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The map label for this gene is orn

Identifier: 227080553

GI number: 227080553

Start: 345884

End: 346429

Strand: Direct

Name: orn

Synonym: VCM66_0325

Alternate gene names: 227080553

Gene position: 345884-346429 (Clockwise)

Preceding gene: 227080546

Following gene: 227080555

Centisome position: 11.96

GC content: 45.6

Gene sequence:

>546_bases
ATGTCTTTCAGCGACCAGAATCTGATTTGGATTGATTTAGAGATGACGGGACTTGATCCTGAAATGCACAAAATCATTGA
GATGGCGACCATTGTTACTGACAGTGAGCTAAACATTTTAGCTGAAGGCCCAGTGATTGCGATTCATCAACCCGAATCCG
AACTCGCGAAAATGGATGAATGGTGTACCACAACGCACACCGCAAGTGGCTTGGTGGCGCGTGTACGTCAAAGCCAAGTG
AGTGAAGAAGAAGCCATAGATCAAACGCTCGCGTTTTTAAAGCAGTGGGTGCCGGAAGGCAAATCTCCGATTTGTGGCAA
CAGTATTGGTCAAGACAGACGTTTCCTTTACAAACACATGCCGCGTTTGGAAGCGTACTTCCATTATCGTTATATTGATG
TCAGCACCATCAAAGAGCTGACTCGCCGCTGGCAGCCTGAAGTGCTAAAAGAGTTCAGTAAAACAGGTAGCCATCTTGCT
TTGGATGATATTCGAGAGTCAATTGCTGAGCTTCAGTTCTATCGTAAGGCGGTATTCAAGATCTAA

Upstream 100 bases:

>100_bases
AGATATAAGGCGTATCAAATCTCAATTTGATACGTATCCTGTGGATCTGAATTTGGGTATAGTACCTCTTTTGTGAATAA
ACCCCTATAGGCGCACCATT

Downstream 100 bases:

>100_bases
TATCGGGTATTCAATGCTATAAAAAGAGCAATTGTTCGACATCTTGCATGCTTTTTCGGCAAGCGAAAAAAAAAAGAGTT
TTTTTCACGAGAAGCTCTTG

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MSFSDQNLIWIDLEMTGLDPEMHKIIEMATIVTDSELNILAEGPVIAIHQPESELAKMDEWCTTTHTASGLVARVRQSQV
SEEEAIDQTLAFLKQWVPEGKSPICGNSIGQDRRFLYKHMPRLEAYFHYRYIDVSTIKELTRRWQPEVLKEFSKTGSHLA
LDDIRESIAELQFYRKAVFKI

Sequences:

>Translated_181_residues
MSFSDQNLIWIDLEMTGLDPEMHKIIEMATIVTDSELNILAEGPVIAIHQPESELAKMDEWCTTTHTASGLVARVRQSQV
SEEEAIDQTLAFLKQWVPEGKSPICGNSIGQDRRFLYKHMPRLEAYFHYRYIDVSTIKELTRRWQPEVLKEFSKTGSHLA
LDDIRESIAELQFYRKAVFKI
>Mature_180_residues
SFSDQNLIWIDLEMTGLDPEMHKIIEMATIVTDSELNILAEGPVIAIHQPESELAKMDEWCTTTHTASGLVARVRQSQVS
EEEAIDQTLAFLKQWVPEGKSPICGNSIGQDRRFLYKHMPRLEAYFHYRYIDVSTIKELTRRWQPEVLKEFSKTGSHLAL
DDIRESIAELQFYRKAVFKI

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=176, Percent_Identity=52.2727272727273, Blast_Score=190, Evalue=5e-49,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=67.9558011049724, Blast_Score=269, Evalue=7e-74,
Organism=Caenorhabditis elegans, GI17557752, Length=175, Percent_Identity=50.8571428571429, Blast_Score=172, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6323088, Length=187, Percent_Identity=35.8288770053476, Blast_Score=116, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355135, Length=177, Percent_Identity=48.0225988700565, Blast_Score=185, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_VIBC3 (A5F3M7)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F3M7
- SMR:   A5F3M7
- STRING:   A5F3M7
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A2743
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- ProtClustDB:   PRK05359
- BioCyc:   VCHO345073:VC0395_A2743-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20929; Mature: 20798

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSDQNLIWIDLEMTGLDPEMHKIIEMATIVTDSELNILAEGPVIAIHQPESELAKMDE
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHHHHHHH
WCTTTHTASGLVARVRQSQVSEEEAIDQTLAFLKQWVPEGKSPICGNSIGQDRRFLYKHM
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
PRLEAYFHYRYIDVSTIKELTRRWQPEVLKEFSKTGSHLALDDIRESIAELQFYRKAVFK
HHHHHHHHHHEECHHHHHHHHHHCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHC
I
C
>Mature Secondary Structure 
SFSDQNLIWIDLEMTGLDPEMHKIIEMATIVTDSELNILAEGPVIAIHQPESELAKMDE
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHHHHHHH
WCTTTHTASGLVARVRQSQVSEEEAIDQTLAFLKQWVPEGKSPICGNSIGQDRRFLYKHM
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
PRLEAYFHYRYIDVSTIKELTRRWQPEVLKEFSKTGSHLALDDIRESIAELQFYRKAVFK
HHHHHHHHHHEECHHHHHHHHHHCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA