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The map label for this gene is glmM [H]

Identifier: 227080820

GI number: 227080820

Start: 638436

End: 639776

Strand: Direct

Name: glmM [H]

Synonym: VCM66_0597

Alternate gene names: 227080820

Gene position: 638436-639776 (Clockwise)

Preceding gene: 227080819

Following gene: 227080821

Centisome position: 22.07

GC content: 47.8

Gene sequence:

>1341_bases
ATGTCTGATAAGAGACGTTATTTTGGCACTGATGGGGTTCGTGGCAAAGTTGGCCAGTACCCAATTACTCCTGATTTTGT
ACTTAAGCTTGGCTGGGCGGCTGGACGTGTACTGGCAAAACAAGGCACGAGAAAAGTCATTATTGGTAAAGATACCCGTA
TTTCTGGCTATATGTTGGAGTCTGCACTGGAAGCTGGGCTTGCAGCGGCAGGATTAAAAGCGACCTTCACCGGACCAATG
CCAACGCCAGCTGTGGCCTATCTTACCCAAACGTTTCGTGCAGAAGCGGGGATTGTTATTTCTGCATCGCACAACCCTTA
CTACGATAACGGCATTAAGTTCTTCTCTTATGAAGGAACCAAACTGCCGGATGACATTGAGTTAGCGATTGAAGCTGAGT
TAGATAAAGACATTGAATGTGTTGAATCGGCTGAGCTTGGTAAAGCTTCACGCATGGTGGATGCGGCGGGGCGTTACATC
GAATTTTGTAAAAGCACTTTCCCTTCAAAACTCAGTCTATCTGGTTTGAAGCTTGTTGTGGATTGTGCCAATGGTGCCAC
ATACCACATTGCGCCCAATGTTTTCCGTGAGTTGGGAGCGGAAGTCATTGCGATGGGCGTTGAGCCTAATGGTTTGAATA
TCAATGACCAAGTCGGTGCAACCGACGTTCGCGCACTGCAAAAACGCGTTGTTGAAGAGCATGCTCATCTTGGCCTTGCT
TTCGATGGTGACGGCGACCGCATCATCATGGTTGATCACCTAGGTAATAAAGTCGATGGTGACCAAATCGCTTACATTAT
TGCCCGTGATGCACTGCGCCGTGGCGAGCTCAAAGGTGGCGTTGTTGGGACATTGATGACGAACCTTGGCATGGAGAATG
GACTTAAACAGTTGGGCATTCCATTTGTACGCGCTGCGGTCGGTGATCGCTATGTTATGGAAAAACTTCTAGAGAAAGGC
TGGAAGATTGGTGCGGAAAATTCAGGTCACGTCATCTTACTCGATAAAGTGACTACGGGGGATGCGATTGTCGCTGGCCT
ACAAGTGCTGGCTTCAGTAGTGGGTAGTGAAATGACCCTGCATGAATTAGCGAAAGGTATGACGCTTTACCCACAAGTGT
TGGAGAATGTCCGTTTTGCAGGAGATAACAATCCACTTGAAGCGGATGCGGTGAAAGCGGCGGTATCTGAGGTTGAAGCT
GAGCTAGGTTCGAAAGGCCGTGTATTACTGCGCAAATCGGGTACAGAACCTCTGATCCGTGTGATGGTGGAAGGGGAAGA
TGAAACCTTAGTGAAGCAATCTGCATTAAAAATTGCTCAAGCTGTAAAAGATAACTGCTAA

Upstream 100 bases:

>100_bases
ATTATCCGTGTTCATGATGTAGAGCAGACCATTGATGCACTCAAAATGGTGCAGATGATGCATAACAATTTGTAAAAACA
ATAATGTAAAGGAAACACAA

Downstream 100 bases:

>100_bases
TTTGGGCGCTGGTTTCTACAATTCCTAGCTGATTGATTTCGCGCTAGGAATTGTAGAAATGCTCGAAAAAACGCTGTTGT
GCGAGTTTTTTGAGCGATCA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLESALEAGLAAAGLKATFTGPM
PTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGTKLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYI
EFCKSTFPSKLSLSGLKLVVDCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLA
FDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEKLLEKG
WKIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTLHELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEA
ELGSKGRVLLRKSGTEPLIRVMVEGEDETLVKQSALKIAQAVKDNC

Sequences:

>Translated_446_residues
MSDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLESALEAGLAAAGLKATFTGPM
PTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGTKLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYI
EFCKSTFPSKLSLSGLKLVVDCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLA
FDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEKLLEKG
WKIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTLHELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEA
ELGSKGRVLLRKSGTEPLIRVMVEGEDETLVKQSALKIAQAVKDNC
>Mature_445_residues
SDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLESALEAGLAAAGLKATFTGPMP
TPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGTKLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYIE
FCKSTFPSKLSLSGLKLVVDCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLAF
DGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEKLLEKGW
KIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTLHELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEAE
LGSKGRVLLRKSGTEPLIRVMVEGEDETLVKQSALKIAQAVKDNC

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1789566, Length=441, Percent_Identity=76.6439909297052, Blast_Score=679, Evalue=0.0,
Organism=Escherichia coli, GI1788361, Length=445, Percent_Identity=24.9438202247191, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6323752, Length=393, Percent_Identity=24.9363867684478, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 47849; Mature: 47717

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
SALEAGLAAAGLKATFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGT
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCC
KLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYIEFCKSTFPSKLSLSGLKLVV
CCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
DCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLA
ECCCCCEEEECHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEE
FDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGI
EECCCCEEEEEECCCCCCCCCCEEEHEEHHHHHHCCCCCCHHHHHHHHCCHHCCHHHHCC
PFVRAAVGDRYVMEKLLEKGWKIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHH
HELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEAELGSKGRVLLRKSGTEPLIR
HHHHCCCCHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
VMVEGEDETLVKQSALKIAQAVKDNC
EEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLE
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHH
SALEAGLAAAGLKATFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGT
HHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCC
KLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYIEFCKSTFPSKLSLSGLKLVV
CCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
DCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLA
ECCCCCEEEECHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEE
FDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGI
EECCCCEEEEEECCCCCCCCCCEEEHEEHHHHHHCCCCCCHHHHHHHHCCHHCCHHHHCC
PFVRAAVGDRYVMEKLLEKGWKIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTL
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHH
HELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEAELGSKGRVLLRKSGTEPLIR
HHHHCCCCHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEE
VMVEGEDETLVKQSALKIAQAVKDNC
EEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA