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The map label for this gene is cutC

Identifier: 227080909

GI number: 227080909

Start: 743017

End: 743781

Strand: Reverse

Name: cutC

Synonym: VCM66_0688

Alternate gene names: 227080909

Gene position: 743781-743017 (Counterclockwise)

Preceding gene: 227080910

Following gene: 227080907

Centisome position: 25.71

GC content: 50.85

Gene sequence:

>765_bases
ATGAAATATCAAGTTGAAGTCTGTATCGACAATATCGAATCCCTGCATAACGCCATCGCGGGAGGCGCAACCCGTATTGA
GCTTTGTTCATCCCTTGCGCTAGGTGGATTAACCCCTAGTGCCGGGTTGATGTACAGCGCAGGCAGAGTGTCACCGATTC
CGGCTTACGCAATGATCAGACCAAGAGAAGGGGATTTTTTCTATCACGATGATGAACTCAGCATTATGGCGCAGGACATT
CGTACGGCGCATCAAGCAAACTTACAAGGCGTGGTACTAGGGTTACTCAATGCCGATGGCACGATTGATGTGAAACGCAG
CAAACCTTTAATCGAACTTGCTCACTCCCTCGGGTTAGGTGTGACGTTTCACCGCGCATTTGACCACTGTGTAAACCCTG
AACACGCGTTAGAAGAGATCATTGCGCTCGGTTGTGAACGCATTTTGACCTCAGGCTTGGCGCGCAACGCTTATCTGGGT
ATTGAACGTTTAGCGCAACTGGTCAAACAGAGTGCTGGGCGCATTTCAATCATGGCAGGCGCTGGGATCAATGCGCAGAA
TGTGGCTGAAATTGCGTTAGCCACCGGGGTCAATGAGCTGCATTTATCCGCGAAAACCACGCGTCCGAGCGAGATGCTGT
TTATTCGCTCGGAGAGCAAAATGGGCGCGGCGGACTGTGATGATTTTATTATCCCGGTGACCAGCCGCGATGCGTTACAG
CAAACCGTACACGCTCTGGCAGCACTCAATTCTGTCCTACATTAA

Upstream 100 bases:

>100_bases
GGTAATTCGGGTCTTAAACTTTACCCCTATTCTTGCGCATTCTGCGCGATATCTGCTGCTATGATACTGCCATTTCCTTT
ATCCAACCGGAGTTAACCTG

Downstream 100 bases:

>100_bases
TGATGTATACCCAAACGACTTGGCGTTGCAGGTAGGCGGCAAGTGAGTTCATCCCCATGAGCATAGATAAACGATGTGAT
TGGGGTGAACGAACGTAGCC

Product: copper homeostasis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKYQVEVCIDNIESLHNAIAGGATRIELCSSLALGGLTPSAGLMYSAGRVSPIPAYAMIRPREGDFFYHDDELSIMAQDI
RTAHQANLQGVVLGLLNADGTIDVKRSKPLIELAHSLGLGVTFHRAFDHCVNPEHALEEIIALGCERILTSGLARNAYLG
IERLAQLVKQSAGRISIMAGAGINAQNVAEIALATGVNELHLSAKTTRPSEMLFIRSESKMGAADCDDFIIPVTSRDALQ
QTVHALAALNSVLH

Sequences:

>Translated_254_residues
MKYQVEVCIDNIESLHNAIAGGATRIELCSSLALGGLTPSAGLMYSAGRVSPIPAYAMIRPREGDFFYHDDELSIMAQDI
RTAHQANLQGVVLGLLNADGTIDVKRSKPLIELAHSLGLGVTFHRAFDHCVNPEHALEEIIALGCERILTSGLARNAYLG
IERLAQLVKQSAGRISIMAGAGINAQNVAEIALATGVNELHLSAKTTRPSEMLFIRSESKMGAADCDDFIIPVTSRDALQ
QTVHALAALNSVLH
>Mature_254_residues
MKYQVEVCIDNIESLHNAIAGGATRIELCSSLALGGLTPSAGLMYSAGRVSPIPAYAMIRPREGDFFYHDDELSIMAQDI
RTAHQANLQGVVLGLLNADGTIDVKRSKPLIELAHSLGLGVTFHRAFDHCVNPEHALEEIIALGCERILTSGLARNAYLG
IERLAQLVKQSAGRISIMAGAGINAQNVAEIALATGVNELHLSAKTTRPSEMLFIRSESKMGAADCDDFIIPVTSRDALQ
QTVHALAALNSVLH

Specific function: Involved in copper homeostasis

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family

Homologues:

Organism=Homo sapiens, GI148596990, Length=246, Percent_Identity=42.6829268292683, Blast_Score=189, Evalue=2e-48,
Organism=Escherichia coli, GI87081995, Length=210, Percent_Identity=39.5238095238095, Blast_Score=150, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17556905, Length=223, Percent_Identity=38.1165919282511, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21355415, Length=209, Percent_Identity=39.7129186602871, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CUTC_VIBC3 (A5F8U2)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F8U2
- SMR:   A5F8U2
- STRING:   A5F8U2
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0263
- eggNOG:   COG3142
- HOGENOM:   HBG535337
- OMA:   PVYAMIR
- ProtClustDB:   CLSK874089
- BioCyc:   VCHO345073:VC0395_A0263-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00795
- InterPro:   IPR005627
- Gene3D:   G3DSA:3.20.20.380
- PANTHER:   PTHR12598

Pfam domain/function: PF03932 CutC; SSF110395 CutC

EC number: NA

Molecular weight: Translated: 27193; Mature: 27193

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQVEVCIDNIESLHNAIAGGATRIELCSSLALGGLTPSAGLMYSAGRVSPIPAYAMIR
CCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEE
PREGDFFYHDDELSIMAQDIRTAHQANLQGVVLGLLNADGTIDVKRSKPLIELAHSLGLG
CCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCHHHHHHHHCCC
VTFHRAFDHCVNPEHALEEIIALGCERILTSGLARNAYLGIERLAQLVKQSAGRISIMAG
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
AGINAQNVAEIALATGVNELHLSAKTTRPSEMLFIRSESKMGAADCDDFIIPVTSRDALQ
CCCCHHHHHHHHHHCCCHHEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEECCCHHHHH
QTVHALAALNSVLH
HHHHHHHHHHHHCC
>Mature Secondary Structure
MKYQVEVCIDNIESLHNAIAGGATRIELCSSLALGGLTPSAGLMYSAGRVSPIPAYAMIR
CCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCEEEEE
PREGDFFYHDDELSIMAQDIRTAHQANLQGVVLGLLNADGTIDVKRSKPLIELAHSLGLG
CCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCHHHHHHHHCCC
VTFHRAFDHCVNPEHALEEIIALGCERILTSGLARNAYLGIERLAQLVKQSAGRISIMAG
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
AGINAQNVAEIALATGVNELHLSAKTTRPSEMLFIRSESKMGAADCDDFIIPVTSRDALQ
CCCCHHHHHHHHHHCCCHHEEEEECCCCCCEEEEEECCCCCCCCCCCCEEEECCCHHHHH
QTVHALAALNSVLH
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA