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The map label for this gene is treB [H]

Identifier: 227081085

GI number: 227081085

Start: 927203

End: 928639

Strand: Direct

Name: treB [H]

Synonym: VCM66_0867

Alternate gene names: 227081085

Gene position: 927203-928639 (Clockwise)

Preceding gene: 227081084

Following gene: 227081086

Centisome position: 32.06

GC content: 49.97

Gene sequence:

>1437_bases
GTGGACGAGGATATGAGCAAGATAGCGAAACAAGACGTGACGCGTCTTATCGAATTGGTGGGAGGCGAAAGCAATATTGC
GAGCGTTACTCACTGTTTGACACGCTTACGCTTTGTGCTGAATCAGCCAGAGCAGGCTGACAAGGCGGGTTTGGAAGCGC
TGAGCATGGTAAAGGGCTGCTTTACCAATGCGGGGCAATTTCAGGTAGTCATTGGCACTGAAGTTGATCAAGTGTACAAA
ATGCTGCTGGAACAAACCGGGAAACAAGCCGTTTCCAAAGACGATGCCAAAGTCGCAGCGCGTCAAAACATGAATGTGCT
AGAGCGTGGTATTTCCCATTTGGCTGAAATTTTTGTGCCACTGCTGCCTGCGATCATCACCGGTGGTTTGATCCTCGGTT
TTCGTAATGTGATAGGTGACATTCGCATGTTTGATGGCAAAACGCTGACTGAAATCAGTCAGTTTTGGGCATCGGTTCAT
GCGTTCTTGTGGCTGATTGGCGAAGCGATTTTCTTCTTCTTACCTGTCGGTGTCTGCTGGTCAACCGTGAAAAAACTTGG
CGGTACCCCAATCCTCGGTATTACCCTTGGGGTAACACTGGTTTCTCCGCAATTGATGAACGCTTACCTGATCGGTAAAG
AAGTGCCAGAAGTATGGGATTTCGGGCTGTTTGCGATTGAAAAAGTGGGTTACCAAGCTCAGGTTATCCCCGCTATCTTG
GCTGGTGTGGCATTAGCCTTTATTGAAAATAATTTAAGACGTGTGGTGCCTTCTTACCTCTATCTGGTAGTGGTGCCGTT
TGTATCAATCATTGTGTCAGTGGTGCTTGCTCACGCCTTCATCGGCCCATTTGGTCGCGTGATTGGTGATGGTGTGGCAT
TTGCAGCGAAAGCGGCAATGACGGGTGATTTCGCGGTGATTGGTTCGACGCTGTTTGGCTTCATGTATGCTCCTCTCGTG
ATTACCGGCATTCACCACACCACTAACGCGGTGGATCTGCAGCTGATGCAAGAGCTTGGTGGTACGCCGATTTGGCCATT
GATCGCGCTATCTAACATTGCGCAAGCATCGGCAGTAGTGGGCATCATTATCATCAGTAAAAAGCAGGGCGAACGGGACA
TTTCTGTACCGGCGGCGATTTCCGCTTACCTTGGTGTAACTGAACCTGCGATGTACGGTATCAACCTTAAATACAAATTC
CCTATGCTGAGCGCAATGATCGGCAGTGCTTTGGCTGCCGCAGTCTGTGGTAGCGCAGGTGTAATGGCCAATGGTATCGG
TGTCGGCGGCTTGCCGGGTATTCTCTCGATTCAGCCGCAGTTTTGGAGTATTTACCTCGTCGCCATGCTAATTGCGATTT
TGGTACCCGCAGCATTGACTCTGCTGATGTACAAGCGCGCACAGAGTTCAGGCAAACTGGCCGTTTCGGCTGCCTAA

Upstream 100 bases:

>100_bases
ATGGGATTGTTCCCATTTTTATCTGTTATGCATTGTGTCAATATCGCACCAATTGATTTGGGACTGTTCCCAATTGCTGC
AATGATAATAATTCAATAGG

Downstream 100 bases:

>100_bases
TCTCTACCCGATTGAGGAGTGGTTTACGCCACTCCTTTCTCTGTTTTTGAGTCAATTTTTTTGAGTAAGTGAGAGTAGTA
TGAGTAGCTCAACCCAATCC

Product: PTS system trehalose(maltose)-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MDEDMSKIAKQDVTRLIELVGGESNIASVTHCLTRLRFVLNQPEQADKAGLEALSMVKGCFTNAGQFQVVIGTEVDQVYK
MLLEQTGKQAVSKDDAKVAARQNMNVLERGISHLAEIFVPLLPAIITGGLILGFRNVIGDIRMFDGKTLTEISQFWASVH
AFLWLIGEAIFFFLPVGVCWSTVKKLGGTPILGITLGVTLVSPQLMNAYLIGKEVPEVWDFGLFAIEKVGYQAQVIPAIL
AGVALAFIENNLRRVVPSYLYLVVVPFVSIIVSVVLAHAFIGPFGRVIGDGVAFAAKAAMTGDFAVIGSTLFGFMYAPLV
ITGIHHTTNAVDLQLMQELGGTPIWPLIALSNIAQASAVVGIIIISKKQGERDISVPAAISAYLGVTEPAMYGINLKYKF
PMLSAMIGSALAAAVCGSAGVMANGIGVGGLPGILSIQPQFWSIYLVAMLIAILVPAALTLLMYKRAQSSGKLAVSAA

