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The map label for this gene is acfB [H]

Identifier: 227081017

GI number: 227081017

Start: 858946

End: 860826

Strand: Direct

Name: acfB [H]

Synonym: VCM66_0797

Alternate gene names: 227081017

Gene position: 858946-860826 (Clockwise)

Preceding gene: 227081016

Following gene: 227081018

Centisome position: 29.7

GC content: 34.24

Gene sequence:

>1881_bases
ATGAAGTTTTCTATCAAGTTACTAATGATTTTTACATCAATTATAATTACTATTTCATCTATCCTTACTTACTTTCAGAT
GCATGGAACCAATGAATATCTTGATCGTACGATAAAAGATACTATTTCTGAAACGCTAGACTCTTTGGAAGATAAAATAA
ATCTTTCTATTGAGTCCAAGGTCGATGTGTCAAAATCTGTTATCGACATTTATGAAAATTTACTGGAGGGGGAATCCCCT
CTCAGTAAATTTAAGGATGTTGATGTCAATCATCTTTCAAATGTTTTTCAATTGTTCGGATATGCTGATGAAAGAACAGG
AGAGATCATTACTAATGACCCAAACTTTAAAGTGCCTACAGGATTCGATCCAAGGACTCGATCGTGGTATTTAAATGCAA
AAAAATTGAATACCTTTAGTTTGTCTGAGCCGTATGTCGATCTCATTACAGAGAAGTTAATGGTGACAACAAGTGCACCA
ATATATAATAAAAACGATTTAACAGGAGTTATATTTTTTGATATACCACTAGATGACGTTCAGGAATTAATTAAAAGCTA
CAATCCATTTGATGCCGGCACGATTTTTATCGTTGATAACAGTGGGAAAATAATTTTCGGTAATAAAAATGATATATCGG
GTAAAAATTTATTTGGAGACTTTGATAGCTTCCCTCTATCGGTAAGTGAGTCAAAAACGAAAGATAAAAATGGGGTAAAT
TACGATGTATTCATCAAAATGTCAGACTTTGGCGGTTGGAATCTTGTTTCTATTATCGACCATGATAAAGCACGCTCTGA
TATTATCACGTTGAGAAACAATAGTATATTTACTGCCGTCATTTTAGCAAGTGTTTTCTTTGCTATCTTGTTGTTTACTA
TGCGGTTAATGCTGAAGCCATTGCATCAATTAACCGATGCAATGGTAAATATTTCATCGGGCAGTGCTGATCTTACGGTT
CGTATCCCGAATAGTACGGATCAAGAGTTTTCAAAAATAATAAATTCCTTTAACATTTTTGTTGGTAATCTGCAATCTAT
TGTGTCGGAGGTTAAAATGAACTCAGAAAAAATAAATTGCATAACTACTGAAACACAAGAGCTAGTCGAAGTTTGCAATA
ATAGCGTAGCTGATCAGTATCGTGAACTTGATATGCTAGCTAGCTCAATGAATGAGATGGTGGCAACATCTAATCAGATT
GCACAAATTACATCCGAAGCATCAGAGATCACATCTAAGATTAACGGTCAAGTGAATGAAGGAGTCGGTGCTGTTTCTTC
TGTTACCGAAAGTGTAGGTAATTTAGTTGAGAAGTTGGATAAGACGAAATCTGTTATCCAAGATCTTAATCGCCAAACTC
AAAATATAGATGTTATTTTGAAGGCTATTAATGATATTGCTGACCAAACAAACCTTCTTGCTCTTAATGCTGCAATTGAG
GCTGCACGAGCTGGGGAAAATGGACGAGGTTTTGCTGTGGTTGCTGATGAGGTACGCAGCCTAGCAATAAAGACACAAGA
GTCTACTAAAAATATAGGAAGTATTATCCATATATTACAAGAAAACTCTTTGCTATCCGTTCATGTTATGGATGAAAGTT
TTAATATTGCCTCTGAAACTATGACTATATCAGCTGATTCAAAACAATGTTTAGACAATATTAGTCAATCAGTAATACAA
ATTGTTGATATCACAAATCAAGTAGCTACAGCTGCTTACGAACAAAGTCACGTATCAGAGGAAATAAACAGCAACTCTAT
TTCTATAAAAGATAAAGCAGATACCTTATCAAGTTTGGGTAATAAGATTTCTCAACAGGCTTATTCTCAAAAAGCACTGA
TTGGTCATCAAGATGATTTAATCAGTAAGTTTATCATTTAA

Upstream 100 bases:

>100_bases
TAGAGTCTCATGTCGGTATTGCTTATATATCCCTCTTGGACCAAGCATTATTATCTCTTTTGTAATTGTTTTTTTTTCAA
TCCGTTTAATGTGAGCTAAA

Downstream 100 bases:

>100_bases
TATGGATGTATTTCATGAAAAGTAAGAATCGATTTTTATTAATTTCTTTACTATCATTTTCTACGAGTGTTTTTGCGGAT
GTTAATCTTTATGGACCTGG

Product: accessory colonization factor AcfB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MKFSIKLLMIFTSIIITISSILTYFQMHGTNEYLDRTIKDTISETLDSLEDKINLSIESKVDVSKSVIDIYENLLEGESP
LSKFKDVDVNHLSNVFQLFGYADERTGEIITNDPNFKVPTGFDPRTRSWYLNAKKLNTFSLSEPYVDLITEKLMVTTSAP
IYNKNDLTGVIFFDIPLDDVQELIKSYNPFDAGTIFIVDNSGKIIFGNKNDISGKNLFGDFDSFPLSVSESKTKDKNGVN
YDVFIKMSDFGGWNLVSIIDHDKARSDIITLRNNSIFTAVILASVFFAILLFTMRLMLKPLHQLTDAMVNISSGSADLTV
RIPNSTDQEFSKIINSFNIFVGNLQSIVSEVKMNSEKINCITTETQELVEVCNNSVADQYRELDMLASSMNEMVATSNQI
AQITSEASEITSKINGQVNEGVGAVSSVTESVGNLVEKLDKTKSVIQDLNRQTQNIDVILKAINDIADQTNLLALNAAIE
AARAGENGRGFAVVADEVRSLAIKTQESTKNIGSIIHILQENSLLSVHVMDESFNIASETMTISADSKQCLDNISQSVIQ
IVDITNQVATAAYEQSHVSEEINSNSISIKDKADTLSSLGNKISQQAYSQKALIGHQDDLISKFII

Sequences:

>Translated_626_residues
MKFSIKLLMIFTSIIITISSILTYFQMHGTNEYLDRTIKDTISETLDSLEDKINLSIESKVDVSKSVIDIYENLLEGESP
LSKFKDVDVNHLSNVFQLFGYADERTGEIITNDPNFKVPTGFDPRTRSWYLNAKKLNTFSLSEPYVDLITEKLMVTTSAP
IYNKNDLTGVIFFDIPLDDVQELIKSYNPFDAGTIFIVDNSGKIIFGNKNDISGKNLFGDFDSFPLSVSESKTKDKNGVN
YDVFIKMSDFGGWNLVSIIDHDKARSDIITLRNNSIFTAVILASVFFAILLFTMRLMLKPLHQLTDAMVNISSGSADLTV
RIPNSTDQEFSKIINSFNIFVGNLQSIVSEVKMNSEKINCITTETQELVEVCNNSVADQYRELDMLASSMNEMVATSNQI
AQITSEASEITSKINGQVNEGVGAVSSVTESVGNLVEKLDKTKSVIQDLNRQTQNIDVILKAINDIADQTNLLALNAAIE
AARAGENGRGFAVVADEVRSLAIKTQESTKNIGSIIHILQENSLLSVHVMDESFNIASETMTISADSKQCLDNISQSVIQ
IVDITNQVATAAYEQSHVSEEINSNSISIKDKADTLSSLGNKISQQAYSQKALIGHQDDLISKFII
>Mature_626_residues
MKFSIKLLMIFTSIIITISSILTYFQMHGTNEYLDRTIKDTISETLDSLEDKINLSIESKVDVSKSVIDIYENLLEGESP
LSKFKDVDVNHLSNVFQLFGYADERTGEIITNDPNFKVPTGFDPRTRSWYLNAKKLNTFSLSEPYVDLITEKLMVTTSAP
IYNKNDLTGVIFFDIPLDDVQELIKSYNPFDAGTIFIVDNSGKIIFGNKNDISGKNLFGDFDSFPLSVSESKTKDKNGVN
YDVFIKMSDFGGWNLVSIIDHDKARSDIITLRNNSIFTAVILASVFFAILLFTMRLMLKPLHQLTDAMVNISSGSADLTV
RIPNSTDQEFSKIINSFNIFVGNLQSIVSEVKMNSEKINCITTETQELVEVCNNSVADQYRELDMLASSMNEMVATSNQI
AQITSEASEITSKINGQVNEGVGAVSSVTESVGNLVEKLDKTKSVIQDLNRQTQNIDVILKAINDIADQTNLLALNAAIE
AARAGENGRGFAVVADEVRSLAIKTQESTKNIGSIIHILQENSLLSVHVMDESFNIASETMTISADSKQCLDNISQSVIQ
IVDITNQVATAAYEQSHVSEEINSNSISIKDKADTLSSLGNKISQQAYSQKALIGHQDDLISKFII

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=302, Percent_Identity=30.4635761589404, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788194, Length=476, Percent_Identity=26.6806722689076, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788195, Length=283, Percent_Identity=31.4487632508834, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1787690, Length=335, Percent_Identity=28.3582089552239, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1789453, Length=233, Percent_Identity=33.4763948497854, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 69202; Mature: 69202

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSIKLLMIFTSIIITISSILTYFQMHGTNEYLDRTIKDTISETLDSLEDKINLSIESK
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
VDVSKSVIDIYENLLEGESPLSKFKDVDVNHLSNVFQLFGYADERTGEIITNDPNFKVPT
CCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCC
GFDPRTRSWYLNAKKLNTFSLSEPYVDLITEKLMVTTSAPIYNKNDLTGVIFFDIPLDDV
CCCCCCCEEEEEEEECCEECCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCHHHH
QELIKSYNPFDAGTIFIVDNSGKIIFGNKNDISGKNLFGDFDSFPLSVSESKTKDKNGVN
HHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YDVFIKMSDFGGWNLVSIIDHDKARSDIITLRNNSIFTAVILASVFFAILLFTMRLMLKP
EEEEEEEECCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LHQLTDAMVNISSGSADLTVRIPNSTDQEFSKIINSFNIFVGNLQSIVSEVKMNSEKINC
HHHHHHHHEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ITTETQELVEVCNNSVADQYRELDMLASSMNEMVATSNQIAQITSEASEITSKINGQVNE
EECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHC
GVGAVSSVTESVGNLVEKLDKTKSVIQDLNRQTQNIDVILKAINDIADQTNLLALNAAIE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
AARAGENGRGFAVVADEVRSLAIKTQESTKNIGSIIHILQENSLLSVHVMDESFNIASET
HHHCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCE
MTISADSKQCLDNISQSVIQIVDITNQVATAAYEQSHVSEEINSNSISIKDKADTLSSLG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHH
NKISQQAYSQKALIGHQDDLISKFII
HHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MKFSIKLLMIFTSIIITISSILTYFQMHGTNEYLDRTIKDTISETLDSLEDKINLSIESK
CCEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
VDVSKSVIDIYENLLEGESPLSKFKDVDVNHLSNVFQLFGYADERTGEIITNDPNFKVPT
CCHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCC
GFDPRTRSWYLNAKKLNTFSLSEPYVDLITEKLMVTTSAPIYNKNDLTGVIFFDIPLDDV
CCCCCCCEEEEEEEECCEECCCCCHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCHHHH
QELIKSYNPFDAGTIFIVDNSGKIIFGNKNDISGKNLFGDFDSFPLSVSESKTKDKNGVN
HHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YDVFIKMSDFGGWNLVSIIDHDKARSDIITLRNNSIFTAVILASVFFAILLFTMRLMLKP
EEEEEEEECCCCCEEEEEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LHQLTDAMVNISSGSADLTVRIPNSTDQEFSKIINSFNIFVGNLQSIVSEVKMNSEKINC
HHHHHHHHEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
ITTETQELVEVCNNSVADQYRELDMLASSMNEMVATSNQIAQITSEASEITSKINGQVNE
EECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHC
GVGAVSSVTESVGNLVEKLDKTKSVIQDLNRQTQNIDVILKAINDIADQTNLLALNAAIE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHH
AARAGENGRGFAVVADEVRSLAIKTQESTKNIGSIIHILQENSLLSVHVMDESFNIASET
HHHCCCCCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCE
MTISADSKQCLDNISQSVIQIVDITNQVATAAYEQSHVSEEINSNSISIKDKADTLSSLG
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHH
NKISQQAYSQKALIGHQDDLISKFII
HHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353924; 9384377 [H]