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The map label for this gene is dnaZX [H]

Identifier: 227081227

GI number: 227081227

Start: 1080126

End: 1082204

Strand: Direct

Name: dnaZX [H]

Synonym: VCM66_1009

Alternate gene names: 227081227

Gene position: 1080126-1082204 (Clockwise)

Preceding gene: 227081226

Following gene: 227081228

Centisome position: 37.34

GC content: 51.56

Gene sequence:

>2079_bases
ATGAGTTATCTTGCTTTAGCACGCAAATGGCGTCCGACACGATTTAGCGAAGTGGTCGGACAATCCCATGTTTTAACCGC
TTTAGAGAACGCTTTGGCGCAAAACCGTTTGCACCATGCGTACTTGTTTAGTGGCACTCGAGGCGTGGGTAAGACCACCA
TAGGTCGTTTGTTTGCGAAGGGGCTCAACTGCGAGACGGGCATAACGGCTACGCCTTGCGGCCAGTGTGCAACCTGTCAA
GAAATTGATCAGGGACGCTTTGTGGATCTGCTCGAGATTGACGCTGCATCACGCACCAAAGTGGAAGATACGCGCGAGCT
ACTCGACAACGTGCAGTACAAACCTGCGCGTGGACGCTTCAAAGTTTACCTGATCGATGAAGTTCATATGCTCTCGCGTC
ACAGCTTCAATGCGCTACTGAAAACGCTTGAAGAGCCGCCTGAGTATGTGAAGTTTTTGCTGGCAACCACTGATCCACAA
AAGCTGCCTGTGACCATCTTGTCTCGCTGTTTGCAGTTCCATCTCAAACCGATCAGTGTAGAAAATATCCAGCAGCAGCT
CGATAAAGTGCTGCACGCCGAACAGATTTCGAGCGACAGCAAAGCACTCAATCTGCTCGCCCACGCTGCGGATGGCAGTA
TGCGCGATGCTCTTAGCTTGACCGATCAAGCGATTGCTTTGGGCAATGGCGTAGTGAAAAGTGACATCGTCGCGCACATG
CTCGGCACATTAGATACGGATCATTCTCTACATCTCTTGCAAGCCATCAGCCTGCAAACGCCACAAGCAGTCATGGATTG
CATCGAAACACTTGCCCAAAATGGCGTAGAGTGGGATGGATTACTGCAACAGCTTTCGACTCAACTGCATCGAATTGCTA
TGTACCAAGCGTTGCCTGCCACCTTGGATAAATCGCTGCCAGAGGCATCGCGTATTGAGTCGTTGGCCAAAACCTTAGCG
CCGCAAGATGTGCAGCTTTACTACCAAATTGCGCTCAAAGGTCGACAAGATTTACCACTGTCACCCACGGCGCGAATTGG
CATTGAAATGTTGATGCTGCGTATGATGGCGTTTCGTCCTTCTCACGTCTCCTTGGCGAGTGTGATTGTGCCACCCAATA
CGGCAGTGACAGCTCCAACAATCGCGGCACCGACTTCTCAAATGGCGGCTGCAGCGCCGCAACCACAACCCGTTGCTCAG
TCAAACGTATCGCAATCTGCCTCGCAAGCGATGCCTCACCCTGTCGCACCGCCAATGATGGCAGCACAGCCAGTGGTAGA
AAGCGCGGTGCCAGTCACTCAGCGAGAAGCATCACACTCAATAAACGCTCCAGAAGCCTCTGTTGTCACCAATACCGACA
CGCAGAGTCAAGCCAGCATGCCAGCCCTAGCAGGGCTGCGTCATCAACTGCGCTCTAAGCGACAAGAAGTACAAAACAAA
GGCGCGGATGGAAAAAAGTCTGACGCGACATCTGCTACTCCAGCATCGGCGCTAGAGCGTATTGCGCAGAGAGCACAGCA
AGTGCAGGTGTCGCCAGAACGCAATGATGAAGATGAGTTGGAGCCTGAAGAGGAAATCTATCAATGGCGTCCGATGCAAC
CTATCGAAGTCGCGGTAAAAAGTGAAGTCACGCCAACGCAACTGAAAAAAGCGTTAGAGCATGAAAAAACGCCGGAAATG
GGAGCGAAGTTGATTGAAGAAGCGGTCGCGCAAGACGCGTGGTCGGCATTGGTTCAACGGCTAGAGACTGCCAAAATGGT
TGAGCAATTGGCGCTGAATTCCGCTTTTGTTCGTCAAGGCGATCAGATTTCTCTGACGCTGCGTCCAAGTCATGCCCATC
TGCACAACGAAAAAGCGCAGCAAGAGTTAGAACAGGCATTGAATCATGTGCTTGGTGAAGCTTGTTCATTGAACATTACC
GTGGGACAAGAGGGAGAAACCCCCCTTGAGCTGCGTGAACGGCTCTACCAGCAGAAACTCACTTCTGCGCTGCACAGTTT
ACAAACTGATCCCAACGTGCAGTTTATTGAGCGTCGATTTAATGCACAGCTCGATAGCGACAGCGTACGACCCATTTAA

Upstream 100 bases:

>100_bases
CTTGCCAGAAATTGGTGGTGATAAGCGCCTTGAAGGGTTAGGCTTGCAGGTTTACAGCATCTGTGAATTTGAAGGTCACT
AACCGACAACGGATATTGGA

Downstream 100 bases:

>100_bases
CTGGGGTTGAAACCTAAGTGTCTCACCCCCACACTATGTGAAACATTCAACGATAACCAGAGAGATAAAGATGTTTGGTA
AAGGCGGAATGGGCAACCTG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MSYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAKGLNCETGITATPCGQCATCQ
EIDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQ
KLPVTILSRCLQFHLKPISVENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVAHM
LGTLDTDHSLHLLQAISLQTPQAVMDCIETLAQNGVEWDGLLQQLSTQLHRIAMYQALPATLDKSLPEASRIESLAKTLA
PQDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRPSHVSLASVIVPPNTAVTAPTIAAPTSQMAAAAPQPQPVAQ
SNVSQSASQAMPHPVAPPMMAAQPVVESAVPVTQREASHSINAPEASVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNK
GADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVKSEVTPTQLKKALEHEKTPEM
GAKLIEEAVAQDAWSALVQRLETAKMVEQLALNSAFVRQGDQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNIT
VGQEGETPLELRERLYQQKLTSALHSLQTDPNVQFIERRFNAQLDSDSVRPI

Sequences:

>Translated_692_residues
MSYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAKGLNCETGITATPCGQCATCQ
EIDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQ
KLPVTILSRCLQFHLKPISVENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVAHM
LGTLDTDHSLHLLQAISLQTPQAVMDCIETLAQNGVEWDGLLQQLSTQLHRIAMYQALPATLDKSLPEASRIESLAKTLA
PQDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRPSHVSLASVIVPPNTAVTAPTIAAPTSQMAAAAPQPQPVAQ
SNVSQSASQAMPHPVAPPMMAAQPVVESAVPVTQREASHSINAPEASVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNK
GADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVKSEVTPTQLKKALEHEKTPEM
GAKLIEEAVAQDAWSALVQRLETAKMVEQLALNSAFVRQGDQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNIT
VGQEGETPLELRERLYQQKLTSALHSLQTDPNVQFIERRFNAQLDSDSVRPI
>Mature_691_residues
SYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAKGLNCETGITATPCGQCATCQE
IDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQK
LPVTILSRCLQFHLKPISVENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVAHML
GTLDTDHSLHLLQAISLQTPQAVMDCIETLAQNGVEWDGLLQQLSTQLHRIAMYQALPATLDKSLPEASRIESLAKTLAP
QDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRPSHVSLASVIVPPNTAVTAPTIAAPTSQMAAAAPQPQPVAQS
NVSQSASQAMPHPVAPPMMAAQPVVESAVPVTQREASHSINAPEASVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNKG
ADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVKSEVTPTQLKKALEHEKTPEMG
AKLIEEAVAQDAWSALVQRLETAKMVEQLALNSAFVRQGDQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNITV
GQEGETPLELRERLYQQKLTSALHSLQTDPNVQFIERRFNAQLDSDSVRPI

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=700, Percent_Identity=49.7142857142857, Blast_Score=603, Evalue=1e-174,
Organism=Escherichia coli, GI1787341, Length=146, Percent_Identity=31.5068493150685, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71986063, Length=312, Percent_Identity=21.7948717948718, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324039, Length=228, Percent_Identity=25.4385964912281, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 76028; Mature: 75896

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAK
CCHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHC
GLNCETGITATPCGQCATCQEIDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRF
CCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
KVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQKLPVTILSRCLQFHLKPISV
EEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCH
ENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVAHM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGTLDTDHSLHLLQAISLQTPQAVMDCIETLAQNGVEWDGLLQQLSTQLHRIAMYQALPA
HHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TLDKSLPEASRIESLAKTLAPQDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRP
HHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
SHVSLASVIVPPNTAVTAPTIAAPTSQMAAAAPQPQPVAQSNVSQSASQAMPHPVAPPMM
CCCCEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
AAQPVVESAVPVTQREASHSINAPEASVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNK
HHHHHHHHCCCCHHHHHCCCCCCCCCCEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHC
GADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVK
CCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHHH
SEVTPTQLKKALEHEKTPEMGAKLIEEAVAQDAWSALVQRLETAKMVEQLALNSAFVRQG
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNITVGQEGETPLELRERLYQQKL
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHH
TSALHSLQTDPNVQFIERRFNAQLDSDSVRPI
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SYLALARKWRPTRFSEVVGQSHVLTALENALAQNRLHHAYLFSGTRGVGKTTIGRLFAK
CHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHC
GLNCETGITATPCGQCATCQEIDQGRFVDLLEIDAASRTKVEDTRELLDNVQYKPARGRF
CCCCCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCE
KVYLIDEVHMLSRHSFNALLKTLEEPPEYVKFLLATTDPQKLPVTILSRCLQFHLKPISV
EEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCH
ENIQQQLDKVLHAEQISSDSKALNLLAHAADGSMRDALSLTDQAIALGNGVVKSDIVAHM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGTLDTDHSLHLLQAISLQTPQAVMDCIETLAQNGVEWDGLLQQLSTQLHRIAMYQALPA
HHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
TLDKSLPEASRIESLAKTLAPQDVQLYYQIALKGRQDLPLSPTARIGIEMLMLRMMAFRP
HHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
SHVSLASVIVPPNTAVTAPTIAAPTSQMAAAAPQPQPVAQSNVSQSASQAMPHPVAPPMM
CCCCEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
AAQPVVESAVPVTQREASHSINAPEASVVTNTDTQSQASMPALAGLRHQLRSKRQEVQNK
HHHHHHHHCCCCHHHHHCCCCCCCCCCEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHC
GADGKKSDATSATPASALERIAQRAQQVQVSPERNDEDELEPEEEIYQWRPMQPIEVAVK
CCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHCCCCCHHHHHHH
SEVTPTQLKKALEHEKTPEMGAKLIEEAVAQDAWSALVQRLETAKMVEQLALNSAFVRQG
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DQISLTLRPSHAHLHNEKAQQELEQALNHVLGEACSLNITVGQEGETPLELRERLYQQKL
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEECCCCCCHHHHHHHHHHHHH
TSALHSLQTDPNVQFIERRFNAQLDSDSVRPI
HHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]