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The map label for this gene is rarA [H]

Identifier: 227081281

GI number: 227081281

Start: 1135115

End: 1136464

Strand: Direct

Name: rarA [H]

Synonym: VCM66_1064

Alternate gene names: 227081281

Gene position: 1135115-1136464 (Clockwise)

Preceding gene: 227081280

Following gene: 227081282

Centisome position: 39.24

GC content: 52.44

Gene sequence:

>1350_bases
GTGAGTAATTACAGCTTAGATTTTTCCGGCGACGAAGATTTTCGTCCGTTAGCTGCTCGTATGCGTCCACAAACGGTGGA
GCAGTATATTGGTCAGCAACACATCTTAGGGCCGGGAAAACCGCTGCGCCGTGCATTAGAAGCGGGGCATATTCACTCGA
TGATTCTTTGGGGACCTCCGGGCACCGGAAAAACCACTTTAGCCGAAGTGGCAGCCAACTACGCCAATGCGGAAGTGGAA
CGCGTATCGGCGGTGACGTCCGGAGTCAAAGAGATCCGTGCCGCGATCGAAAAAGCGCGTGAGAACAAACTCAGTGGTCG
ACGCACTATTCTGTTTGTCGACGAAGTCCATCGCTTTAATAAATCGCAGCAAGATGCGTTTTTGCCGCATATTGAAGATG
GTACGGTCACTTTTATTGGCGCAACCACGGAGAACCCTTCTTTTGAGCTTAATAACGCGCTGCTTTCCCGCGCGCGGGTT
TATAAGCTCACCTCACTCAATCAACAAGAAATTCTGCAAGCTCTGCATCAAGCGATTGCCGATACTGAACGCGGGCTTGG
CAAAGTGGCGGCGGTATTTGCTGATAATGTTTTAGATCGCCTAGCCGAACTGGTCAATGGCGATGCGCGCATGTCGCTCA
ATTATCTTGAACTGCTGTACGACATGGCTCGCGAAGATGATCAGGGACGCAAGCAGATTGATCTGCCTTTATTGGCTGAA
GTCGCTGGTGAAAAAGTGTCGCGCTTTGATAACAAGGGCGATATTTGGTATGACCTGATTTCCGCTGTACACAAATCGAT
TCGAGGTTCCGATCCCGATGCAGCGCTGTACTGGGCGGCGCGGATGATTTCCGCAGGCTGTGACCCTTTGTATATCGCGC
GCCGTCTGCTCGCGATTGCCTCTGAAGATGTTGGTAATGCCGACCCACGGGGCATGCAAGTGGCACTCGCAGCGTGGGAT
TGCTTTACCCGTGTGGGGCCTGCAGAAGGCGAGCGCGCGATTGCTCAAGCGATTGTCTACCTCGCCTGCGCACCGAAAAG
CAACGCGGTGTACACCGCGTGGAAACAAGCGCTGTCGGATGCGCATAATCTGCCTGAGTTTGAAGTACCGCCGCATCTGC
GTAATGCCCCAACGCGATTGATGAAAGATCTCGGTTATGGTGAGGAATACCGTTACGCCCATGATGAACCGGGCGCTTAT
GCTGCAGGGGAGTGCTATTTCCCACCAGAAATGAGTGGAACTCGCTACTATCAGCCTACTCCACGCGGGCTAGAAACTAA
GATTGCCGAAAAGTTAGCGTATCTGGCGGATTTGAACGCAAAAAGCCCACAAAAGCGCTATGAAAAGTAG

Upstream 100 bases:

>100_bases
ACAGCAGAAACCAAACGCTAGCGTATTTAACTACAAAGTGCCGAAAGGCGTGGAAGTTGACGATCAGCGTAACTAAATCA
GCACCAAGGAAGCGAGTCGA

Downstream 100 bases:

