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The map label for this gene is lnt

Identifier: 227081132

GI number: 227081132

Start: 979475

End: 980992

Strand: Reverse

Name: lnt

Synonym: VCM66_0914

Alternate gene names: 227081132

Gene position: 980992-979475 (Counterclockwise)

Preceding gene: 227081133

Following gene: 227081130

Centisome position: 33.91

GC content: 51.19

Gene sequence:

>1518_bases
ATGAACAGCGTATTATCTCATCGCCTAATGCGGCCGCTTGCGGCCGCTTTTGTTGGCGTCATAACTCCTCTGGCTTTTGC
CCCGTATCAATTTTGGCCTTTGGCTCTACTCAGCCCATTTATCCTACTGCTTCTGCTCCACCAACAAAGCGCCAAGCGAG
CGGCTTTGATTGCTTATCTCTGGGGGATTGGTCAATTTGCGGTGGGTATCAGTTGGGTACACGTCAGTATTGATACGTTT
GGCGGCATGCCCAAAATCGCTAGCCTGTTTTTAATGACTCTATTGGTCGGCTATCTGGCGCTTTATCCAAGCCTTTTCGG
CTGGCTACTTAATCGCTTGTTTCCGAACAACTCACGCAGTAAATGGTTATGTGCTGCCCCAGCTTTGTGGCTGATTACCG
ATTGGCTACGTGGTTGGGTGATGACGGGTTTTCCTTGGCTGTGGCTCGGTTATAGCCAAATTGATAGCCCTCTCGCCAAC
TTTGCCCCTATCGGTGGCGTAGAGCTCATCACGCTGTTATTGCTGTTTTGTGCTGGTAGCTTAGCTTATGCCGTACTTAA
TCGCCGTTGGCTGATGGCTTGCATCCCTCTTGTGGTTTACGCAACCGGTTATGGCCTCCAAGCCATGCAGTGGGTCACCC
CACAAACTGAGCGCACAGCCTCACTGGCCTTGATTCAAGGCAATATCGAACAGGGATTGAAATGGCTGCCTAGCCAGCGC
TGGCCAACCATCATGAAATACACCGATCTTACTCGCGAAAACTGGGATGCCGATGTGATCATTTGGCCAGAAGCGGCGAT
CCCCGCTTTTGAATATGAAATCTCCTCATTTCTGCATAATCTTGATGCTGCGGCACGTATGAACCAAAGCGCGGTGATTA
CTGGCATCATCAATCAAAGTGATGATAAGCAGTACTTCAATAGCGTGCTGACCGTCGGTGATACGCCTCATGGCGAATAC
CGTTATGATCTGACTCAGCGCTACCATAAGTACCACTTGTTGCCTTTTGGCGAATTCGTGCCGTTTGAAGAGATCCTGCG
TCCATTAGCTCCATTCTTTAATTTGCCGATGTCCTCCTTTAGCCAAGGGGCTTACGTGCAACCGAATTTGATTGCAAAGG
GTTTCGCATTTGTCACCGCACTCTGCTACGAAATCATCTTCAATGAGCAGGTACGCGATAATGTGACGCCAGACACCGAC
TTCCTACTGACGCTTTCGAATGATGCTTGGTTTGGTCGTTCGATAGGCCCATTGCAACACATGGAAATCGCTCGCATGCG
CGCCTTAGAATTGGGCAAGCCGCTGATCCGCGCCACCAACAATGGAGTGACGGCCGTCACCGATGAGCGTGGACGCATTA
TGGCTCAGCTGCCACAATTCGAAACTGGCGTGCTAAAAGCAACGGTCACCCCGACTCGCGGTAGTACACCTTACTTCCTA
TGGGGCACAACGCCACTCTACCTTTGGGTAGGCTTAGCGGCTGGGTTCGCTTTCTGGCGCCAGCGCCGGGCTAGATAA

Upstream 100 bases:

>100_bases
GTGGCTCTTCAAGTGACCGTTCCCGATCTGGAAGCCCTTTCGCACGTTGCGGAAGAGTAGTCCCCACTCTCTTACTAAGT
AAGAGTAAAGAAAAGAGACG

Downstream 100 bases:

>100_bases
GTAAAAACAAAACGGGAAGTTATCTTCCCGTTTTTTATTGCAGCGCTTTATCCAACTAAGGTTTCAGTGGTTGGCGGCTA
AACGCTTTACCGCCACATTG

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MNSVLSHRLMRPLAAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYLWGIGQFAVGISWVHVSIDTF
GGMPKIASLFLMTLLVGYLALYPSLFGWLLNRLFPNNSRSKWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLAN
FAPIGGVELITLLLLFCAGSLAYAVLNRRWLMACIPLVVYATGYGLQAMQWVTPQTERTASLALIQGNIEQGLKWLPSQR
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQSDDKQYFNSVLTVGDTPHGEY
RYDLTQRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSFSQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPDTD
FLLTLSNDAWFGRSIGPLQHMEIARMRALELGKPLIRATNNGVTAVTDERGRIMAQLPQFETGVLKATVTPTRGSTPYFL
WGTTPLYLWVGLAAGFAFWRQRRAR

Sequences:

>Translated_505_residues
MNSVLSHRLMRPLAAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYLWGIGQFAVGISWVHVSIDTF
GGMPKIASLFLMTLLVGYLALYPSLFGWLLNRLFPNNSRSKWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLAN
FAPIGGVELITLLLLFCAGSLAYAVLNRRWLMACIPLVVYATGYGLQAMQWVTPQTERTASLALIQGNIEQGLKWLPSQR
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQSDDKQYFNSVLTVGDTPHGEY
RYDLTQRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSFSQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPDTD
FLLTLSNDAWFGRSIGPLQHMEIARMRALELGKPLIRATNNGVTAVTDERGRIMAQLPQFETGVLKATVTPTRGSTPYFL
WGTTPLYLWVGLAAGFAFWRQRRAR
>Mature_505_residues
MNSVLSHRLMRPLAAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYLWGIGQFAVGISWVHVSIDTF
GGMPKIASLFLMTLLVGYLALYPSLFGWLLNRLFPNNSRSKWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLAN
FAPIGGVELITLLLLFCAGSLAYAVLNRRWLMACIPLVVYATGYGLQAMQWVTPQTERTASLALIQGNIEQGLKWLPSQR
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQSDDKQYFNSVLTVGDTPHGEY
RYDLTQRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSFSQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPDTD
FLLTLSNDAWFGRSIGPLQHMEIARMRALELGKPLIRATNNGVTAVTDERGRIMAQLPQFETGVLKATVTPTRGSTPYFL
WGTTPLYLWVGLAAGFAFWRQRRAR

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=509, Percent_Identity=48.5265225933202, Blast_Score=467, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_VIBCH (Q9KTE4)

Other databases:

- EMBL:   AE003852
- PIR:   A82261
- RefSeq:   NP_230605.1
- ProteinModelPortal:   Q9KTE4
- GeneID:   2614211
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC0958
- TIGR:   VC_0958
- HOGENOM:   HBG616234
- OMA:   IAPYICY
- ProtClustDB:   PRK00302
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 56988; Mature: 56988

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2506d4a8)-; HASH(0x25a7e39c)-; HASH(0x260f1258)-; HASH(0x25dc2040)-; HASH(0x23e697a0)-; HASH(0x25f6bd40)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVLSHRLMRPLAAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGIGQFAVGISWVHVSIDTFGGMPKIASLFLMTLLVGYLALYPSLFGWLLNRLFPNNSRS
HHHHHHHHEEEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLANFAPIGGVELITLLLLFCAGS
CEEECCHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHH
LAYAVLNRRWLMACIPLVVYATGYGLQAMQWVTPQTERTASLALIQGNIEQGLKWLPSQR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHEEEEEECCHHHHHHHCCCCC
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQS
CCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
DDKQYFNSVLTVGDTPHGEYRYDLTQRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSF
CHHHHHHHHEECCCCCCCCEEEHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCHHHC
SQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPDTDFLLTLSNDAWFGRSIGPLQH
CCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHH
MEIARMRALELGKPLIRATNNGVTAVTDERGRIMAQLPQFETGVLKATVTPTRGSTPYFL
HHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCHHHHCCCCCCCEEEEEECCCCCCCCEEE
WGTTPLYLWVGLAAGFAFWRQRRAR
ECCCHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNSVLSHRLMRPLAAAFVGVITPLAFAPYQFWPLALLSPFILLLLLHQQSAKRAALIAYL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WGIGQFAVGISWVHVSIDTFGGMPKIASLFLMTLLVGYLALYPSLFGWLLNRLFPNNSRS
HHHHHHHHEEEEEEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KWLCAAPALWLITDWLRGWVMTGFPWLWLGYSQIDSPLANFAPIGGVELITLLLLFCAGS
CEEECCHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHH
LAYAVLNRRWLMACIPLVVYATGYGLQAMQWVTPQTERTASLALIQGNIEQGLKWLPSQR
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHEEEEEECCHHHHHHHCCCCC
WPTIMKYTDLTRENWDADVIIWPEAAIPAFEYEISSFLHNLDAAARMNQSAVITGIINQS
CCCHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
DDKQYFNSVLTVGDTPHGEYRYDLTQRYHKYHLLPFGEFVPFEEILRPLAPFFNLPMSSF
CHHHHHHHHEECCCCCCCCEEEHHHHHHHHEECCCCCCCCCHHHHHHHHHHHHCCCHHHC
SQGAYVQPNLIAKGFAFVTALCYEIIFNEQVRDNVTPDTDFLLTLSNDAWFGRSIGPLQH
CCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCEEEEECCCCCCCCCCCCHHH
MEIARMRALELGKPLIRATNNGVTAVTDERGRIMAQLPQFETGVLKATVTPTRGSTPYFL
HHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCHHHHCCCCCCCEEEEEECCCCCCCCEEE
WGTTPLYLWVGLAAGFAFWRQRRAR
ECCCHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301