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The map label for this gene is metI

Identifier: 227081081

GI number: 227081081

Start: 923454

End: 924131

Strand: Reverse

Name: metI

Synonym: VCM66_0863

Alternate gene names: 227081081

Gene position: 924131-923454 (Counterclockwise)

Preceding gene: 227081082

Following gene: 227081080

Centisome position: 31.95

GC content: 53.39

Gene sequence:

>678_bases
ATGTCCTTTAATACGATTGCACAATGGTTTGCACTCAATAGCGACCTACTGTTAACCGCCACATGGCAAACACTGTATAT
GGTCGCGATTGCCGGTGCGGTGGGTTTTGCGCTCGGGATTCCGCTAGGTGTGATTCTCCATACCACCAAAAAAGAGGGCT
TACTGGAAAACCTACCGCTGAACCGTGCGCTCGGCGCCGTGGTTAACATCGGTCGCTCGGTGCCCTTTTTGGTGTTGATG
GTCGCCATCATTCCTGTCACCAAACTGATTGTCGGCACTTTTATCGGTACCACTGCGGCCATTGTGCCACTCACGATTGG
GGCGATTCCGTTTGTAGCGCGCCTGATTGAGAGTGCGCTGCTTGAAGTGCCAACCGGCTTAGTGGAAGCGGCGCAATCTA
TGGGTGCGACGCCACTGCAAATCATTCGTAAGGTACTGCTCCCTGAAGCGCTGCCGACGATTTTAAACTCAGTCACGATT
ACTCTCGTGACACTGGTCAGCTACTCAGCCATGGCAGGTACCGTTGGCGGTGGTGGTCTGGGCGATGTGGCGATCCGCTA
TGGATTCCACCGTTACGACATCACCATCATGGCGGTCACTGTGGTCATGCTGATTGTGCTGGTACAAATTATTCAATCCA
TCGGCGATGCGTTGGTACGCCGCGTCGATCATCGATAA

Upstream 100 bases:

>100_bases
TTTGGCATGATGGTCGCTGAAATTTTTGGTAATGCCGACGATGATGAAGCCGCGATTCGTTATCTGCGCGAAAACAACGT
AAAAGTAGAGGTGCTGGGTT

Downstream 100 bases:

>100_bases
GCAAAACAAAAGCCTTTTTTGAACAAGGAGTTCATCATGAAGTTTAGCCTGAAAAGTTTACTGACTATCGCTGCTGCAGC
CTCAACCCTAATTTTGGCCG

Product: ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSFNTIAQWFALNSDLLLTATWQTLYMVAIAGAVGFALGIPLGVILHTTKKEGLLENLPLNRALGAVVNIGRSVPFLVLM
VAIIPVTKLIVGTFIGTTAAIVPLTIGAIPFVARLIESALLEVPTGLVEAAQSMGATPLQIIRKVLLPEALPTILNSVTI
TLVTLVSYSAMAGTVGGGGLGDVAIRYGFHRYDITIMAVTVVMLIVLVQIIQSIGDALVRRVDHR

Sequences:

>Translated_225_residues
MSFNTIAQWFALNSDLLLTATWQTLYMVAIAGAVGFALGIPLGVILHTTKKEGLLENLPLNRALGAVVNIGRSVPFLVLM
VAIIPVTKLIVGTFIGTTAAIVPLTIGAIPFVARLIESALLEVPTGLVEAAQSMGATPLQIIRKVLLPEALPTILNSVTI
TLVTLVSYSAMAGTVGGGGLGDVAIRYGFHRYDITIMAVTVVMLIVLVQIIQSIGDALVRRVDHR
>Mature_224_residues
SFNTIAQWFALNSDLLLTATWQTLYMVAIAGAVGFALGIPLGVILHTTKKEGLLENLPLNRALGAVVNIGRSVPFLVLMV
AIIPVTKLIVGTFIGTTAAIVPLTIGAIPFVARLIESALLEVPTGLVEAAQSMGATPLQIIRKVLLPEALPTILNSVTIT
LVTLVSYSAMAGTVGGGGLGDVAIRYGFHRYDITIMAVTVVMLIVLVQIIQSIGDALVRRVDHR

Specific function: Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1786397, Length=210, Percent_Identity=53.8095238095238, Blast_Score=198, Evalue=2e-52,
Organism=Escherichia coli, GI1789033, Length=192, Percent_Identity=31.25, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METI_VIBCH (Q9KTJ6)

Other databases:

- EMBL:   AE003852
- PIR:   B82266
- RefSeq:   NP_230553.1
- ProteinModelPortal:   Q9KTJ6
- SMR:   Q9KTJ6
- GeneID:   2614197
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC0906
- TIGR:   VC_0906
- HOGENOM:   HBG592565
- OMA:   FITWIST
- ProtClustDB:   CLSK874148
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 23763; Mature: 23632

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x24f81050)-; HASH(0x25631038)-; HASH(0x25f6f660)-; HASH(0x25fb4994)-; HASH(0x2541d040)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFNTIAQWFALNSDLLLTATWQTLYMVAIAGAVGFALGIPLGVILHTTKKEGLLENLPL
CCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCH
NRALGAVVNIGRSVPFLVLMVAIIPVTKLIVGTFIGTTAAIVPLTIGAIPFVARLIESAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVPTGLVEAAQSMGATPLQIIRKVLLPEALPTILNSVTITLVTLVSYSAMAGTVGGGGL
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GDVAIRYGFHRYDITIMAVTVVMLIVLVQIIQSIGDALVRRVDHR
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
SFNTIAQWFALNSDLLLTATWQTLYMVAIAGAVGFALGIPLGVILHTTKKEGLLENLPL
CHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCH
NRALGAVVNIGRSVPFLVLMVAIIPVTKLIVGTFIGTTAAIVPLTIGAIPFVARLIESAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEVPTGLVEAAQSMGATPLQIIRKVLLPEALPTILNSVTITLVTLVSYSAMAGTVGGGGL
HHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GDVAIRYGFHRYDITIMAVTVVMLIVLVQIIQSIGDALVRRVDHR
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301