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The map label for this gene is tcpS

Identifier: 227081011

GI number: 227081011

Start: 853159

End: 853617

Strand: Direct

Name: tcpS

Synonym: VCM66_0791

Alternate gene names: 227081011

Gene position: 853159-853617 (Clockwise)

Preceding gene: 227081010

Following gene: 227081012

Centisome position: 29.5

GC content: 31.15

Gene sequence:

>459_bases
ATGAATATCAAACTATCATTTATTTCAATTGCTTTTCTATCGTTAAGTTTTAATGTTGCTGCTAACGAATTTGAAAAATC
TCAAGAGCACTACAAAAGTGTAACTGATTTAAAAAACAAAATCGAAATACTAGAGTTAGAAAAGAAAATAACAGAGCTGA
GTGGCGAGATTCGCAATGCAAGAATGCCAAAAATAGATAAGTCTGCACCCGTTTTATCTCCTCAGCCTGTAGTAAAATCG
TCAGAAGAATTACAAAAAAGTATCGAACATATAGAAGAAGAGCTCAAAGTGGAATTGGCTTATTTGGTTAACAATGGTCA
ACAAAAAAAATATACATTCAATCTTAATGGCAAACTTATCACATTGGTTAATGGTGATTTTGTAAATGGTTGGAAATTCA
TTGAAGACCAAAATAAAATTCAATTTTCCAAGGGCAATAAGGTAATCGATGTCAATTGA

Upstream 100 bases:

>100_bases
TATTATGAATAATAGTATGATGATTACGTCTATCTCTTTGCAAAATTCAAGTTTTAAATCCAAGTTAAATTATTACTGCT
ATTAAGGTGGGATTAGAGAA

Downstream 100 bases:

>100_bases
TATAAAGTATTTAAGTCGTATTGATATAGATCGTGAGGAGTTTTTCTTTAAAGACTCGAGATTAATGTGTAAGAAATTCG
ATGAAGAGCGTGAGGTATTA

Product: toxin co-regulated pilus biosynthesis protein S

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpS

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNARMPKIDKSAPVLSPQPVVKS
SEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLITLVNGDFVNGWKFIEDQNKIQFSKGNKVIDVN

Sequences:

>Translated_152_residues
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNARMPKIDKSAPVLSPQPVVKS
SEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLITLVNGDFVNGWKFIEDQNKIQFSKGNKVIDVN
>Mature_152_residues
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNARMPKIDKSAPVLSPQPVVKS
SEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLITLVNGDFVNGWKFIEDQNKIQFSKGNKVIDVN

Specific function: The toxin coregulated pilus (TCP) is essential for successful colonization of the small intestine

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm. Secreted

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TCPS_VIBCH (P29484)

Other databases:

- EMBL:   X64098
- EMBL:   AE003852
- PIR:   E82275
- RefSeq:   NP_230482.1
- GeneID:   2614501
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC0834
- TIGR:   VC_0834
- HOGENOM:   HBG739732
- OMA:   ILIFCAS
- ProtClustDB:   CLSK793811
- InterPro:   IPR020213
- ProDom:   PD091271

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17357; Mature: 17357

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNA
CCEEEHHHHHEEHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RMPKIDKSAPVLSPQPVVKSSEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHEEEECCCCCCEEEEECCCEEE
TLVNGDFVNGWKFIEDQNKIQFSKGNKVIDVN
EEEECCCCCCEEEECCCCEEEECCCCEEEECC
>Mature Secondary Structure
MNIKLSFISIAFLSLSFNVAANEFEKSQEHYKSVTDLKNKIEILELEKKITELSGEIRNA
CCEEEHHHHHEEHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RMPKIDKSAPVLSPQPVVKSSEELQKSIEHIEEELKVELAYLVNNGQQKKYTFNLNGKLI
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHEEEECCCCCCEEEEECCCEEE
TLVNGDFVNGWKFIEDQNKIQFSKGNKVIDVN
EEEECCCCCCEEEECCCCEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8097178; 10952301