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The map label for this gene is corC

Identifier: 227081133

GI number: 227081133

Start: 981033

End: 981908

Strand: Reverse

Name: corC

Synonym: VCM66_0915

Alternate gene names: 227081133

Gene position: 981908-981033 (Counterclockwise)

Preceding gene: 227081134

Following gene: 227081132

Centisome position: 33.95

GC content: 49.77

Gene sequence:

>876_bases
ATGAACGAAGACAATTCTCAGAATTCGGAAGGTCCGAGTAGAAAGTCCTTCTTTGAACGCCTAAGTCAACTTTTTCAGGG
AGAGCCGAAAGATCGCCAAGAGCTGGTCGATGTAATTCGCGACTCTGAAGTCAATGACTTGATTGACCATGACACCCGCG
ACATGCTCGAAGGTGTGATGGAAATCGCCGAAATGCGCGTGCGCGATATCATGATCCCACGCTCACAAATGGTCACTATC
GATCGTACTCATAACCTAGATGCTTTGGTTGCCATCATGACTGATGCGCAGCACTCACGTTATCCAGTGATCAGCGAAGA
TAAAGACCATGTGGAAGGCATTCTGCTTGCGAAGGACTTACTCAAATATCTAGGCTCTAACTGTGCCCCATTCAACATCC
AAGAAGTGATCCGTCCTGCGGTCGTGGTTCCGGAAAGCAAGCGGGTTGACCGTCTGCTCAAAGAATTCCGTGAAGAACGT
TACCACATGGCAATTGTGGTGGATGAGTTTGGCGGCGTATCAGGCCTAGTCACCATTGAAGATATTCTGGAAGAGATCGT
CGGCGACATCGAAGATGAATTCGACGACGAAGAGCAAAAAGACATTCGCCAACTGAGCAAACACACCTTTTCGGTGAAAG
CGCTCACCACAATTGAAGACTTTAACCACACTTTCGGCACCAAATTCAGTGATGAAGAAGTGGATACGGTCGGTGGTTTG
GTGATGACGGCATTCGGCCACTTACCCGCGCGCGGTGAAGTCGTAGACATTGCAGGCTACAACTTCAAAGTGACAGCGGC
GGATAGTCGCCGAGTGGTGGCTCTTCAAGTGACCGTTCCCGATCTGGAAGCCCTTTCGCACGTTGCGGAAGAGTAG

Upstream 100 bases:

>100_bases
TACCGACCCATATCTGGCAGAAAAAGAGTAACCCTTATCCTTTTAGATAAGGCCTATGTGAGCTATCACACATCTGATAG
CGTTAGTGAATTGAGACATA

Downstream 100 bases:

>100_bases
TCCCCACTCTCTTACTAAGTAAGAGTAAAGAAAAGAGACGATGAACAGCGTATTATCTCATCGCCTAATGCGGCCGCTTG
CGGCCGCTTTTGTTGGCGTC

Product: putative hemolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNEDNSQNSEGPSRKSFFERLSQLFQGEPKDRQELVDVIRDSEVNDLIDHDTRDMLEGVMEIAEMRVRDIMIPRSQMVTI
DRTHNLDALVAIMTDAQHSRYPVISEDKDHVEGILLAKDLLKYLGSNCAPFNIQEVIRPAVVVPESKRVDRLLKEFREER
YHMAIVVDEFGGVSGLVTIEDILEEIVGDIEDEFDDEEQKDIRQLSKHTFSVKALTTIEDFNHTFGTKFSDEEVDTVGGL
VMTAFGHLPARGEVVDIAGYNFKVTAADSRRVVALQVTVPDLEALSHVAEE

Sequences:

>Translated_291_residues
MNEDNSQNSEGPSRKSFFERLSQLFQGEPKDRQELVDVIRDSEVNDLIDHDTRDMLEGVMEIAEMRVRDIMIPRSQMVTI
DRTHNLDALVAIMTDAQHSRYPVISEDKDHVEGILLAKDLLKYLGSNCAPFNIQEVIRPAVVVPESKRVDRLLKEFREER
YHMAIVVDEFGGVSGLVTIEDILEEIVGDIEDEFDDEEQKDIRQLSKHTFSVKALTTIEDFNHTFGTKFSDEEVDTVGGL
VMTAFGHLPARGEVVDIAGYNFKVTAADSRRVVALQVTVPDLEALSHVAEE
>Mature_291_residues
MNEDNSQNSEGPSRKSFFERLSQLFQGEPKDRQELVDVIRDSEVNDLIDHDTRDMLEGVMEIAEMRVRDIMIPRSQMVTI
DRTHNLDALVAIMTDAQHSRYPVISEDKDHVEGILLAKDLLKYLGSNCAPFNIQEVIRPAVVVPESKRVDRLLKEFREER
YHMAIVVDEFGGVSGLVTIEDILEEIVGDIEDEFDDEEQKDIRQLSKHTFSVKALTTIEDFNHTFGTKFSDEEVDTVGGL
VMTAFGHLPARGEVVDIAGYNFKVTAADSRRVVALQVTVPDLEALSHVAEE

Specific function: Plays a role in the transport of magnesium and cobalt ions

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains

Homologues:

Organism=Homo sapiens, GI310128564, Length=206, Percent_Identity=33.9805825242718, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI94681046, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40068055, Length=183, Percent_Identity=27.8688524590164, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI40068053, Length=183, Percent_Identity=27.8688524590164, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786879, Length=283, Percent_Identity=66.7844522968198, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI87082033, Length=270, Percent_Identity=27.037037037037, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI145693175, Length=236, Percent_Identity=25.8474576271186, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788119, Length=224, Percent_Identity=33.0357142857143, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790664, Length=234, Percent_Identity=27.3504273504274, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CORC_VIBCH (Q9KTE3)

Other databases:

- EMBL:   AE003852
- PIR:   B82261
- RefSeq:   NP_230606.1
- ProteinModelPortal:   Q9KTE3
- GeneID:   2614212
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC0959
- TIGR:   VC_0959
- HOGENOM:   HBG673071
- OMA:   QMISIKA
- ProtClustDB:   CLSK874163
- GO:   GO:0006810
- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170
- Gene3D:   G3DSA:3.30.465.10
- SMART:   SM00116

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC

EC number: NA

Molecular weight: Translated: 32916; Mature: 32916

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS51371 CBS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEDNSQNSEGPSRKSFFERLSQLFQGEPKDRQELVDVIRDSEVNDLIDHDTRDMLEGVM
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHH
EIAEMRVRDIMIPRSQMVTIDRTHNLDALVAIMTDAQHSRYPVISEDKDHVEGILLAKDL
HHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LKYLGSNCAPFNIQEVIRPAVVVPESKRVDRLLKEFREERYHMAIVVDEFGGVSGLVTIE
HHHHCCCCCCCCHHHHHCCCEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHH
DILEEIVGDIEDEFDDEEQKDIRQLSKHTFSVKALTTIEDFNHTFGTKFSDEEVDTVGGL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCHHHHHHHH
VMTAFGHLPARGEVVDIAGYNFKVTAADSRRVVALQVTVPDLEALSHVAEE
HHHHHCCCCCCCCEEEECCCEEEEEECCCCEEEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MNEDNSQNSEGPSRKSFFERLSQLFQGEPKDRQELVDVIRDSEVNDLIDHDTRDMLEGVM
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHH
EIAEMRVRDIMIPRSQMVTIDRTHNLDALVAIMTDAQHSRYPVISEDKDHVEGILLAKDL
HHHHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LKYLGSNCAPFNIQEVIRPAVVVPESKRVDRLLKEFREERYHMAIVVDEFGGVSGLVTIE
HHHHCCCCCCCCHHHHHCCCEECCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEEHH
DILEEIVGDIEDEFDDEEQKDIRQLSKHTFSVKALTTIEDFNHTFGTKFSDEEVDTVGGL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCCCHHHHHHHH
VMTAFGHLPARGEVVDIAGYNFKVTAADSRRVVALQVTVPDLEALSHVAEE
HHHHHCCCCCCCCEEEECCCEEEEEECCCCEEEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301