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The map label for this gene is hutI

Identifier: 227081377

GI number: 227081377

Start: 1237993

End: 1239201

Strand: Reverse

Name: hutI

Synonym: VCM66_1160

Alternate gene names: 227081377

Gene position: 1239201-1237993 (Counterclockwise)

Preceding gene: 227081378

Following gene: 227081376

Centisome position: 42.84

GC content: 53.02

Gene sequence:

>1209_bases
ATGAATTGTGTGTTGACCGAAGCGCGTTTAGTAACCATGCAACCGGGCGTGCAAGGTTATCAGATAACCGAGCCGCAAAC
CCTCATCATTGAGCAGGGGCGCATTCAACACATTGGCCAACATATTGACCTTCCCAGCGATGCGCATCCTATCTCGTGTG
CCGGCAAATTAGTCACACCGGGATTGATTGATTGCCACACCCATTTGGTTTATGCCGGCAGCCGCGCCAACGAATTCGAG
CTGCGTTTACAAGGTGTGCCCTACCAAACCATCGCCGCTCAAGGTGGCGGCATTCTTTCTACCGTGAATGCCACTCGTAA
GGCCAGTGAAGAAGCGTTGATCGAACTCGCGCTACCGCGTTTGGATGGCCTGCTGCGTAGCGGTGTCACTTCCGTTGAAG
TGAAATCTGGCTACGGTTTAACGCTCAAGGATGAGCTGAAAATGCTGCGCGCCGCCAAAGCGCTTGAGCAGCATCGCCGC
GTCAAAATCACCACCACATTACTTGCCGCGCACGCACTACCTCCTGAATTTCAAGGCCGTAGTGATGACTATATCGCGCA
TATTTGCCAAGAGATCATTCCTCGGGTTGCCGAAGAGCAACTGGCCACCAGCGTAGATGTGTTTTGTGAGTCGATTGGCT
TTAGCGTGGCGCAAACTGAACGCGTGTTTCATGCTGCGCAAGCGCATGGCTTGCAAATCAAAGGTCATACCGAGCAGCTT
TCCAACTTAGGCGGCAGCGCACTCACCGCTCGCATGGGTGGGCTCTCCGTTGACCATATCGAATATCTTGATGAAGCGGG
CGTGAAAGCATTGGCGCAATCGAGCACGGTTGCCACCTTACTTCCCGGTGCATTCTACTTTTTGCGCGAAACCCAAAAGC
CGCCGATTGAATGGCTGCGCCAATATCGCGTACCCATGGCCATCTCTACCGATTTAAACCCCGGCACCTCACCATTTGCC
GATTTGTCCCTGATGATGAATATGGGCTGTACCTTGTTTGACCTAACGCCAGAAGAGACTCTACGCGCAGTGACATGCCA
TGCAGCGCAAGCCTTGGGTTACCCCGCAAACCGTGGACAAATCGCAGAAGGCTACGATGCTGATTTGGCGATTTGGAATA
TCGAACATCCTGCCGAGCTGAGCTATCAAGTCGGCGTTTCTCGCCTGCATGCTCGCATAGTTAATGGAGAGCTGAGCTAT
GAATCCTAA

Upstream 100 bases:

>100_bases
CACATGATCACATTTTCGCAACATTCAAGTTGCGAACTTTCACGCTTTCCACTATTTATTTGTATATACATTTGAAATAT
CGATATCTGGATGGAAAGCG

Downstream 100 bases:

>100_bases
TTTCACCACTGAGCACACTTGGCAAGGCCGCCATGATCCCGAAGATGGTCAAGCCGGGCGTCGTGTGCACCATATCGCTT
GTCCCATTCAAGTGGGCGAG

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MNCVLTEARLVTMQPGVQGYQITEPQTLIIEQGRIQHIGQHIDLPSDAHPISCAGKLVTPGLIDCHTHLVYAGSRANEFE
LRLQGVPYQTIAAQGGGILSTVNATRKASEEALIELALPRLDGLLRSGVTSVEVKSGYGLTLKDELKMLRAAKALEQHRR
VKITTTLLAAHALPPEFQGRSDDYIAHICQEIIPRVAEEQLATSVDVFCESIGFSVAQTERVFHAAQAHGLQIKGHTEQL
SNLGGSALTARMGGLSVDHIEYLDEAGVKALAQSSTVATLLPGAFYFLRETQKPPIEWLRQYRVPMAISTDLNPGTSPFA
DLSLMMNMGCTLFDLTPEETLRAVTCHAAQALGYPANRGQIAEGYDADLAIWNIEHPAELSYQVGVSRLHARIVNGELSY
ES

Sequences:

>Translated_402_residues
MNCVLTEARLVTMQPGVQGYQITEPQTLIIEQGRIQHIGQHIDLPSDAHPISCAGKLVTPGLIDCHTHLVYAGSRANEFE
LRLQGVPYQTIAAQGGGILSTVNATRKASEEALIELALPRLDGLLRSGVTSVEVKSGYGLTLKDELKMLRAAKALEQHRR
VKITTTLLAAHALPPEFQGRSDDYIAHICQEIIPRVAEEQLATSVDVFCESIGFSVAQTERVFHAAQAHGLQIKGHTEQL
SNLGGSALTARMGGLSVDHIEYLDEAGVKALAQSSTVATLLPGAFYFLRETQKPPIEWLRQYRVPMAISTDLNPGTSPFA
DLSLMMNMGCTLFDLTPEETLRAVTCHAAQALGYPANRGQIAEGYDADLAIWNIEHPAELSYQVGVSRLHARIVNGELSY
ES
>Mature_402_residues
MNCVLTEARLVTMQPGVQGYQITEPQTLIIEQGRIQHIGQHIDLPSDAHPISCAGKLVTPGLIDCHTHLVYAGSRANEFE
LRLQGVPYQTIAAQGGGILSTVNATRKASEEALIELALPRLDGLLRSGVTSVEVKSGYGLTLKDELKMLRAAKALEQHRR
VKITTTLLAAHALPPEFQGRSDDYIAHICQEIIPRVAEEQLATSVDVFCESIGFSVAQTERVFHAAQAHGLQIKGHTEQL
SNLGGSALTARMGGLSVDHIEYLDEAGVKALAQSSTVATLLPGAFYFLRETQKPPIEWLRQYRVPMAISTDLNPGTSPFA
DLSLMMNMGCTLFDLTPEETLRAVTCHAAQALGYPANRGQIAEGYDADLAIWNIEHPAELSYQVGVSRLHARIVNGELSY
ES

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=360, Percent_Identity=35, Blast_Score=187, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17555004, Length=365, Percent_Identity=31.2328767123288, Blast_Score=200, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_VIBC3 (A5F1X8)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F1X8
- SMR:   A5F1X8
- STRING:   A5F1X8
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0825
- eggNOG:   COG1228
- HOGENOM:   HBG686142
- OMA:   MNMACTL
- ProtClustDB:   PRK09356
- BioCyc:   VCHO345073:VC0395_A0825-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 43710; Mature: 43710

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: BINDING 75-75 BINDING 88-88 BINDING 138-138 BINDING 171-171 BINDING 239-239

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNCVLTEARLVTMQPGVQGYQITEPQTLIIEQGRIQHIGQHIDLPSDAHPISCAGKLVTP
CCCEEECCEEEEECCCCCCEEECCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCC
GLIDCHTHLVYAGSRANEFELRLQGVPYQTIAAQGGGILSTVNATRKASEEALIELALPR
CHHCCCEEEEEECCCCCEEEEEEECCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHH
LDGLLRSGVTSVEVKSGYGLTLKDELKMLRAAKALEQHRRVKITTTLLAAHALPPEFQGR
HHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCC
SDDYIAHICQEIIPRVAEEQLATSVDVFCESIGFSVAQTERVFHAAQAHGLQIKGHTEQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCHHHH
SNLGGSALTARMGGLSVDHIEYLDEAGVKALAQSSTVATLLPGAFYFLRETQKPPIEWLR
HHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHH
QYRVPMAISTDLNPGTSPFADLSLMMNMGCTLFDLTPEETLRAVTCHAAQALGYPANRGQ
HCCCCEEEECCCCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCC
IAEGYDADLAIWNIEHPAELSYQVGVSRLHARIVNGELSYES
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNCVLTEARLVTMQPGVQGYQITEPQTLIIEQGRIQHIGQHIDLPSDAHPISCAGKLVTP
CCCEEECCEEEEECCCCCCEEECCCCEEEEECCHHHHHHHHCCCCCCCCCCCCCCCCCCC
GLIDCHTHLVYAGSRANEFELRLQGVPYQTIAAQGGGILSTVNATRKASEEALIELALPR
CHHCCCEEEEEECCCCCEEEEEEECCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHH
LDGLLRSGVTSVEVKSGYGLTLKDELKMLRAAKALEQHRRVKITTTLLAAHALPPEFQGR
HHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCCCC
SDDYIAHICQEIIPRVAEEQLATSVDVFCESIGFSVAQTERVFHAAQAHGLQIKGHTEQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCHHHH
SNLGGSALTARMGGLSVDHIEYLDEAGVKALAQSSTVATLLPGAFYFLRETQKPPIEWLR
HHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHH
QYRVPMAISTDLNPGTSPFADLSLMMNMGCTLFDLTPEETLRAVTCHAAQALGYPANRGQ
HCCCCEEEECCCCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHCCCCCCCCC
IAEGYDADLAIWNIEHPAELSYQVGVSRLHARIVNGELSYES
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA