Click here to switch to the map view.

The map label for this gene is ykuT [H]

Identifier: 226951083

GI number: 226951083

Start: 4141113

End: 4141982

Strand: Reverse

Name: ykuT [H]

Synonym: CLM_4136

Alternate gene names: 226951083

Gene position: 4141982-4141113 (Counterclockwise)

Preceding gene: 226951084

Following gene: 226951082

Centisome position: 99.68

GC content: 25.17

Gene sequence:

>870_bases
ATGAAATCATCATTTAAATTTGATTTTGATTTATCAAAAGGCGGAATAAAAATAGGAGACTTCCTTATAAGTTCAGATTC
TGTATACCATTTTATATCAGTAGTTATTAATATAGCGATTATATGTGCAATAATGTATTTATCTATAAAAATAGGTAATA
AAATAATAAATAGATTTGTTAAAAAACAAAGCAATTTGAAATTTTCATTAGATGATAAAAAAGCTACAACTGTAGGAACT
ATATTAAATAGTATATTGAGATATACAGTTTATTTTGTAGGTATCTTCGCTATAATAGAAATTTTATTTGGAAGAATAGG
TTCTATATTTGCAGGACTTGGTGGTGCAGCTATAGGTTTAGGGGCTAAAGATCTTATAAAGGATGTAATAAGTGGATTTT
TTATATTATTTGAAGATCAATTTTCAGTAGGGGATTATATAACTGTAGAAGATAAATCTGGAATAGTTGATACCATAGAA
CTTAGAGTAACTAAATTAAAAGATTTCAATGGAGATGTTCATATAATACCTAATGGGTTAATAAATAAAGTAACTAATCA
CGCTAAAAATGATATGAGATTTAAGATAGAAATCAATATAGCTTACGAAGTAAATATAGAAGAAGCAATAAATAAAATTA
ATAAAGTATGTTTAGAGTATGCAAAAGAAAGAGAAGACATAGTAGTAGAACAACCAGCAGTGTATGGAATAACTTCATTA
GGGTCAAATGGAATAAGCATAGTTGTATATGGAAAAACAACTCCAATGAATCAATGGACTGCGGAAATTGAATTAAGAAA
GAAAATATTAATAGAACTAAAAAATGAAAATATAGAAATACCTTATAATAAATTTCAAATTATAAAATAA

Upstream 100 bases:

>100_bases
TTATGAAGATGTAAAAAAGATAATAGAAAGTAAAGAAATAAATATTAAAAATGTATATTTAAAGGAGGGTAAGGACTATC
AGTTAGTCATATAATGTTTT

Downstream 100 bases:

>100_bases
AAGGAGAGATTAGTTATGACTAAGACTTTTGATTTAGGAGATATAGTAGAAATGAAAAAATCTCATCCTTGCGGTAGTAA
TAGGTGGGAAATAATAAGGA

Product: mechanosensitive ion channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFVKKQSNLKFSLDDKKATTVGT
ILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGLGAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIE
LRVTKLKDFNGDVHIIPNGLINKVTNHAKNDMRFKIEINIAYEVNIEEAINKINKVCLEYAKEREDIVVEQPAVYGITSL
GSNGISIVVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK

Sequences:

>Translated_289_residues
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFVKKQSNLKFSLDDKKATTVGT
ILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGLGAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIE
LRVTKLKDFNGDVHIIPNGLINKVTNHAKNDMRFKIEINIAYEVNIEEAINKINKVCLEYAKEREDIVVEQPAVYGITSL
GSNGISIVVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK
>Mature_289_residues
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFVKKQSNLKFSLDDKKATTVGT
ILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGLGAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIE
LRVTKLKDFNGDVHIIPNGLINKVTNHAKNDMRFKIEINIAYEVNIEEAINKINKVCLEYAKEREDIVVEQPAVYGITSL
GSNGISIVVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=179, Percent_Identity=25.6983240223464, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786670, Length=216, Percent_Identity=26.3888888888889, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787591, Length=217, Percent_Identity=27.1889400921659, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI2367355, Length=223, Percent_Identity=26.0089686098655, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789291, Length=278, Percent_Identity=21.9424460431655, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 32351; Mature: 32351

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFV
CCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQSNLKFSLDDKKATTVGTILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGL
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
GAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIELRVTKLKDFNGDVHIIPNGL
CHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECCHH
INKVTNHAKNDMRFKIEINIAYEVNIEEAINKINKVCLEYAKEREDIVVEQPAVYGITSL
HHHHHHCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCC
GSNGISIVVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK
CCCCEEEEEEECCCCCCHHHHHHHHHHHEEEEECCCCEECCCHHEEEEC
>Mature Secondary Structure
MKSSFKFDFDLSKGGIKIGDFLISSDSVYHFISVVINIAIICAIMYLSIKIGNKIINRFV
CCCCEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQSNLKFSLDDKKATTVGTILNSILRYTVYFVGIFAIIEILFGRIGSIFAGLGGAAIGL
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
GAKDLIKDVISGFFILFEDQFSVGDYITVEDKSGIVDTIELRVTKLKDFNGDVHIIPNGL
CHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCCCEEEEEEEEEEEECCCCCEEEECCHH
INKVTNHAKNDMRFKIEINIAYEVNIEEAINKINKVCLEYAKEREDIVVEQPAVYGITSL
HHHHHHCCCCCEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEECCC
GSNGISIVVYGKTTPMNQWTAEIELRKKILIELKNENIEIPYNKFQIIK
CCCCEEEEEEECCCCCCHHHHHHHHHHHEEEEECCCCEECCCHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]