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The map label for this gene is glpG [H]

Identifier: 227080335

GI number: 227080335

Start: 97911

End: 98744

Strand: Reverse

Name: glpG [H]

Synonym: VCM66_0099

Alternate gene names: 227080335

Gene position: 98744-97911 (Counterclockwise)

Preceding gene: 227080336

Following gene: 227080334

Centisome position: 3.41

GC content: 48.32

Gene sequence:

>834_bases
ATGCATTTACTGACCACTTTTAACAATCCGCGTGCGGCACAAGCTTTTATCGATTACATGGCCGCCCACCACATTGAAAT
TCAGATGATGCCGGATGCAGGTGGTCAGTTCACTCTTTGGGTAATCCAAGATCAACACATCGAAACCGCACAAGCTGAAC
TCGCGCTGTTTTTAGAGAACCCTTATGCGGAAAAATACCAAGCCGCCTCATGGGAAGTCGCTGATCAAAAGCGCCCCCAA
TTTCATTACGCATCGCCCAATTTACTCAGTCTGATTAAAGCCAAAGCTGGAGTGTTTACGCTGTTTATTATGGCGCTATG
CATCATCATCTTTACTCTGCAAACGTTTGGTGCGGGAGATGAGGTGTTTAATGCATTACATTTTCCCGCTCTTGCTGGCC
AGCAATGGCAAATTTGGCGCTGGGTTAGTCATGCTTTACTGCACTTTTCCGTCATGCATATTGCCTTTAACTTACTCTGG
TGGTGGCAATTTGGGGGCGATCTTGAACAGCGCCTTGGCAGTGTCAGACTGATTAAGCTGTTTGTGGTGTCCGCGATTAT
CTCTGGAGCTGGTCAATACTGGGTTGAAGGCGCGAATTTTGGAGGCCTATCCGGTGTTGTCTATGCTTTGGCTGGGTATC
TGTGGATTCTTGGTCAGCGCGCCCCCCAACTGGGTTTATCCATTCCAAGATCCTTGATGGGCTTTATGCTGATCTGGTTA
GTGTTAGGTTATGTGCAGCCGTTTATGGCGATTGCCAATACCGCTCATTTAGCTGGCTTAATCAGCGGTGTCGTACTGGC
ATGGTTCGACAGCCAGCGCGACCAGCAAGCTTAA

Upstream 100 bases:

>100_bases
ATATCTGGTTAACCAAGGATTTGAAGAGGTGTATAGTGTCGATGGCGGCTTTGAAGCCTGGCATCGTGCCAATCTCCCCA
TCGAAGCGAGTTAAGGACTA

Downstream 100 bases:

>100_bases
GCATTTCCTCCTTTCTTGCGCCGCTTCTCTTTGAGTCGCGATCACGGTCAGCACGTATGCTGATCGTAAAACGGCTCACC
GACTTGTACTAATCACCCAA

Product: glpG protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MHLLTTFNNPRAAQAFIDYMAAHHIEIQMMPDAGGQFTLWVIQDQHIETAQAELALFLENPYAEKYQAASWEVADQKRPQ
FHYASPNLLSLIKAKAGVFTLFIMALCIIIFTLQTFGAGDEVFNALHFPALAGQQWQIWRWVSHALLHFSVMHIAFNLLW
WWQFGGDLEQRLGSVRLIKLFVVSAIISGAGQYWVEGANFGGLSGVVYALAGYLWILGQRAPQLGLSIPRSLMGFMLIWL
VLGYVQPFMAIANTAHLAGLISGVVLAWFDSQRDQQA

Sequences:

>Translated_277_residues
MHLLTTFNNPRAAQAFIDYMAAHHIEIQMMPDAGGQFTLWVIQDQHIETAQAELALFLENPYAEKYQAASWEVADQKRPQ
FHYASPNLLSLIKAKAGVFTLFIMALCIIIFTLQTFGAGDEVFNALHFPALAGQQWQIWRWVSHALLHFSVMHIAFNLLW
WWQFGGDLEQRLGSVRLIKLFVVSAIISGAGQYWVEGANFGGLSGVVYALAGYLWILGQRAPQLGLSIPRSLMGFMLIWL
VLGYVQPFMAIANTAHLAGLISGVVLAWFDSQRDQQA
>Mature_277_residues
MHLLTTFNNPRAAQAFIDYMAAHHIEIQMMPDAGGQFTLWVIQDQHIETAQAELALFLENPYAEKYQAASWEVADQKRPQ
FHYASPNLLSLIKAKAGVFTLFIMALCIIIFTLQTFGAGDEVFNALHFPALAGQQWQIWRWVSHALLHFSVMHIAFNLLW
WWQFGGDLEQRLGSVRLIKLFVVSAIISGAGQYWVEGANFGGLSGVVYALAGYLWILGQRAPQLGLSIPRSLMGFMLIWL
VLGYVQPFMAIANTAHLAGLISGVVLAWFDSQRDQQA

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=272, Percent_Identity=43.0147058823529, Blast_Score=215, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 31083; Mature: 31083

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLLTTFNNPRAAQAFIDYMAAHHIEIQMMPDAGGQFTLWVIQDQHIETAQAELALFLEN
CEEEECCCCCHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHEECC
PYAEKYQAASWEVADQKRPQFHYASPNLLSLIKAKAGVFTLFIMALCIIIFTLQTFGAGD
CCHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EVFNALHFPALAGQQWQIWRWVSHALLHFSVMHIAFNLLWWWQFGGDLEQRLGSVRLIKL
HHHHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHH
FVVSAIISGAGQYWVEGANFGGLSGVVYALAGYLWILGQRAPQLGLSIPRSLMGFMLIWL
HHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
VLGYVQPFMAIANTAHLAGLISGVVLAWFDSQRDQQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MHLLTTFNNPRAAQAFIDYMAAHHIEIQMMPDAGGQFTLWVIQDQHIETAQAELALFLEN
CEEEECCCCCHHHHHHHHHHHHHCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHEECC
PYAEKYQAASWEVADQKRPQFHYASPNLLSLIKAKAGVFTLFIMALCIIIFTLQTFGAGD
CCHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EVFNALHFPALAGQQWQIWRWVSHALLHFSVMHIAFNLLWWWQFGGDLEQRLGSVRLIKL
HHHHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHHH
FVVSAIISGAGQYWVEGANFGGLSGVVYALAGYLWILGQRAPQLGLSIPRSLMGFMLIWL
HHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
VLGYVQPFMAIANTAHLAGLISGVVLAWFDSQRDQQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA