPLALAEALTRFQRQDLVLVDCLTLWLNNLLFEHEAALCAARIEQHVDSLLAALA
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTQAHIILVSNEVGMGVVPMGELTRMFVDHAGWMNQKIAALADSVTFVVAGLPQRLKGE
HCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
TVHFVLGGARSGKSSYAELLAKQTAQALGATLHYVATATALDDEMRERIAHHQARRTAE
EEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
WNEHEVPLALAEALTRFQRQDLVLVDCLTLWLNNLLFEHEAALCAARIEQHVDSLLAALA
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTQAHIILVSNEVGMGVVPMGELTRMFVDHAGWMNQKIAALADSVTFVVAGLPQRLKGE
HCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1655696 [H]