>100_bases
TGCCTTTTGGTTATCTTTGGCAGGGTAAATTTCAATACGCGTGGCTTTGGCTAAAAAGGAAGCACACGCGCTTTCTCGCA
ACTCTTAAAGCATAGGATTA

Product: recombination factor protein RarA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAEVE
RVSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARV
YKLTSLNQQEILQALHQAIADTERGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAE
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIASEDVGNADPRGMQVALAAWD
CFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAY
AAGECYFPPEMSGTRYYQPTPRGLETKIAEKLAYLADLNAKSPQKRYEK

Sequences:

>Translated_449_residues
MSNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAEVE
RVSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARV
YKLTSLNQQEILQALHQAIADTERGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAE
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIASEDVGNADPRGMQVALAAWD
CFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAY
AAGECYFPPEMSGTRYYQPTPRGLETKIAEKLAYLADLNAKSPQKRYEK
>Mature_448_residues
SNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPPGTGKTTLAEVAANYANAEVER
VSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFNKSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVY
KLTSLNQQEILQALHQAIADTERGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAEV
AGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIASEDVGNADPRGMQVALAAWDC
FTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSDAHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAYA
AGECYFPPEMSGTRYYQPTPRGLETKIAEKLAYLADLNAKSPQKRYEK

Specific function: Unknown

COG id: COG2256

COG function: function code L; ATPase related to the helicase subunit of the Holliday junction resolvase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rarA family [H]

Homologues:

Organism=Homo sapiens, GI18426902, Length=441, Percent_Identity=42.6303854875283, Blast_Score=313, Evalue=2e-85,
Organism=Homo sapiens, GI18426904, Length=441, Percent_Identity=38.3219954648526, Blast_Score=255, Evalue=6e-68,
Organism=Escherichia coli, GI1787119, Length=447, Percent_Identity=73.6017897091723, Blast_Score=676, Evalue=0.0,
Organism=Escherichia coli, GI1786676, Length=288, Percent_Identity=24.6527777777778, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324111, Length=426, Percent_Identity=41.0798122065728, Blast_Score=316, Evalue=4e-87,
Organism=Saccharomyces cerevisiae, GI6324039, Length=210, Percent_Identity=26.1904761904762, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR021886 [H]

Pfam domain/function: PF00004 AAA; PF12002 MgsA_C [H]

EC number: NA

Molecular weight: Translated: 49784; Mature: 49653

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPP
CCCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEEECCC
GTGKTTLAEVAANYANAEVERVSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCC
KSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLTSLNQQEILQALHQAIA
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DTERGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHH
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIA
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
SEDVGNADPRGMQVALAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSD
HCCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAYAAGECYFPPEMSGTRYYQPT
HHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEECCC
PRGLETKIAEKLAYLADLNAKSPQKRYEK
CCCHHHHHHHHHHHHHHCCCCCCHHHCCC
>Mature Secondary Structure 
SNYSLDFSGDEDFRPLAARMRPQTVEQYIGQQHILGPGKPLRRALEAGHIHSMILWGPP
CCCCCCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCCHHHHHHHHHCCEEEEEEECCC
GTGKTTLAEVAANYANAEVERVSAVTSGVKEIRAAIEKARENKLSGRRTILFVDEVHRFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCC
KSQQDAFLPHIEDGTVTFIGATTENPSFELNNALLSRARVYKLTSLNQQEILQALHQAIA
CCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
DTERGLGKVAAVFADNVLDRLAELVNGDARMSLNYLELLYDMAREDDQGRKQIDLPLLAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHCCCHHHHH
VAGEKVSRFDNKGDIWYDLISAVHKSIRGSDPDAALYWAARMISAGCDPLYIARRLLAIA
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
SEDVGNADPRGMQVALAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAWKQALSD
HCCCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AHNLPEFEVPPHLRNAPTRLMKDLGYGEEYRYAHDEPGAYAAGECYFPPEMSGTRYYQPT
HHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCEEECCC
PRGLETKIAEKLAYLADLNAKSPQKRYEK
CCCHHHHHHHHHHHHHHCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]