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The map label for this gene is trxB

Identifier: 227081354

GI number: 227081354

Start: 1213055

End: 1214011

Strand: Reverse

Name: trxB

Synonym: VCM66_1137

Alternate gene names: 227081354

Gene position: 1214011-1213055 (Counterclockwise)

Preceding gene: 227081358

Following gene: 227081353

Centisome position: 41.97

GC content: 50.47

Gene sequence:

>957_bases
ATGAGTAACGTGAAACACAGCAAACTTCTTATCCTTGGCTCCGGCCCTGCGGGTTACACAGCCGCGGTTTACGCTGCGCG
CGCCAACCTAAAACCCGTGCTGGTCACTGGTATGCAGCAAGGTGGTCAGCTCACCACGACGACAGAAGTCGAGAACTGGC
CAGGCGATGCCGAAGGCTTAACTGGCCCAGCACTGATGGAGCGCATGAAAGAGCACGCTGAGCGTTTCGATACTGAAATT
GTTTTTGATCACATTAACTCAGTTGATCTCTCTTCTCGCCCATTTCGTTTGACAGGCGACAGCCAAGAGTACACCTGTGA
TGCCCTCATCATCTCTACTGGTGCCTCTGCTAAATACCTCGGTTTAGAATCAGAAGAAGCGTTCAAAGGTCGCGGTGTAT
CCGCTTGTGCGACCTGTGATGGTTTCTTCTATCGCAACCAGAAAGTGGCAGTAGTCGGTGGTGGTAATACTGCGGTTGAA
GAGGCTCTTTACCTATCGAATATCGCCTCAGAAGTGCATCTGGTCCACCGCCGTGACAGCTTCCGCAGTGAAAAAATTCT
GATCGATCGTCTGATGGATAAAGTGGCGAATGGCAATATCGTTCTGCACACGCACCGCACTTTGGATGAAGTACTGGGCG
ATGAGATGGGCGTGACAGGCGTGCGTTTGAAAGATACCCAGTCAGATATGACGGAAAACTTGGATGTGATGGGGGTATTC
ATTGCCATTGGTCATCAGCCAAACTCGCAAATTTTCGAAGGTCAGCTTGAAATGAAAAACGGCTACATAGTCGTCAAATC
TGGCCTTGAAGGTAATGCAACCCAGACCAGCATTGAGGGTGTGTTTGCCGCGGGTGATGTGATGGATCATAACTACCGTC
AAGCGATTACCTCTGCCGGAACCGGGTGTATGGCAGCACTCGATGCTGAACGTTACCTAGATAGCCAGGGTAAATAA

Upstream 100 bases:

>100_bases
ATATTCCCTACAATCGAGTCCAATTATTTTCATTGGCTTGCGTCTTAGTTCCGAATTCAAGCCATGAGTTAACTCCCTTT
CGTCCTTATCGGAGTACTTC

Downstream 100 bases:

>100_bases
CTTACGCTTCGCGTAACGCCAGTTTTTATTTTTGCCAAGCCCGACGGGTATAACCGCCGGGCTTTTCTTTGTATACTGGC
GGCCTATTACAATTATTATT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGLTGPALMERMKEHAERFDTEI
VFDHINSVDLSSRPFRLTGDSQEYTCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIASEVHLVHRRDSFRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVF
IAIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDSQGK

Sequences:

>Translated_318_residues
MSNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGLTGPALMERMKEHAERFDTEI
VFDHINSVDLSSRPFRLTGDSQEYTCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVE
EALYLSNIASEVHLVHRRDSFRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVF
IAIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDSQGK
>Mature_317_residues
SNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGLTGPALMERMKEHAERFDTEIV
FDHINSVDLSSRPFRLTGDSQEYTCDALIISTGASAKYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEE
ALYLSNIASEVHLVHRRDSFRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVFI
AIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAGTGCMAALDAERYLDSQGK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=82.5396825396825, Blast_Score=549, Evalue=1e-157,
Organism=Escherichia coli, GI87081763, Length=314, Percent_Identity=32.1656050955414, Blast_Score=136, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6321898, Length=328, Percent_Identity=46.6463414634146, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6320560, Length=322, Percent_Identity=46.583850931677, Blast_Score=281, Evalue=8e-77,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRXB_VIBCH (Q9KSS4)

Other databases:

- EMBL:   AE003852
- PIR:   C82231
- RefSeq:   NP_230827.1
- ProteinModelPortal:   Q9KSS4
- SMR:   Q9KSS4
- GeneID:   2614615
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC1182
- TIGR:   VC_1182
- HOGENOM:   HBG669726
- OMA:   VMGAFIA
- ProtClustDB:   CLSK874247
- BRENDA:   1.8.1.9
- GO:   GO:0005737
- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- PRINTS:   PR00368
- PRINTS:   PR00469
- TIGRFAMs:   TIGR01292

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.8.1.9

Molecular weight: Translated: 34346; Mature: 34215

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGL
CCCCCCEEEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPALMERMKEHAERFDTEIVFDHINSVDLSSRPFRLTGDSQEYTCDALIISTGASAKYL
CCHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIASEVHLVHRRDS
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
FRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCCEEEEECCHHHHHCCCCEEEEE
IAIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAG
EEECCCCCCCEEECEEEECCCEEEEECCCCCCCCHHHHCEEEEECCHHCCHHHHHHHHCC
TGCMAALDAERYLDSQGK
CCCEEHHHHHHHHCCCCC
>Mature Secondary Structure 
SNVKHSKLLILGSGPAGYTAAVYAARANLKPVLVTGMQQGGQLTTTTEVENWPGDAEGL
CCCCCEEEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPALMERMKEHAERFDTEIVFDHINSVDLSSRPFRLTGDSQEYTCDALIISTGASAKYL
CCHHHHHHHHHHHHHHCHHHEECCCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVVGGGNTAVEEALYLSNIASEVHLVHRRDS
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCC
FRSEKILIDRLMDKVANGNIVLHTHRTLDEVLGDEMGVTGVRLKDTQSDMTENLDVMGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHCCCCCCCEEEEECCHHHHHCCCCEEEEE
IAIGHQPNSQIFEGQLEMKNGYIVVKSGLEGNATQTSIEGVFAAGDVMDHNYRQAITSAG
EEECCCCCCCEEECEEEECCCEEEEECCCCCCCCHHHHCEEEEECCHHCCHHHHHHHHCC
TGCMAALDAERYLDSQGK
CCCEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301