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The map label for this gene is yrbD [H]

Identifier: 227080963

GI number: 227080963

Start: 797890

End: 799440

Strand: Reverse

Name: yrbD [H]

Synonym: VCM66_0742

Alternate gene names: 227080963

Gene position: 799440-797890 (Counterclockwise)

Preceding gene: 227080964

Following gene: 227080961

Centisome position: 27.64

GC content: 50.42

Gene sequence:

>1551_bases
ATGCAGTCATTTGTTGATTTTCTGAATGGAATCATCTGGAGTCCGGCGCTGATTTATCTCTGCCTCGGTGCTGGCTTGTT
TTATTCCGTTCTGACTCGTTTTGTACAGGTTCGTCACTTCTTCGAAATGTGGCGCCTACTTCTGAATAATAAAGAGTCCT
CAAAAGGGATCTCCTCTTTCCAAGCGCTCGCCGTATCACTCTCAGGCCGTGTGGGTACCGGTAACATTGCTGGGGTTGCT
GCCGCTATCGGTTTCGGTGGCCCGGGTGCGGTATTCTGGATGTGGATGGTTGCGTTTTTTGGTGCCGCCACCGCGTATGC
AGAATCCACACTGGCGCAAATTTATAAAGAAGAAGACAACGGTGAATTCCGTGGCGGCCCCGCTTACTACATCGAAAAAG
CCATGGGTCAAAAATGGTACGCTTGGGTCTTCGCGATTGCGACCATCTTTGCTTGTGGGGTGTTGCTGCCTGGCGTGCAA
TCTAACAGTATCGGCAACGCCGTTGAGTCAGCATTTGGCTCAGGCCCAATGATTGAAACCGCACTCGGCACCTTTAGCTT
TGCCAAAATTTTCACCGGTACGGTGATTTCAATCCTACTTGGCTTCATTATCTTTGGTGGCGTAAAACGTATTGCAAGCT
TCACTCAGATCGTGGTGCCTTTTATGGCGCTGGCGTACATCATCACTGCGTTCGTGATCATTCTGCTCAACATCGGTGAA
GTTCCACGCATTATTGCGATGATCGTCGGCGACGCATTCTCACCGATGGCCGGCGTAGGTGCGGCGATTGGTTGGGGGGT
AAAACGTGGGGTTTACTCTAACGAAGCAGGTCAAGGTACTGGTCCACACGCCGCAGCGGCAGCCAGTGTAGAACACCCTG
CGCAGCAAGGTTTGGTACAGTCTTTCTCTATCTACATTGATACCTTGATGGTCTGTTCTGCCACCGCGTTCATGATTTTG
ATCACCGGCGCTTACAACGTTCACGGTGCCGCTGAAGGCATGTTCCTTGTGCAAAACCTGCCAGCGGACATCATTGCCAG
CAGCCCAGCCTTTACCCAAATTGCGGTAGATAGTGCCCTCCCCGGCATTGGTAAACCGTTCGTGGCGTTTGCGTTGTTCT
TCTTCGCCTTTACTACAATTTTGGCTTACTACTACATCGCTGAGACTAACGTGGCCTATATCCGCCGTACCTTCAAAGTC
GATGGTTTGATGTTTGTGCTCAAACTTGTACTGATGGCATCGGTATTCTACGGCACAGTGAAAACCGCGAACTTGGCATG
GGCGCTGGGTGATGTCGGGGTAGGCTTAATGGCTTGGCTCAACATTGTCGGCATCATCATCATCTTCTTTATGTCTAAGC
CAACCATGGCGGCTTTGAAAGATTATGAAGATCAGCAAAAACAAGGTGTGACCGAATTTACCTTCAACCCAGTGAAGCTT
GGTATCAAAGGGGCGACGTACTGGGAAGGGAAATACCTTCGCAAAACGGGCAAAGCCCCAACCGCGGAAGTGAAAGAGAC
CCAAAGGGTAGAGCAAACTAGCTCACTATAA

Upstream 100 bases:

>100_bases
GCCAGATAAAAGAATTAACATTTGAGTTACAAAAAGATTAATATACCGAACACACAACAGACACAATAAACACAACAACT
CATTTACAGGGAAACTACTT

Downstream 100 bases:

