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The map label for this gene is mviN

Identifier: 227080861

GI number: 227080861

Start: 683490

End: 685067

Strand: Direct

Name: mviN

Synonym: VCM66_0638

Alternate gene names: 227080861

Gene position: 683490-685067 (Clockwise)

Preceding gene: 227080859

Following gene: 227080862

Centisome position: 23.63

GC content: 48.23

Gene sequence:

>1578_bases
TTGTTCGAGGTTACCGTGAGTAAACGCTTACTCAAGTCTGGCATCATTGTAAGTGCTATGACTTTGATTTCTCGTGTTTT
AGGTTTAGTGCGCGATGTGGTTGTGGCCAATTTGATGGGCGCAGGTGCCAGTGCTGACGTATTCTTTTTTGCCAACCGAA
TTCCCAATTTTTTACGCCGATTATTTGCAGAAGGGGCCTTCTCTCAAGCATTTGTCCCGGTCTTAACCGAATATCACGCC
TCGGGTGATATCAATAAAACTCGAGATTTAATTGCGCGAGCGTCGGGAACTCTCGGTGTTTTAGTGACCATAGTGACGCT
AATTGGCGTGCTCGGCTCTGGCGCAGTCACCGCATTATTTGGCGCAGGTTGGTTCTTAGACTGGCTGAATGGGGGGCCTG
CAGCAGGAAAGTTTGAGTTAGCGAGCTTACTGCTCAAGATTACTTTTCCCTATTTGTGGTTTATCACCTTTGTTGCCTTG
TCTGGGGCAATTTTAAACACCTTAGGTAAGTTTGCCGTCTCCTCTTTCACGCCAGTTTTCTTGAACGTGATGATGATTCT
GTGTGCTTGGTACCTCTCGCCAAATCTAGAACAGCCGGAAGTGGGCTTAGCAATAGGCGTATTTTTAGGTGGTTTAGTCC
AGTTTTTATTTCAACTGCCATTTTTGATCAAGGCTGGAGTGCTGGTTAGGCCTAAATGGGGCTGGAAAGATCCTGGGGTG
GTGAAAATTCGCACACTGATGATTCCTGCACTGTTTGGAGTATCGGTCAGTCAAATCAACTTGTTATTTGACTCCTTCGT
GGCCAGTTTTCTGCAAACCGGTTCGATCAGCTGGCTCTATTATTCGGATCGCCTGCTGGAGTTTCCCCTCGGTTTATTTG
GGATTGCGATTGCCACAGTAATTTTGCCTGCCTTATCGCGTAAACATGTTGATGCGCACAGTGATGGCTTTGCCCACACC
ATGGACTGGGGGATTCGCATGGTCACGTTTCTCGGCATTCCTGCCATGCTGGGTTTGATGGTACTGGCAAAACCTATGTT
GATGGTGCTGTTTATGCGCGGGGAATTTACTCCAAGCGATGTAGAGCAAGCGTCCTATTCGTTACTCGCTTACTCATCTG
GCCTGCTCAGCTTTATGTTGATCAAAGTGTTAGCGCCGGGATATTACTCACGTCAAGACACGAAAACCCCCGTACGTTAC
GGAATTATCGCTATGGTCAGCAATATTGTGCTTAACGCGATCTTTGCGTGGTTTTACGGCTATGTTGGCTTGGCGGTCGC
GACTTCGATGTCCGCTTTCCTCAATATGGCACTGCTTTATCGTGGTTTGCACTTACAAGGTGTTTATCATCTGACTCGCA
AAACCGTCTGGTTTGTTGCGCGACTGGCGATGGCGGGAGCGGTAATGACTGGTGCGCTTTTGTGGCAGTTAGACACTATG
GCTACATGGCTGAGCTGGGGAATCAGTCAGCGCGCATTGACGCTGACAGGCTTGATTGGCCTTGGCGTGGCATCTTATCT
GGCTATTTTGCTGTTACTGGGTGTTCGTCTCAAAGATCTAAAAGCGGCGACAGAGTAG

Upstream 100 bases:

>100_bases
GGCGGGGATTCTATCAGCATTTTTTTACCAATGCTAATACTTATCTGATCTCACTATGACATTCTTATCCTTTCGAATCA
GATAATGTGGTTTTGACTCT

Downstream 100 bases:

>100_bases
CGAGCTTTAGGTATAATCCGCCAGTTTCGCACCATGAGAATCAAAATATAGGTTTTAAGCATCTTCCGATGGAATTAATA
CGCGGTATTCATAACATTCA

Product: MviN protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MFEVTVSKRLLKSGIIVSAMTLISRVLGLVRDVVVANLMGAGASADVFFFANRIPNFLRRLFAEGAFSQAFVPVLTEYHA
SGDINKTRDLIARASGTLGVLVTIVTLIGVLGSGAVTALFGAGWFLDWLNGGPAAGKFELASLLLKITFPYLWFITFVAL
SGAILNTLGKFAVSSFTPVFLNVMMILCAWYLSPNLEQPEVGLAIGVFLGGLVQFLFQLPFLIKAGVLVRPKWGWKDPGV
VKIRTLMIPALFGVSVSQINLLFDSFVASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSDGFAHT
MDWGIRMVTFLGIPAMLGLMVLAKPMLMVLFMRGEFTPSDVEQASYSLLAYSSGLLSFMLIKVLAPGYYSRQDTKTPVRY
GIIAMVSNIVLNAIFAWFYGYVGLAVATSMSAFLNMALLYRGLHLQGVYHLTRKTVWFVARLAMAGAVMTGALLWQLDTM
ATWLSWGISQRALTLTGLIGLGVASYLAILLLLGVRLKDLKAATE

Sequences:

>Translated_525_residues
MFEVTVSKRLLKSGIIVSAMTLISRVLGLVRDVVVANLMGAGASADVFFFANRIPNFLRRLFAEGAFSQAFVPVLTEYHA
SGDINKTRDLIARASGTLGVLVTIVTLIGVLGSGAVTALFGAGWFLDWLNGGPAAGKFELASLLLKITFPYLWFITFVAL
SGAILNTLGKFAVSSFTPVFLNVMMILCAWYLSPNLEQPEVGLAIGVFLGGLVQFLFQLPFLIKAGVLVRPKWGWKDPGV
VKIRTLMIPALFGVSVSQINLLFDSFVASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSDGFAHT
MDWGIRMVTFLGIPAMLGLMVLAKPMLMVLFMRGEFTPSDVEQASYSLLAYSSGLLSFMLIKVLAPGYYSRQDTKTPVRY
GIIAMVSNIVLNAIFAWFYGYVGLAVATSMSAFLNMALLYRGLHLQGVYHLTRKTVWFVARLAMAGAVMTGALLWQLDTM
ATWLSWGISQRALTLTGLIGLGVASYLAILLLLGVRLKDLKAATE
>Mature_525_residues
MFEVTVSKRLLKSGIIVSAMTLISRVLGLVRDVVVANLMGAGASADVFFFANRIPNFLRRLFAEGAFSQAFVPVLTEYHA
SGDINKTRDLIARASGTLGVLVTIVTLIGVLGSGAVTALFGAGWFLDWLNGGPAAGKFELASLLLKITFPYLWFITFVAL
SGAILNTLGKFAVSSFTPVFLNVMMILCAWYLSPNLEQPEVGLAIGVFLGGLVQFLFQLPFLIKAGVLVRPKWGWKDPGV
VKIRTLMIPALFGVSVSQINLLFDSFVASFLQTGSISWLYYSDRLLEFPLGLFGIAIATVILPALSRKHVDAHSDGFAHT
MDWGIRMVTFLGIPAMLGLMVLAKPMLMVLFMRGEFTPSDVEQASYSLLAYSSGLLSFMLIKVLAPGYYSRQDTKTPVRY
GIIAMVSNIVLNAIFAWFYGYVGLAVATSMSAFLNMALLYRGLHLQGVYHLTRKTVWFVARLAMAGAVMTGALLWQLDTM
ATWLSWGISQRALTLTGLIGLGVASYLAILLLLGVRLKDLKAATE

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family

Homologues:

Organism=Escherichia coli, GI1787309, Length=516, Percent_Identity=41.6666666666667, Blast_Score=384, Evalue=1e-107,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): MVIN_VIBCH (O34238)

Other databases:

- EMBL:   AJ002395
- EMBL:   AE003852
- PIR:   B82293
- RefSeq:   NP_230329.1
- GeneID:   2615469
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC0680
- TIGR:   VC_0680
- HOGENOM:   HBG731814
- OMA:   MLKITFP
- ProtClustDB:   CLSK870564
- InterPro:   IPR004268
- PRINTS:   PR01806
- TIGRFAMs:   TIGR01695

Pfam domain/function: PF03023 MVIN

EC number: NA

Molecular weight: Translated: 57154; Mature: 57154

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2594e1c4)-; HASH(0x25b7ae4c)-; HASH(0x25b64b68)-; HASH(0x23e2882c)-; HASH(0x25a9075c)-; HASH(0x258eda80)-; HASH(0x258edb1c)-; HASH(0x25b7ad20)-; HASH(0x25284714)-; HASH(0x2580b054)-; HASH(0x250dca40)-; HASH(0x257cd618)-; HASH(0x25b971e8)-; HASH(0x23be63b8)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCH
>Mature Secondary Structure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HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9457888; 10952301