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The map label for this gene is xni [H]

Identifier: 227081073

GI number: 227081073

Start: 913787

End: 914638

Strand: Reverse

Name: xni [H]

Synonym: VCM66_0855

Alternate gene names: 227081073

Gene position: 914638-913787 (Counterclockwise)

Preceding gene: 227081074

Following gene: 227081067

Centisome position: 31.62

GC content: 48.36

Gene sequence:

>852_bases
TTGGGTAGTAATCTTGACGGATTTGATTACAATAAGGGCCTCACAAGCCCTTATTTTTTATGGTTTTTGGTTATGTCTCT
TCATCTTGTCATTATTGATGCGCTTAATTTGATCCGCCGCGTTCACTCCGCGCAGCCCGATCCCAACGACATCACCAGAA
CCGCGGAAACCACAACACGCACTCTGCAGCGCATCATTAATGAAGCGCAGCCCAGCCATATGATCGCGGTGTTTGATCAT
CATTTATCTGATCGTGGCTGGCGCGCTGAGTTACTCCCAACTTACAAAGCCAATCGCAAACCCATGCCAGACGTTTTGCA
GCAAGGGCTAGATTCCATTCAAGATGCGTGGTGGCAACTGGGGATTGATTCGCTGTTATCGGAAGGCGATGAAGCGGACG
ATCTGGTTGCAACACTGGCTTGTAAAGTGGCGGCTCATCAAGAAAAAGTGACAATTATCTCGACCGATAAGGGCTACTGT
CAGTTACTTTCTCCAACCTTACAAATCCGCGACTACTTTCAGCAACGTTGGTTAGATGAGCCTTTTATCGCTCAGGAGTT
TGGCGTTACTCCCGCACAATTAACCGACTATTGGGGATTAACGGGCGTCAGCTCAAGCCAAATTCCCGGCGTGGCCGGTA
TTGGCCCGAAAGCGGCGAAAGAGATTTTAAACCAGTTCTCGAGCATTGAAGAGGCGTATGCCAGCCCTGAACTACCGGCA
AAGTATCGCAAAAAACTCGATCCTCACATTGAAATGGCGCGCATCTGTAAACAAGTCAGTGCCTTGAAAACGGACATCGA
GCTTGGGTTTAACTTGCAAGATATCCGTTTTAACTCATCGTCCGCGGACTAA

Upstream 100 bases:

>100_bases
AAAACCGGATGAAACTTCCAGGCGGCAGCGCATACGAGCCTTGCTATAAGATAGTGACTTAAACCTAAAGCCAATGTCTG
CTCAAGCCTGAATTCGTCGC

Downstream 100 bases:

>100_bases
ATCCCCTCTGATTAGGCATCACAACACAGACTACTGACTTTTCCACGCCGCGTAACTAAACCAGATCCAGCCTAAGATGA
ACATCACGCCACCAAAAGGC

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MGSNLDGFDYNKGLTSPYFLWFLVMSLHLVIIDALNLIRRVHSAQPDPNDITRTAETTTRTLQRIINEAQPSHMIAVFDH
HLSDRGWRAELLPTYKANRKPMPDVLQQGLDSIQDAWWQLGIDSLLSEGDEADDLVATLACKVAAHQEKVTIISTDKGYC
QLLSPTLQIRDYFQQRWLDEPFIAQEFGVTPAQLTDYWGLTGVSSSQIPGVAGIGPKAAKEILNQFSSIEEAYASPELPA
KYRKKLDPHIEMARICKQVSALKTDIELGFNLQDIRFNSSSAD

Sequences:

>Translated_283_residues
MGSNLDGFDYNKGLTSPYFLWFLVMSLHLVIIDALNLIRRVHSAQPDPNDITRTAETTTRTLQRIINEAQPSHMIAVFDH
HLSDRGWRAELLPTYKANRKPMPDVLQQGLDSIQDAWWQLGIDSLLSEGDEADDLVATLACKVAAHQEKVTIISTDKGYC
QLLSPTLQIRDYFQQRWLDEPFIAQEFGVTPAQLTDYWGLTGVSSSQIPGVAGIGPKAAKEILNQFSSIEEAYASPELPA
KYRKKLDPHIEMARICKQVSALKTDIELGFNLQDIRFNSSSAD
>Mature_282_residues
GSNLDGFDYNKGLTSPYFLWFLVMSLHLVIIDALNLIRRVHSAQPDPNDITRTAETTTRTLQRIINEAQPSHMIAVFDHH
LSDRGWRAELLPTYKANRKPMPDVLQQGLDSIQDAWWQLGIDSLLSEGDEADDLVATLACKVAAHQEKVTIISTDKGYCQ
LLSPTLQIRDYFQQRWLDEPFIAQEFGVTPAQLTDYWGLTGVSSSQIPGVAGIGPKAAKEILNQFSSIEEAYASPELPAK
YRKKLDPHIEMARICKQVSALKTDIELGFNLQDIRFNSSSAD

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing [H]

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain [H]

Homologues:

Organism=Escherichia coli, GI226510970, Length=254, Percent_Identity=51.9685039370079, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1790294, Length=267, Percent_Identity=28.4644194756554, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR022895 [H]

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 31746; Mature: 31615

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure 
GSNLDGFDYNKGLTSPYFLWFLVMSLHLVIIDALNLIRRVHSAQPDPNDITRTAETTTR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
TLQRIINEAQPSHMIAVFDHHLSDRGWRAELLPTYKANRKPMPDVLQQGLDSIQDAWWQL
HHHHHHHHCCCCCEEHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GIDSLLSEGDEADDLVATLACKVAAHQEKVTIISTDKGYCQLLSPTLQIRDYFQQRWLDE
CHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCC
PFIAQEFGVTPAQLTDYWGLTGVSSSQIPGVAGIGPKAAKEILNQFSSIEEAYASPELPA
CHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
KYRKKLDPHIEMARICKQVSALKTDIELGFNLQDIRFNSSSAD
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]