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The map label for this gene is trxB [C]

Identifier: 226950885

GI number: 226950885

Start: 3941506

End: 3942369

Strand: Reverse

Name: trxB [C]

Synonym: CLM_3900

Alternate gene names: 226950885

Gene position: 3942369-3941506 (Counterclockwise)

Preceding gene: 226950886

Following gene: 226950883

Centisome position: 94.88

GC content: 30.44

Gene sequence:

>864_bases
ATGGGGAAAAGATATGATATAGCTATAATAGGTAGCGGACCTGCAGGGTTGGAAGCAGCCATAAATGCTAAAGTAAGAAA
TAAGGATATAATAATATTTGGTAATAAGGAGTTAAGTTCAAAACTTGTGAAGGCTCCTAAAATAAATAATTATCTTGGTT
TTTATGATATTTCAGGTAATGAGCTAAAAGATAAATTTATAGATCATATAGATAAGATGGGAATAGAAATAACTTTTGAG
AGAATAAATAATGTTTATGCTATGGGAGAATATTTTGCTCTAATGGTTAATGAAAAAATGTATGAAGCTAAAACAGTTAT
ATTAGCTACTGGAGTAGAGTATGGGAAAGCATTAAAAGGTGAAGAGGAATTTTTAGGGAAAGGTGTAGGATATTGTGCTA
CTTGTGATGCACCACTTTATAAAAATAAGACAGTTGCCATAATAGGATATAATAAAGAAGCTGAGGAAGAAGCTAATTTT
GTAAGCGAATTAGCATCAAAACTTTATTATATTCCTATGTACAGATCAGATTATGAATTAAGTGAAAAAGTGGAAGTTAT
TAATGATAAACCTATAGAAATAGTAGGAAAACAACATGTGGAAAAATTAATTCTTAAAGATTCAGAAATAGAAGCAGATG
GTATTTTTGTTTTAAAAGATAGTATATCTCCCTCACAATTAGTACCGGGCTTAGAAATGGAAGATGAACATATAAAGGTT
GATAGGAAAATGAAAACTAATATATCAGGATGCTTTGCTGCAGGGGATTGTACTGGTAAACCATATCAATATATAAAATC
TGCAGGAGAAGGTCAAATTGCAGCATTAAGTGCAGTTTCTTATTTAGATAAACAGAGTTCTTAG

Upstream 100 bases:

>100_bases
AAGCTATAAAATCAGCAGTAGAAAAGCATATTTAATATAAAATAAATTGAGAATAGCATTAATGTTATTCTCAATTTTAC
ATTTTTTAGGAGGAGATATT

Downstream 100 bases:

>100_bases
CTTTAGAAGGAGCTTTTACTCCCACTAAAGCTTATTAACAGAATTCTTAGGAGTTCTACTCCTTAGAAGTAGTTATCCTT
TAGGGGAAATCGTTATCCAG

Product: oxidoreductase, pyridine nucleotide-disulfide family

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MGKRYDIAIIGSGPAGLEAAINAKVRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGNELKDKFIDHIDKMGIEITFE
RINNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKGEEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANF
VSELASKLYYIPMYRSDYELSEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPSQLVPGLEMEDEHIKV
DRKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS

Sequences:

>Translated_287_residues
MGKRYDIAIIGSGPAGLEAAINAKVRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGNELKDKFIDHIDKMGIEITFE
RINNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKGEEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANF
VSELASKLYYIPMYRSDYELSEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPSQLVPGLEMEDEHIKV
DRKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS
>Mature_286_residues
GKRYDIAIIGSGPAGLEAAINAKVRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGNELKDKFIDHIDKMGIEITFER
INNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKGEEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANFV
SELASKLYYIPMYRSDYELSEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPSQLVPGLEMEDEHIKVD
RKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=32.9073482428115, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI87081763, Length=261, Percent_Identity=29.1187739463602, Blast_Score=98, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6320560, Length=312, Percent_Identity=33.0128205128205, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6321898, Length=316, Percent_Identity=31.3291139240506, Blast_Score=105, Evalue=9e-24,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 31797; Mature: 31666

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKRYDIAIIGSGPAGLEAAINAKVRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGN
CCCEEEEEEEECCCCCCEEEEECEECCCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCC
ELKDKFIDHIDKMGIEITFERINNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKG
HHHHHHHHHHHHCCCEEEEHHHCCCHHHHHEEEEEECCHHHHCEEEEEEECCHHHHHCCC
EEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANFVSELASKLYYIPMYRSDYEL
CHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCCCCH
SEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPSQLVPGLEMEDEHIKV
HHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCEEEEECCCCHHHCCCCCCCCCCCEEE
DRKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS
CCHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
GKRYDIAIIGSGPAGLEAAINAKVRNKDIIIFGNKELSSKLVKAPKINNYLGFYDISGN
CCEEEEEEEECCCCCCEEEEECEECCCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCC
ELKDKFIDHIDKMGIEITFERINNVYAMGEYFALMVNEKMYEAKTVILATGVEYGKALKG
HHHHHHHHHHHHCCCEEEEHHHCCCHHHHHEEEEEECCHHHHCEEEEEEECCHHHHHCCC
EEEFLGKGVGYCATCDAPLYKNKTVAIIGYNKEAEEEANFVSELASKLYYIPMYRSDYEL
CHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEEECCCCCH
SEKVEVINDKPIEIVGKQHVEKLILKDSEIEADGIFVLKDSISPSQLVPGLEMEDEHIKV
HHHHHHCCCCCCEEECHHHHHHHHHCCCCCCCCCEEEEECCCCHHHCCCCCCCCCCCEEE
DRKMKTNISGCFAAGDCTGKPYQYIKSAGEGQIAALSAVSYLDKQSS
CCHHHCCCCEEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]