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The map label for this gene is tcp [H]

Identifier: 227080334

GI number: 227080334

Start: 95557

End: 97536

Strand: Reverse

Name: tcp [H]

Synonym: VCM66_0098

Alternate gene names: 227080334

Gene position: 97536-95557 (Counterclockwise)

Preceding gene: 227080335

Following gene: 227080332

Centisome position: 3.37

GC content: 51.67

Gene sequence:

>1980_bases
ATGGGTTTATTGGCACGTCTTTTCTCTACAGCACCACATCATCCGACGCAACCAGCGGAGGTTAAGCCAGACCCGCTGAT
GCAATCTCCGGTAACCACCGAGACGACGGCATTACAGCCAGAACCACAGGTTGCGCCTTATCAAACTGACCTTGCGCTCA
CCACGCCAGAGTCAGACCTCACACCCCAAGTCAATCAAGCTTTTGTTCAGGTGATTCGTGAACATCTGGCACTGTTGGAA
TGTGAGCCCAACGGCACGATTTGCTATGCCAGTGATGCGTTTGCTCATCTCTGTCGGGTATCGGCTGAAGCGATGGTCGG
AGCGGATTTTGCGAACTTATGGCGCACTCATCAGCAGCCATCTGTGCAGCGCTTGCTGCAGGATGCTAAAAAAGGACACC
CTGTTTCTGCCGAATTACAGCTCAGCCGCTCGCAAGAGGCAATCTGGATAAAAGCGGATCTGTATCCCATCAAGGCGATA
AACGGTCAATTACAAAACGTGGTGGTACTGTTGCAAGATATCACTGCGGCCAAGCTGGAAAAAATTGACCGTAGTGGTCA
AATGAATGCGGTCAATCTCACCCAAGCCGTGATTGAATTTACGCTCGATGGCACCATTCTGACTGCAAATCAGAATTTTC
TGCAAACGGTGGGCTATCAGTTGGATGAGATCCAAGGGCGGCACCACAGCATGTTTGTTGATGAGCAGTATAAACAGAGT
CAAGAGTACCAACATTTCTGGCAGCGTTTGCGCTCCGGCGAATTCTTTGTCGACGAATACAAACGTTTCGGCAAAGGGGG
GAAAGAGATCTGGATCCAAGCCAGCTATAACCCGATTATGGACAGCGAGGGTAAACCGTATAAGGTTGTCAAATATGCCA
CCAACGTGACTCAGCGTAAGATGGTGGTCAATGAAGTCAAACGCGTCATGACGGCGCTCTCCAGCGGCGATCTCAGTGCA
CAACTCACGCATCCTTTTGAAGGTGAATTTGCTGAGCTCGGTGAGGTGATCAGTCAATTCATTGTCACATTGCGTCAAAT
CATTACTGACATCAACAGCGTCGCCGCGACCATCAAGCTAGCAGCGACGGAGATTTCCAATGGCAATACCGACCTCTCTA
GCCGAACCGAGCAACAAGCCTCCAATCTGGAGCAAACGGCCTCCAGCATGGAAGAGCTAAACAGCACGGTGCGACAAAAC
TCGGATAACGCCATGCAGGCGAACATCCTTGCGGGTAAAGCCACGGAAATCGCCGCCAGCGGTGGAGAACTGATTGAGCA
AGTGGTAGTGACTATGGCCTCGATTAACGAATCCGCGCAAAAGATCGCCGATATTATAGGTGTGATCGATGGTATTGCTT
TCCAAACCAATATTCTGGCACTCAATGCTGCGGTAGAGGCCGCTAGAGCCGGTGAACAAGGCCGCGGATTTTCCGTAGTC
GCCTCCGAAGTACGCTCACTCGCACAGCGCTCAGCCAATGCAGCGAAAGATATTAAGGCGCTCATCTCAGATTCCGTGAG
TAAAATCAGCAATGGGAATGAATTGGTGGATCGCTCCGGCAGCACCATGAAAGACATAGTCGTGTCGATCAAGCGAGTCC
ATGATTTGATGGCCGATATCGCCTCAGCGTCAGCCGAGCAGGCAACGGGGATCAATGAAGTGAACCAAGCAGTCAATCAG
ATGGATGAGATGACCCAACAAAATGCCGCACTCGTCGAAGAGGCAGCCGCGGCTTCAGAAAGCCTATTAGCACAGGCCGA
GCAGCTCTATGACCATGTCGCTATGTTCAGATTGCCAGATCAGGACACGAGCGCCCCATCACTGTTGAAAGCGGTCAATA
AGCGCCCGCAATCCGCACCAGTGACTCGACATCCGGCCAGCCACATCGCTAAAACGCCAGCAAAAATCACGGCCAAAGCC
AGCTCGAGGGCACAACCCGTTATGCAGGTCGCGCACGATGAAGAATGGGAGAGTTTTTGA

Upstream 100 bases:

>100_bases
CTCTGTGACTGGACGAAACGAACACGGCATCCAGCGTGACCGCTTCAAGTAGAAAAGGGAAATAAAAACATCAGTTGGTC
CCATCCAAGGAGAGCAGGTT

Downstream 100 bases:

>100_bases
GCCTGGGTTGGATGAAACCATGATGCAGCAGACATCGATACTCTGAGAGTAAAAAAGCGGCAACCGCCGCTTTTTTGTTT
ACTGACTCGTCGCTGAGCGA

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 659; Mature: 658

Protein sequence:

>659_residues
MGLLARLFSTAPHHPTQPAEVKPDPLMQSPVTTETTALQPEPQVAPYQTDLALTTPESDLTPQVNQAFVQVIREHLALLE
CEPNGTICYASDAFAHLCRVSAEAMVGADFANLWRTHQQPSVQRLLQDAKKGHPVSAELQLSRSQEAIWIKADLYPIKAI
NGQLQNVVVLLQDITAAKLEKIDRSGQMNAVNLTQAVIEFTLDGTILTANQNFLQTVGYQLDEIQGRHHSMFVDEQYKQS
QEYQHFWQRLRSGEFFVDEYKRFGKGGKEIWIQASYNPIMDSEGKPYKVVKYATNVTQRKMVVNEVKRVMTALSSGDLSA
QLTHPFEGEFAELGEVISQFIVTLRQIITDINSVAATIKLAATEISNGNTDLSSRTEQQASNLEQTASSMEELNSTVRQN
SDNAMQANILAGKATEIAASGGELIEQVVVTMASINESAQKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFSVV
ASEVRSLAQRSANAAKDIKALISDSVSKISNGNELVDRSGSTMKDIVVSIKRVHDLMADIASASAEQATGINEVNQAVNQ
MDEMTQQNAALVEEAAAASESLLAQAEQLYDHVAMFRLPDQDTSAPSLLKAVNKRPQSAPVTRHPASHIAKTPAKITAKA
SSRAQPVMQVAHDEEWESF

Sequences:

>Translated_659_residues
MGLLARLFSTAPHHPTQPAEVKPDPLMQSPVTTETTALQPEPQVAPYQTDLALTTPESDLTPQVNQAFVQVIREHLALLE
CEPNGTICYASDAFAHLCRVSAEAMVGADFANLWRTHQQPSVQRLLQDAKKGHPVSAELQLSRSQEAIWIKADLYPIKAI
NGQLQNVVVLLQDITAAKLEKIDRSGQMNAVNLTQAVIEFTLDGTILTANQNFLQTVGYQLDEIQGRHHSMFVDEQYKQS
QEYQHFWQRLRSGEFFVDEYKRFGKGGKEIWIQASYNPIMDSEGKPYKVVKYATNVTQRKMVVNEVKRVMTALSSGDLSA
QLTHPFEGEFAELGEVISQFIVTLRQIITDINSVAATIKLAATEISNGNTDLSSRTEQQASNLEQTASSMEELNSTVRQN
SDNAMQANILAGKATEIAASGGELIEQVVVTMASINESAQKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFSVV
ASEVRSLAQRSANAAKDIKALISDSVSKISNGNELVDRSGSTMKDIVVSIKRVHDLMADIASASAEQATGINEVNQAVNQ
MDEMTQQNAALVEEAAAASESLLAQAEQLYDHVAMFRLPDQDTSAPSLLKAVNKRPQSAPVTRHPASHIAKTPAKITAKA
SSRAQPVMQVAHDEEWESF
>Mature_658_residues
GLLARLFSTAPHHPTQPAEVKPDPLMQSPVTTETTALQPEPQVAPYQTDLALTTPESDLTPQVNQAFVQVIREHLALLEC
EPNGTICYASDAFAHLCRVSAEAMVGADFANLWRTHQQPSVQRLLQDAKKGHPVSAELQLSRSQEAIWIKADLYPIKAIN
GQLQNVVVLLQDITAAKLEKIDRSGQMNAVNLTQAVIEFTLDGTILTANQNFLQTVGYQLDEIQGRHHSMFVDEQYKQSQ
EYQHFWQRLRSGEFFVDEYKRFGKGGKEIWIQASYNPIMDSEGKPYKVVKYATNVTQRKMVVNEVKRVMTALSSGDLSAQ
LTHPFEGEFAELGEVISQFIVTLRQIITDINSVAATIKLAATEISNGNTDLSSRTEQQASNLEQTASSMEELNSTVRQNS
DNAMQANILAGKATEIAASGGELIEQVVVTMASINESAQKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFSVVA
SEVRSLAQRSANAAKDIKALISDSVSKISNGNELVDRSGSTMKDIVVSIKRVHDLMADIASASAEQATGINEVNQAVNQM
DEMTQQNAALVEEAAAASESLLAQAEQLYDHVAMFRLPDQDTSAPSLLKAVNKRPQSAPVTRHPASHIAKTPAKITAKAS
SRAQPVMQVAHDEEWESF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=365, Percent_Identity=47.945205479452, Blast_Score=285, Evalue=5e-78,
Organism=Escherichia coli, GI1788194, Length=309, Percent_Identity=50.8090614886731, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI2367378, Length=348, Percent_Identity=50.2873563218391, Blast_Score=272, Evalue=5e-74,
Organism=Escherichia coli, GI1787690, Length=320, Percent_Identity=48.125, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI1789453, Length=268, Percent_Identity=42.910447761194, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 71870; Mature: 71739

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS50885 HAMP ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLLARLFSTAPHHPTQPAEVKPDPLMQSPVTTETTALQPEPQVAPYQTDLALTTPESDL
CCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
TPQVNQAFVQVIREHLALLECEPNGTICYASDAFAHLCRVSAEAMVGADFANLWRTHQQP
CCHHHHHHHHHHHHHHHEEEECCCCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCH
SVQRLLQDAKKGHPVSAELQLSRSQEAIWIKADLYPIKAINGQLQNVVVLLQDITAAKLE
HHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCEEHHHHCCHHHHHHHHHHHHHHHHHH
KIDRSGQMNAVNLTQAVIEFTLDGTILTANQNFLQTVGYQLDEIQGRHHSMFVDEQYKQS
HHHCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHHCCHHHHHCCCHHCEECCHHHHHH
QEYQHFWQRLRSGEFFVDEYKRFGKGGKEIWIQASYNPIMDSEGKPYKVVKYATNVTQRK
HHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHH
MVVNEVKRVMTALSSGDLSAQLTHPFEGEFAELGEVISQFIVTLRQIITDINSVAATIKL
HHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATEISNGNTDLSSRTEQQASNLEQTASSMEELNSTVRQNSDNAMQANILAGKATEIAAS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHEECCCHHHHHCC
GGELIEQVVVTMASINESAQKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ASEVRSLAQRSANAAKDIKALISDSVSKISNGNELVDRSGSTMKDIVVSIKRVHDLMADI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
ASASAEQATGINEVNQAVNQMDEMTQQNAALVEEAAAASESLLAQAEQLYDHVAMFRLPD
HHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QDTSAPSLLKAVNKRPQSAPVTRHPASHIAKTPAKITAKASSRAQPVMQVAHDEEWESF
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHEECCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
GLLARLFSTAPHHPTQPAEVKPDPLMQSPVTTETTALQPEPQVAPYQTDLALTTPESDL
CHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
TPQVNQAFVQVIREHLALLECEPNGTICYASDAFAHLCRVSAEAMVGADFANLWRTHQQP
CCHHHHHHHHHHHHHHHEEEECCCCCEEECCHHHHHHHHHHHHHHHCCHHHHHHHHCCCH
SVQRLLQDAKKGHPVSAELQLSRSQEAIWIKADLYPIKAINGQLQNVVVLLQDITAAKLE
HHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCEEHHHHCCHHHHHHHHHHHHHHHHHH
KIDRSGQMNAVNLTQAVIEFTLDGTILTANQNFLQTVGYQLDEIQGRHHSMFVDEQYKQS
HHHCCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHHHCCHHHHHCCCHHCEECCHHHHHH
QEYQHFWQRLRSGEFFVDEYKRFGKGGKEIWIQASYNPIMDSEGKPYKVVKYATNVTQRK
HHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHH
MVVNEVKRVMTALSSGDLSAQLTHPFEGEFAELGEVISQFIVTLRQIITDINSVAATIKL
HHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AATEISNGNTDLSSRTEQQASNLEQTASSMEELNSTVRQNSDNAMQANILAGKATEIAAS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHEECCCHHHHHCC
GGELIEQVVVTMASINESAQKIADIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFSVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ASEVRSLAQRSANAAKDIKALISDSVSKISNGNELVDRSGSTMKDIVVSIKRVHDLMADI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
ASASAEQATGINEVNQAVNQMDEMTQQNAALVEEAAAASESLLAQAEQLYDHVAMFRLPD
HHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QDTSAPSLLKAVNKRPQSAPVTRHPASHIAKTPAKITAKASSRAQPVMQVAHDEEWESF
CCCCHHHHHHHHHCCCCCCCCCCCCHHHHHCCCHHHEECCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]