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The map label for this gene is ssb

Identifier: 227080608

GI number: 227080608

Start: 407341

End: 407874

Strand: Direct

Name: ssb

Synonym: VCM66_0382

Alternate gene names: 227080608

Gene position: 407341-407874 (Clockwise)

Preceding gene: 227080603

Following gene: 227080609

Centisome position: 14.08

GC content: 49.81

Gene sequence:

>534_bases
ATGGCAAGCCGTGGCGTGAACAAAGTAATTTTGATTGGTAACTTAGGCCAAGATCCTGAAGTGCGTTATATGCCAAGCGG
CGGCGCAGTAGCGAATATCACCATCGCGACCTCCGAAACCTGGCGTGATAAAGCCACAGGTGAACAGAAGGAAAAAACCG
AATGGCACCGAGTTACTCTGTATGGAAAATTGGCAGAAGTGGCTGGTGAATATTTGCGTAAAGGTTCTCAAGTTTACATT
GAAGGCCAACTGCAAACGCGTAAGTGGCAAGATCAAAGTGGTCAAGATCGCTACTCAACCGAAGTGGTTGTACAAGGCTA
TAACGGTATCATGCAGATGCTGGGTGGACGTGCACAGCAAGGTGGAATGCCAGCCCAAGGCGGCATGAATGTTCCTGCGC
AGCAAGGAAGTTGGGGACAACCACAACAACCGGCGAAGCAGCATCAGCCTATGCAACAATCTGCGCCTCAACAGTACTCG
CAACCGCAGTATAATGAGCCGCCGATGGATTTTGATGACGACATCCCGTTTTAG

Upstream 100 bases:

>100_bases
CCATCAGAATAAGGGAATTCGATTGGTTCAGTGAGCAAAACGGTGTTATCCTTGCCGACTACTTCAAATTGATAGACATG
ACTTGATTACGGAGCAAAAC

Downstream 100 bases:

>100_bases
TATTGTAATTGACGAAAAAAGCCGCGGATTCCGCGGCTTTTTTATATAGTTATCTCAATTGTTTAATGTACACTTCTCGC
CTCTGAATGATAGGTAGCGG

Product: single-stranded DNA-binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MASRGVNKVILIGNLGQDPEVRYMPSGGAVANITIATSETWRDKATGEQKEKTEWHRVTLYGKLAEVAGEYLRKGSQVYI
EGQLQTRKWQDQSGQDRYSTEVVVQGYNGIMQMLGGRAQQGGMPAQGGMNVPAQQGSWGQPQQPAKQHQPMQQSAPQQYS
QPQYNEPPMDFDDDIPF

Sequences:

>Translated_177_residues
MASRGVNKVILIGNLGQDPEVRYMPSGGAVANITIATSETWRDKATGEQKEKTEWHRVTLYGKLAEVAGEYLRKGSQVYI
EGQLQTRKWQDQSGQDRYSTEVVVQGYNGIMQMLGGRAQQGGMPAQGGMNVPAQQGSWGQPQQPAKQHQPMQQSAPQQYS
QPQYNEPPMDFDDDIPF
>Mature_176_residues
ASRGVNKVILIGNLGQDPEVRYMPSGGAVANITIATSETWRDKATGEQKEKTEWHRVTLYGKLAEVAGEYLRKGSQVYIE
GQLQTRKWQDQSGQDRYSTEVVVQGYNGIMQMLGGRAQQGGMPAQGGMNVPAQQGSWGQPQQPAKQHQPMQQSAPQQYSQ
PQYNEPPMDFDDDIPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain

Homologues:

Organism=Homo sapiens, GI4507231, Length=109, Percent_Identity=32.1100917431193, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1790494, Length=185, Percent_Identity=73.5135135135135, Blast_Score=228, Evalue=1e-61,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SSB_VIBCH (Q9KUW2)

Other databases:

- EMBL:   AF079406
- EMBL:   AE003852
- PIR:   B82326
- RefSeq:   NP_230051.1
- ProteinModelPortal:   Q9KUW2
- SMR:   Q9KUW2
- GeneID:   2614994
- GenomeReviews:   AE003852_GR
- KEGG:   vch:VC0397
- TIGR:   VC_0397
- HOGENOM:   HBG755544
- OMA:   IMASRGV
- ProtClustDB:   PRK09010
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR10302
- TIGRFAMs:   TIGR00621

Pfam domain/function: PF00436 SSB; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 19673; Mature: 19542

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRGVNKVILIGNLGQDPEVRYMPSGGAVANITIATSETWRDKATGEQKEKTEWHRVTL
CCCCCCCEEEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEE
YGKLAEVAGEYLRKGSQVYIEGQLQTRKWQDQSGQDRYSTEVVVQGYNGIMQMLGGRAQQ
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHCCCCCC
GGMPAQGGMNVPAQQGSWGQPQQPAKQHQPMQQSAPQQYSQPQYNEPPMDFDDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHCCCHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASRGVNKVILIGNLGQDPEVRYMPSGGAVANITIATSETWRDKATGEQKEKTEWHRVTL
CCCCCCEEEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEE
YGKLAEVAGEYLRKGSQVYIEGQLQTRKWQDQSGQDRYSTEVVVQGYNGIMQMLGGRAQQ
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHCCCCCC
GGMPAQGGMNVPAQQGSWGQPQQPAKQHQPMQQSAPQQYSQPQYNEPPMDFDDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHCCCHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9973335; 10952301