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The map label for this gene is tcpC

Identifier: 227081008

GI number: 227081008

Start: 850402

End: 851871

Strand: Direct

Name: tcpC

Synonym: VCM66_0788

Alternate gene names: 227081008

Gene position: 850402-851871 (Clockwise)

Preceding gene: 227081007

Following gene: 227081009

Centisome position: 29.4

GC content: 35.71

Gene sequence:

>1470_bases
ATGAAAAAAACAATAATCAGTACACTTGTTATCGGTTTGGTTTCCGGTTGTTCTAATACGAACTTGCTAAAAGACAATCT
GGCTAGCGAGCAAAGTGTTATCAATTTGAGTAAGTCTTCAAACGAAGCGAAATCTAGAAATATTGAATTTCTCTCTGGTG
CCTATTTAAGTGAGAGAAAAGTGCCAAAGCATGACATTAAGTTCAGTGGTAAGTATGTTGAGTTTGAAAGTAAATCACCG
ATAGAGTTAATCGATGTTCTTGATGGACTTTCTAAGCAATATAATATTCAGTATGTATTCTCAGATGAGTTAGAAGATGA
AAATTCAGAAGAAAATAAAAAGTCATCAGGCTCATCATCGGCGAAGAAAATAAAATACTCAGGTCCTCTGGCTGGTTTTT
TTGATTATTTAAGTAGTGCATATAACATGCACTTTGAATTTGGTCATAATAACTTAGTTAAGGCATATCATTATAAAAAT
CAAGTTTTTAACCTCCAGCAATACTTTGATGATAATAAGTTTAGCTCATCAATGCAGATCGGCGGTACCAGTGGCACATC
AAGTGGTTTAAAAGGTACTGCAGATACGGCTATAGAATCTAATAGTTGGGAAAAAATCGATGAGTTTTTAAGTGCATCGT
TAGGTGAAACTGGAAAATTTACTATTTTTGAAGATTATTCACTAGTTACAGTAAAAGCTCGACCAGATAAGTTTTTATTG
TTACATACTTTCTTTGATAAGTTAATCAATGAGAGCAAGATGCAAATCGCGGTTGATTATAGAGTGGTATCTCTTAGTGA
AGAACGCTTAAATCAGTTAGCTGCCAAATTTGGTATTGAAAATGCAGGGAAATACAGTATTACCAGTGATATGGTCGATG
CGATCTCTTTAAGTCAAGTAGGGGGGGGGTTAGGCGCTTCATATCGCTCCGCCTCAGCAAGATTAGATGCAGTGGTTAAT
GAGTTATCACAGGAAGTAATGCATGAGGGGCATTTTATCGGTATCCCTAACAGAGTAATGCCACTAAATGTCACTACAAA
CTCGAAGTATATATCCTCAATCGAAACAACAAAAGATACCAATACTGATGAGGAAACGAGAACTGTCAAAGTTTCTGACT
TAGTAACTGGTTTTAGCATGATGGTTATGCCGAAAATCTTAGATGATGGACGAATTCAAATATCGTCTGGCTTTTCAAGA
AAACAGTTAGTGTCTATTGGTACTGCACAAGGTATTACTCTACCAACAGTTGATGAAAATGAATCAATGAATACAGTAAC
GATGAACCCTGGTGAAGTACGCCTAGCAATGCTATTTAAGGATAACTACATTCAGAATAGTAATGGTGTTCAATTATTAG
GTGGTGGTACTGAAAATAAGAAATCGGCTCGTTATATTGCTGTGCTTGTTGGTGCAAGCAGTTACAAAACCAATGATCTG
GCTAGTAATAGAGTAAATATATATGACTAG

Upstream 100 bases:

>100_bases
TAACTGAGTTGGCTAGCGATATTAACCAAATTGGCATAGACATTAACTTTAAAATATTTCAAAAAAATAAAGTTATTGTC
GTCTATTCAGTGAGATAAGT

Downstream 100 bases:

>100_bases
CATATGGTTACATGAGTCAGATTTTAGATATGTTAACTTAGATGTAGAAAGATACCAAAAAAAATATCGTTTGACATTGA
CTAATGGAAATAAGTACGTA

Product: toxin co-regulated pilus biosynthesis outer membrane protein C

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpC

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MKKTIISTLVIGLVSGCSNTNLLKDNLASEQSVINLSKSSNEAKSRNIEFLSGAYLSERKVPKHDIKFSGKYVEFESKSP
IELIDVLDGLSKQYNIQYVFSDELEDENSEENKKSSGSSSAKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKN
QVFNLQQYFDDNKFSSSMQIGGTSGTSSGLKGTADTAIESNSWEKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQVGGGLGASYRSASARLDAVVN
ELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDTNTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSR
KQLVSIGTAQGITLPTVDENESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
ASNRVNIYD

Sequences:

>Translated_489_residues
MKKTIISTLVIGLVSGCSNTNLLKDNLASEQSVINLSKSSNEAKSRNIEFLSGAYLSERKVPKHDIKFSGKYVEFESKSP
IELIDVLDGLSKQYNIQYVFSDELEDENSEENKKSSGSSSAKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKN
QVFNLQQYFDDNKFSSSMQIGGTSGTSSGLKGTADTAIESNSWEKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQVGGGLGASYRSASARLDAVVN
ELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDTNTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSR
KQLVSIGTAQGITLPTVDENESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
ASNRVNIYD
>Mature_489_residues
MKKTIISTLVIGLVSGCSNTNLLKDNLASEQSVINLSKSSNEAKSRNIEFLSGAYLSERKVPKHDIKFSGKYVEFESKSP
IELIDVLDGLSKQYNIQYVFSDELEDENSEENKKSSGSSSAKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKN
QVFNLQQYFDDNKFSSSMQIGGTSGTSSGLKGTADTAIESNSWEKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQVGGGLGASYRSASARLDAVVN
ELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDTNTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSR
KQLVSIGTAQGITLPTVDENESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
ASNRVNIYD

Specific function: Involved in TCP pilus biogenesis

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Lipid-anchor

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TCPC_VIBCH (P29481)

Other databases:

- EMBL:   X64098
- EMBL:   AE003852
- EMBL:   X74730
- PIR:   B82275
- PIR:   PC4162
- PIR:   S23267
- RefSeq:   NP_230479.1
- GeneID:   2614498
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC0831
- TIGR:   VC_0831
- HOGENOM:   HBG739730
- OMA:   AIMISAR
- ProtClustDB:   CLSK793808
- InterPro:   IPR004846

Pfam domain/function: PF00263 Secretin

EC number: NA

Molecular weight: Translated: 53890; Mature: 53890

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x257f7284)-; HASH(0x25fdcf40)-; HASH(0x25d85c44)-; HASH(0x25fd4314)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIISTLVIGLVSGCSNTNLLKDNLASEQSVINLSKSSNEAKSRNIEFLSGAYLSERK
CCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHEEEECCCCCCHHHCCCEEEECCHHHCCC
VPKHDIKFSGKYVEFESKSPIELIDVLDGLSKQYNIQYVFSDELEDENSEENKKSSGSSS
CCCCCCEECCEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHCCCCCCC
AKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKNQVFNLQQYFDDNKFSSSMQI
CCEEEECCCHHHHHHHHHHHHEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEE
GGTSGTSSGLKGTADTAIESNSWEKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCCEEE
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQV
HHHHHHHHHCCCCEEEEEEEEEEEECHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
GGGLGASYRSASARLDAVVNELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCHHHHHHHCCCCC
NTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSRKQLVSIGTAQGITLPTVDEN
CCCCHHEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHEEECCCCCCCCCCCCCC
ESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
CCCCEEEECCCCEEEEEEEECCEEECCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCC
ASNRVNIYD
CCCCEEECH
>Mature Secondary Structure
MKKTIISTLVIGLVSGCSNTNLLKDNLASEQSVINLSKSSNEAKSRNIEFLSGAYLSERK
CCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHEEEECCCCCCHHHCCCEEEECCHHHCCC
VPKHDIKFSGKYVEFESKSPIELIDVLDGLSKQYNIQYVFSDELEDENSEENKKSSGSSS
CCCCCCEECCEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHCCCCCCC
AKKIKYSGPLAGFFDYLSSAYNMHFEFGHNNLVKAYHYKNQVFNLQQYFDDNKFSSSMQI
CCEEEECCCHHHHHHHHHHHHEEEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEE
GGTSGTSSGLKGTADTAIESNSWEKIDEFLSASLGETGKFTIFEDYSLVTVKARPDKFLL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCCCEEE
LHTFFDKLINESKMQIAVDYRVVSLSEERLNQLAAKFGIENAGKYSITSDMVDAISLSQV
HHHHHHHHHCCCCEEEEEEEEEEEECHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
GGGLGASYRSASARLDAVVNELSQEVMHEGHFIGIPNRVMPLNVTTNSKYISSIETTKDT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCHHHHHHHCCCCC
NTDEETRTVKVSDLVTGFSMMVMPKILDDGRIQISSGFSRKQLVSIGTAQGITLPTVDEN
CCCCHHEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHEEECCCCCCCCCCCCCC
ESMNTVTMNPGEVRLAMLFKDNYIQNSNGVQLLGGGTENKKSARYIAVLVGASSYKTNDL
CCCCEEEECCCCEEEEEEEECCEEECCCCEEEEECCCCCCCCCEEEEEEEECCCCCCCCC
ASNRVNIYD
CCCCEEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1358749; 10952301; 8621096