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The map label for this gene is nlpI [H]

Identifier: 227080829

GI number: 227080829

Start: 649938

End: 650849

Strand: Direct

Name: nlpI [H]

Synonym: VCM66_0606

Alternate gene names: 227080829

Gene position: 649938-650849 (Clockwise)

Preceding gene: 227080828

Following gene: 227080830

Centisome position: 22.47

GC content: 49.89

Gene sequence:

>912_bases
GTGAAATGGTTTCGATTCCCGATAGCGGTGATAGGATTGGTTCTGCTGTCAGGGTGTGCCACGCAGAATGAATCTGCAAC
CCAATGGCTTTACCCGCCAATGGCGGTGCCGCTGCAAGCGTCGATTCAACAAGAAGTGCAAATCGCCCGCTTAAGCCAAT
TATTACAGCGCACGGATCTTGAGCCTGAGATACGCGCTAAAATGCTGTTCGAACGTGGCAATTATTACGACAGTGTCGGT
TTACGTGATTTGGCTCGGCTCGATTTTACTCAATCGCTCTCGATTAACCCTGCGCAGCCCGATGTGTTTAACTTGCTAGG
GGTGTATTACACCGAAGCGGGCGAGTTTGACGCCGCGTATGAATCCTTCGATTCGACGTTAGAATTGGATCCTAGTAACG
AGTATGCCGTGCGCAATCGCGCCATCGCGCTTTACTATGGCGAGCGCCCACAACTGGCACTCGAAGAGATCACTAAGCAC
TATCAGCAAGACCCACAAGATCCTTTTCGGGCGCTGTGGCTGTACATCATAGAAAGCGATATTGACCCGACAAAAGCGCG
TACAGAATTGCTTGAACGCTATCAGCAGCACGATGAACAGTGGGGCTGGGTGTTGGTAGGACTGATGCTGGATCAACTCT
CGGAAGAGGTCGCATTCAAAGCCATTATTGCGGGCTCTCGAGAAAATGAGCTATTAGCACAGCGTCTCACTGAGGCTTAT
TTCTACCTAGGTAAGCGTTATCAAATGCAAGGAGAACTGGCCCATGCTCTCTCTTTGTATAAGCTCGCGATTTCCTTTAA
TGTGTATGAATATGTGGAGCATCGCTATGCTTTTCTTGAGCTAGGGCGCATCTATCAACAAGCCCGTGAAGAGCAGTTAG
CGCGCGCGAAAGCCGAAGCAATGACACAATAG

Upstream 100 bases:

>100_bases
GCAAAAACAACACGGCTTTTACTTTTCATAATAAAAGCGTGCTATAAAGGGAGCGTTATTCGCTCCCTTTTTTATGCGAA
ATCCCACAGGAGTATGATGA

Downstream 100 bases:

>100_bases
TTTCACCTCTCTCTGATAAAAAAGCCGCATCTTGCGGCTTTTTTTGTTGCTAGGACTCTGGCAGAATAGTTAGCCTTGCT
AACTATGTGTTATCGAATAT

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDLEPEIRAKMLFERGNYYDSVG
LRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAYESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKH
YQQDPQDPFRALWLYIIESDIDPTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGRIYQQAREEQLARAKAEAMTQ

Sequences:

>Translated_303_residues
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDLEPEIRAKMLFERGNYYDSVG
LRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAYESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKH
YQQDPQDPFRALWLYIIESDIDPTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGRIYQQAREEQLARAKAEAMTQ
>Mature_303_residues
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDLEPEIRAKMLFERGNYYDSVG
LRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAYESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKH
YQQDPQDPFRALWLYIIESDIDPTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGRIYQQAREEQLARAKAEAMTQ

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=288, Percent_Identity=48.2638888888889, Blast_Score=261, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 35151; Mature: 35151

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDL
CCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
EPEIRAKMLFERGNYYDSVGLRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAY
CHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
ESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKHYQQDPQDPFRALWLYIIESD
HHCCCEEEECCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
IDPTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGRIYQQAREEQLARAKAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTQ
CCC
>Mature Secondary Structure
MKWFRFPIAVIGLVLLSGCATQNESATQWLYPPMAVPLQASIQQEVQIARLSQLLQRTDL
CCCCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
EPEIRAKMLFERGNYYDSVGLRDLARLDFTQSLSINPAQPDVFNLLGVYYTEAGEFDAAY
CHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
ESFDSTLELDPSNEYAVRNRAIALYYGERPQLALEEITKHYQQDPQDPFRALWLYIIESD
HHCCCEEEECCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
IDPTKARTELLERYQQHDEQWGWVLVGLMLDQLSEEVAFKAIIAGSRENELLAQRLTEAY
CCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FYLGKRYQMQGELAHALSLYKLAISFNVYEYVEHRYAFLELGRIYQQAREEQLARAKAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]