>100_bases
GAAAAAGCAGTGAACACAACATAAATAAGTCAAAGGGTTAGCATTCGCTAACCCTTTATTTTTCAACTCAAGGTGAAGAT
TACTTCGTTTTCGGTTCGAT

Product: sodium/alanine symporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MQSFVDFLNGIIWSPALIYLCLGAGLFYSVLTRFVQVRHFFEMWRLLLNNKESSKGISSFQALAVSLSGRVGTGNIAGVA
AAIGFGGPGAVFWMWMVAFFGAATAYAESTLAQIYKEEDNGEFRGGPAYYIEKAMGQKWYAWVFAIATIFACGVLLPGVQ
SNSIGNAVESAFGSGPMIETALGTFSFAKIFTGTVISILLGFIIFGGVKRIASFTQIVVPFMALAYIITAFVIILLNIGE
VPRIIAMIVGDAFSPMAGVGAAIGWGVKRGVYSNEAGQGTGPHAAAAASVEHPAQQGLVQSFSIYIDTLMVCSATAFMIL
ITGAYNVHGAAEGMFLVQNLPADIIASSPAFTQIAVDSALPGIGKPFVAFALFFFAFTTILAYYYIAETNVAYIRRTFKV
DGLMFVLKLVLMASVFYGTVKTANLAWALGDVGVGLMAWLNIVGIIIIFFMSKPTMAALKDYEDQQKQGVTEFTFNPVKL
GIKGATYWEGKYLRKTGKAPTAEVKETQRVEQTSSL

Sequences:

>Translated_516_residues
MQSFVDFLNGIIWSPALIYLCLGAGLFYSVLTRFVQVRHFFEMWRLLLNNKESSKGISSFQALAVSLSGRVGTGNIAGVA
AAIGFGGPGAVFWMWMVAFFGAATAYAESTLAQIYKEEDNGEFRGGPAYYIEKAMGQKWYAWVFAIATIFACGVLLPGVQ
SNSIGNAVESAFGSGPMIETALGTFSFAKIFTGTVISILLGFIIFGGVKRIASFTQIVVPFMALAYIITAFVIILLNIGE
VPRIIAMIVGDAFSPMAGVGAAIGWGVKRGVYSNEAGQGTGPHAAAAASVEHPAQQGLVQSFSIYIDTLMVCSATAFMIL
ITGAYNVHGAAEGMFLVQNLPADIIASSPAFTQIAVDSALPGIGKPFVAFALFFFAFTTILAYYYIAETNVAYIRRTFKV
DGLMFVLKLVLMASVFYGTVKTANLAWALGDVGVGLMAWLNIVGIIIIFFMSKPTMAALKDYEDQQKQGVTEFTFNPVKL
GIKGATYWEGKYLRKTGKAPTAEVKETQRVEQTSSL
>Mature_516_residues
MQSFVDFLNGIIWSPALIYLCLGAGLFYSVLTRFVQVRHFFEMWRLLLNNKESSKGISSFQALAVSLSGRVGTGNIAGVA
AAIGFGGPGAVFWMWMVAFFGAATAYAESTLAQIYKEEDNGEFRGGPAYYIEKAMGQKWYAWVFAIATIFACGVLLPGVQ
SNSIGNAVESAFGSGPMIETALGTFSFAKIFTGTVISILLGFIIFGGVKRIASFTQIVVPFMALAYIITAFVIILLNIGE
VPRIIAMIVGDAFSPMAGVGAAIGWGVKRGVYSNEAGQGTGPHAAAAASVEHPAQQGLVQSFSIYIDTLMVCSATAFMIL
ITGAYNVHGAAEGMFLVQNLPADIIASSPAFTQIAVDSALPGIGKPFVAFALFFFAFTTILAYYYIAETNVAYIRRTFKV
DGLMFVLKLVLMASVFYGTVKTANLAWALGDVGVGLMAWLNIVGIIIIFFMSKPTMAALKDYEDQQKQGVTEFTFNPVKL
GIKGATYWEGKYLRKTGKAPTAEVKETQRVEQTSSL

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=491, Percent_Identity=35.8452138492872, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 55441; Mature: 55441

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCEEECCHHHHHCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure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CCCCCEEECCHHHHHCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]