Click here to switch to the map view.

The map label for this gene is accD

Identifier: 227081174

GI number: 227081174

Start: 1028368

End: 1029294

Strand: Direct

Name: accD

Synonym: VCM66_0956

Alternate gene names: 227081174

Gene position: 1028368-1029294 (Clockwise)

Preceding gene: 227081173

Following gene: 227081175

Centisome position: 35.55

GC content: 49.84

Gene sequence:

>927_bases
ATGAGTTGGCTCGAAAAGATTTTAGAGAAAAGCAACATCGTCAGTTCACGCAAAGCCTCTATCCCAGAAGGCGTTTGGAC
TAAATGTACATCGTGTGAACAAGTGCTTTATTACGCGGAGTTGGAGCGTAACCTAGAAGTTTGTCCTAAGTGTGATCATC
ACATGCGCATGAAAGCACGTCGCCGTTTGGAAACGTTTCTGGATCAAGGTGAGCGTGTTGAGCTGGGTGAAGAGCTCGAG
CCACAAGACAAACTGAAATTTAAAGATTCTAAACGCTACAAAGAGCGTCTTGCTGCGGCGCAAAAAGCCAGTGGTGAGAA
GGATGCTCTGGTCGTCATGAAAGGTGCTGTGCTTGGTGTTCCTGTCGTGGCGTGTGCCTTTGAGTTCTCTTTTATGGGCG
GCTCAATGGGTTCTGTGGTTGGTGCTCGTTTTGTGCGTGCGGTTGAAGCGGCGATTGAACACAACTGCGGATTAATCTGT
TTCTCTGCCAGCGGCGGTGCGCGTATGCAAGAGGCATTAATGTCTCTGATGCAAATGGCCAAAACCAGTGCCGCGCTAGA
GCGTTTATCGGATAAAGGCTTGCCTTTCATTTCCGTGATGACCGACCCAACTATGGGCGGGGTGTCAGCGAGTTTGGCGA
TGCTGGGCGATATTAATATCGGTGAGCCCAAAGCATTGATCGGTTTTGCAGGTCGTCGCGTTATTGAGCAAACCGTACGT
GAAGAGCTTCCGGAAGGTTTCCAACGCAGTGAGTTCCTGCTAGAGCATGGTGCGATTGATATGATCGTTGATCGCCGAGA
CATGCGTCAGCGTGTCGCTAGCTTACTGGCGAAAATGACTGGCCAAGCGTCTCCTCTCGTAGTTTCTGTGAACGACGCGC
CAAATGAAGTGCCTTATGCGGTACCAGAAGCCAATAAAAAAGGGTAA

Upstream 100 bases:

>100_bases
TTGTCTACAGTTGGCATTTTCTGTGTTTTAATCCACACGCATTTTTTGTCGAATTTATCTCTCCTGCTGATGGCGGGAGA
TTGAGAGTAAAAGGTCTTCC

Downstream 100 bases:

>100_bases
AGTAAGCGCTAACTAAACCAACGGATTCTATGGTTGTACGTTAGATGACTCAAAAGCCTGTTCCTCAAGCCACATCTCCA
CTCGCGGTGTGGCTTGATTA

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSWLEKILEKSNIVSSRKASIPEGVWTKCTSCEQVLYYAELERNLEVCPKCDHHMRMKARRRLETFLDQGERVELGEELE
PQDKLKFKDSKRYKERLAAAQKASGEKDALVVMKGAVLGVPVVACAFEFSFMGGSMGSVVGARFVRAVEAAIEHNCGLIC
FSASGGARMQEALMSLMQMAKTSAALERLSDKGLPFISVMTDPTMGGVSASLAMLGDINIGEPKALIGFAGRRVIEQTVR
EELPEGFQRSEFLLEHGAIDMIVDRRDMRQRVASLLAKMTGQASPLVVSVNDAPNEVPYAVPEANKKG

Sequences:

>Translated_308_residues
MSWLEKILEKSNIVSSRKASIPEGVWTKCTSCEQVLYYAELERNLEVCPKCDHHMRMKARRRLETFLDQGERVELGEELE
PQDKLKFKDSKRYKERLAAAQKASGEKDALVVMKGAVLGVPVVACAFEFSFMGGSMGSVVGARFVRAVEAAIEHNCGLIC
FSASGGARMQEALMSLMQMAKTSAALERLSDKGLPFISVMTDPTMGGVSASLAMLGDINIGEPKALIGFAGRRVIEQTVR
EELPEGFQRSEFLLEHGAIDMIVDRRDMRQRVASLLAKMTGQASPLVVSVNDAPNEVPYAVPEANKKG
>Mature_307_residues
SWLEKILEKSNIVSSRKASIPEGVWTKCTSCEQVLYYAELERNLEVCPKCDHHMRMKARRRLETFLDQGERVELGEELEP
QDKLKFKDSKRYKERLAAAQKASGEKDALVVMKGAVLGVPVVACAFEFSFMGGSMGSVVGARFVRAVEAAIEHNCGLICF
SASGGARMQEALMSLMQMAKTSAALERLSDKGLPFISVMTDPTMGGVSASLAMLGDINIGEPKALIGFAGRRVIEQTVRE
ELPEGFQRSEFLLEHGAIDMIVDRRDMRQRVASLLAKMTGQASPLVVSVNDAPNEVPYAVPEANKKG

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=310, Percent_Identity=73.2258064516129, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_VIBCH (Q9KTA3)

Other databases:

- EMBL:   AE003852
- PIR:   B82253
- RefSeq:   NP_230646.1
- HSSP:   Q8GBW6
- ProteinModelPortal:   Q9KTA3
- SMR:   Q9KTA3
- GeneID:   2614253
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC1000
- TIGR:   VC_1000
- HOGENOM:   HBG285696
- OMA:   LEHGMVD
- ProtClustDB:   PRK05654
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 33806; Mature: 33674

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLEKILEKSNIVSSRKASIPEGVWTKCTSCEQVLYYAELERNLEVCPKCDHHMRMKAR
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RRLETFLDQGERVELGEELEPQDKLKFKDSKRYKERLAAAQKASGEKDALVVMKGAVLGV
HHHHHHHCCCCEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHH
PVVACAFEFSFMGGSMGSVVGARFVRAVEAAIEHNCGLICFSASGGARMQEALMSLMQMA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
KTSAALERLSDKGLPFISVMTDPTMGGVSASLAMLGDINIGEPKALIGFAGRRVIEQTVR
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EELPEGFQRSEFLLEHGAIDMIVDRRDMRQRVASLLAKMTGQASPLVVSVNDAPNEVPYA
HHHHCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
VPEANKKG
CCCCCCCC
>Mature Secondary Structure 
SWLEKILEKSNIVSSRKASIPEGVWTKCTSCEQVLYYAELERNLEVCPKCDHHMRMKAR
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
RRLETFLDQGERVELGEELEPQDKLKFKDSKRYKERLAAAQKASGEKDALVVMKGAVLGV
HHHHHHHCCCCEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHH
PVVACAFEFSFMGGSMGSVVGARFVRAVEAAIEHNCGLICFSASGGARMQEALMSLMQMA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
KTSAALERLSDKGLPFISVMTDPTMGGVSASLAMLGDINIGEPKALIGFAGRRVIEQTVR
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
EELPEGFQRSEFLLEHGAIDMIVDRRDMRQRVASLLAKMTGQASPLVVSVNDAPNEVPYA
HHHHCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCC
VPEANKKG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301