Sequences:

>Translated_478_residues
MDEDMSKIAKQDVTRLIELVGGESNIASVTHCLTRLRFVLNQPEQADKAGLEALSMVKGCFTNAGQFQVVIGTEVDQVYK
MLLEQTGKQAVSKDDAKVAARQNMNVLERGISHLAEIFVPLLPAIITGGLILGFRNVIGDIRMFDGKTLTEISQFWASVH
AFLWLIGEAIFFFLPVGVCWSTVKKLGGTPILGITLGVTLVSPQLMNAYLIGKEVPEVWDFGLFAIEKVGYQAQVIPAIL
AGVALAFIENNLRRVVPSYLYLVVVPFVSIIVSVVLAHAFIGPFGRVIGDGVAFAAKAAMTGDFAVIGSTLFGFMYAPLV
ITGIHHTTNAVDLQLMQELGGTPIWPLIALSNIAQASAVVGIIIISKKQGERDISVPAAISAYLGVTEPAMYGINLKYKF
PMLSAMIGSALAAAVCGSAGVMANGIGVGGLPGILSIQPQFWSIYLVAMLIAILVPAALTLLMYKRAQSSGKLAVSAA
>Mature_478_residues
MDEDMSKIAKQDVTRLIELVGGESNIASVTHCLTRLRFVLNQPEQADKAGLEALSMVKGCFTNAGQFQVVIGTEVDQVYK
MLLEQTGKQAVSKDDAKVAARQNMNVLERGISHLAEIFVPLLPAIITGGLILGFRNVIGDIRMFDGKTLTEISQFWASVH
AFLWLIGEAIFFFLPVGVCWSTVKKLGGTPILGITLGVTLVSPQLMNAYLIGKEVPEVWDFGLFAIEKVGYQAQVIPAIL
AGVALAFIENNLRRVVPSYLYLVVVPFVSIIVSVVLAHAFIGPFGRVIGDGVAFAAKAAMTGDFAVIGSTLFGFMYAPLV
ITGIHHTTNAVDLQLMQELGGTPIWPLIALSNIAQASAVVGIIIISKKQGERDISVPAAISAYLGVTEPAMYGINLKYKF
PMLSAMIGSALAAAVCGSAGVMANGIGVGGLPGILSIQPQFWSIYLVAMLIAILVPAALTLLMYKRAQSSGKLAVSAA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=471, Percent_Identity=68.1528662420382, Blast_Score=650, Evalue=0.0,
Organism=Escherichia coli, GI1790159, Length=438, Percent_Identity=26.4840182648402, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI48994906, Length=441, Percent_Identity=27.2108843537415, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788769, Length=417, Percent_Identity=24.7002398081535, Blast_Score=109, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 50854; Mature: 50854

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEDMSKIAKQDVTRLIELVGGESNIASVTHCLTRLRFVLNQPEQADKAGLEALSMVKGC
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FTNAGQFQVVIGTEVDQVYKMLLEQTGKQAVSKDDAKVAARQNMNVLERGISHLAEIFVP
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
LLPAIITGGLILGFRNVIGDIRMFDGKTLTEISQFWASVHAFLWLIGEAIFFFLPVGVCW
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STVKKLGGTPILGITLGVTLVSPQLMNAYLIGKEVPEVWDFGLFAIEKVGYQAQVIPAIL
HHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
AGVALAFIENNLRRVVPSYLYLVVVPFVSIIVSVVLAHAFIGPFGRVIGDGVAFAAKAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TGDFAVIGSTLFGFMYAPLVITGIHHTTNAVDLQLMQELGGTPIWPLIALSNIAQASAVV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
GIIIISKKQGERDISVPAAISAYLGVTEPAMYGINLKYKFPMLSAMIGSALAAAVCGSAG
EEEEEECCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHHHHHHHCCCC
VMANGIGVGGLPGILSIQPQFWSIYLVAMLIAILVPAALTLLMYKRAQSSGKLAVSAA
CCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MDEDMSKIAKQDVTRLIELVGGESNIASVTHCLTRLRFVLNQPEQADKAGLEALSMVKGC
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FTNAGQFQVVIGTEVDQVYKMLLEQTGKQAVSKDDAKVAARQNMNVLERGISHLAEIFVP
HCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHH
LLPAIITGGLILGFRNVIGDIRMFDGKTLTEISQFWASVHAFLWLIGEAIFFFLPVGVCW
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STVKKLGGTPILGITLGVTLVSPQLMNAYLIGKEVPEVWDFGLFAIEKVGYQAQVIPAIL
HHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHH
AGVALAFIENNLRRVVPSYLYLVVVPFVSIIVSVVLAHAFIGPFGRVIGDGVAFAAKAAM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
TGDFAVIGSTLFGFMYAPLVITGIHHTTNAVDLQLMQELGGTPIWPLIALSNIAQASAVV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHE
GIIIISKKQGERDISVPAAISAYLGVTEPAMYGINLKYKFPMLSAMIGSALAAAVCGSAG
EEEEEECCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEECHHHHHHHHHHHHHHHHCCCC
VMANGIGVGGLPGILSIQPQFWSIYLVAMLIAILVPAALTLLMYKRAQSSGKLAVSAA
CCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]