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The map label for this gene is surE

Identifier: 227080714

GI number: 227080714

Start: 519760

End: 520551

Strand: Direct

Name: surE

Synonym: VCM66_0489

Alternate gene names: 227080714

Gene position: 519760-520551 (Clockwise)

Preceding gene: 227080713

Following gene: 227080715

Centisome position: 17.97

GC content: 49.87

Gene sequence:

>792_bases
ATGAACAAGAGAGCCGCGATTCAGAGAGCGAAGATTAAGATGAAGATTCTACTCAGTAACGATGATGGCGTTTACGCACA
AGGCATTCATGCTTTGGCGGATGCATTGCGTGATTTAGCGGAGATTGTGATTGTCGCGCCGGATCGTAACCGCAGTGGTG
CCTCGAATTCACTGACCTTAGAGCATCCATTACGAGTGTCGCAAATTGCCGAGAATACCTATTCCGTGCAAGGTACCCCG
ACTGATTGCGTGCACTTTGCGCTTAATGAACTGATGAAAGACGCGCTACCGGATCTGGTACTGAGCGGAATCAATCACGG
AGCTAACTTGGGTGATGATGTGCTCTATTCCGGTACGGTGGCGGCGGCAATGGAAGGGCATTTTCTTGGCGTGCAGTCGA
TCGCCTTTTCTCTGGCGGGAACTACTCATTTTGCTAGTGCTGCTCACTTTGTGCGTCAATTGGTCGAGCAACATCTGGCT
AACCCGATTCCGACCAATCGCTTACTTAACGTGAATATTCCGGATCGACCTTTAGAACTCATTCAAGGTATTGAAGTCAC
ACGCTTAGGTGCGCGGCATCACGCCGAAAGCATGATAAAGCAGAAAGATCCGCGTGGGCATGATATTTATTGGCTTGGTC
CTCCGGGTAAAGAGCAAGATGCCGGTCCGGGAACGGATTTTCATGCGATTGAACGTGGCTGGGTGTCACTCACGCCGCTA
CAAGTTGACCTAACGGCACATGAGTCACTGCGTAGCATGGATCATTGGTTAAAGGAAAAGGTGAATGGCTAA

Upstream 100 bases:

>100_bases
ATCACTCTGCGTTTCTCATTGGATGCGGGTAGCTTTGCCACTTCCTTAGTGCGTGAATTGATCGAAGAGATCCCAGTGGT
GCGTCATTACGATCAAGGCC

Downstream 100 bases:

>100_bases
CCCAAAAGCCGACAGACTGATTCAATTTTTAACTGAGCAGGGGATTACCTCACCACAAGTGTTGGCGGCAATCCATGCAC
TGCCACGCGAGTTTTTCGTC

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MNKRAAIQRAKIKMKILLSNDDGVYAQGIHALADALRDLAEIVIVAPDRNRSGASNSLTLEHPLRVSQIAENTYSVQGTP
TDCVHFALNELMKDALPDLVLSGINHGANLGDDVLYSGTVAAAMEGHFLGVQSIAFSLAGTTHFASAAHFVRQLVEQHLA
NPIPTNRLLNVNIPDRPLELIQGIEVTRLGARHHAESMIKQKDPRGHDIYWLGPPGKEQDAGPGTDFHAIERGWVSLTPL
QVDLTAHESLRSMDHWLKEKVNG

Sequences:

>Translated_263_residues
MNKRAAIQRAKIKMKILLSNDDGVYAQGIHALADALRDLAEIVIVAPDRNRSGASNSLTLEHPLRVSQIAENTYSVQGTP
TDCVHFALNELMKDALPDLVLSGINHGANLGDDVLYSGTVAAAMEGHFLGVQSIAFSLAGTTHFASAAHFVRQLVEQHLA
NPIPTNRLLNVNIPDRPLELIQGIEVTRLGARHHAESMIKQKDPRGHDIYWLGPPGKEQDAGPGTDFHAIERGWVSLTPL
QVDLTAHESLRSMDHWLKEKVNG
>Mature_263_residues
MNKRAAIQRAKIKMKILLSNDDGVYAQGIHALADALRDLAEIVIVAPDRNRSGASNSLTLEHPLRVSQIAENTYSVQGTP
TDCVHFALNELMKDALPDLVLSGINHGANLGDDVLYSGTVAAAMEGHFLGVQSIAFSLAGTTHFASAAHFVRQLVEQHLA
NPIPTNRLLNVNIPDRPLELIQGIEVTRLGARHHAESMIKQKDPRGHDIYWLGPPGKEQDAGPGTDFHAIERGWVSLTPL
QVDLTAHESLRSMDHWLKEKVNG

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=247, Percent_Identity=56.2753036437247, Blast_Score=283, Evalue=9e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_VIBC3 (A5F9D9)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F9D9
- SMR:   A5F9D9
- STRING:   A5F9D9
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A0059
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- ProtClustDB:   PRK00346
- BioCyc:   VCHO345073:VC0395_A0059-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 28723; Mature: 28723

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKRAAIQRAKIKMKILLSNDDGVYAQGIHALADALRDLAEIVIVAPDRNRSGASNSLTL
CCCHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEE
EHPLRVSQIAENTYSVQGTPTDCVHFALNELMKDALPDLVLSGINHGANLGDDVLYSGTV
CCCCHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHH
AAAMEGHFLGVQSIAFSLAGTTHFASAAHFVRQLVEQHLANPIPTNRLLNVNIPDRPLEL
HHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHH
IQGIEVTRLGARHHAESMIKQKDPRGHDIYWLGPPGKEQDAGPGTDFHAIERGWVSLTPL
HCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCEEECEE
QVDLTAHESLRSMDHWLKEKVNG
EEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKRAAIQRAKIKMKILLSNDDGVYAQGIHALADALRDLAEIVIVAPDRNRSGASNSLTL
CCCHHHHHHHEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEE
EHPLRVSQIAENTYSVQGTPTDCVHFALNELMKDALPDLVLSGINHGANLGDDVLYSGTV
CCCCHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHH
AAAMEGHFLGVQSIAFSLAGTTHFASAAHFVRQLVEQHLANPIPTNRLLNVNIPDRPLEL
HHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHH
IQGIEVTRLGARHHAESMIKQKDPRGHDIYWLGPPGKEQDAGPGTDFHAIERGWVSLTPL
HCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHCCCEEECEE
QVDLTAHESLRSMDHWLKEKVNG
EEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA