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The map label for this gene is gcp [H]

Identifier: 226950738

GI number: 226950738

Start: 3773974

End: 3774996

Strand: Reverse

Name: gcp [H]

Synonym: CLM_3747

Alternate gene names: 226950738

Gene position: 3774996-3773974 (Counterclockwise)

Preceding gene: 226950741

Following gene: 226950737

Centisome position: 90.85

GC content: 34.21

Gene sequence:

>1023_bases
ATGAAAGAAAGCATAAATATTTTAGCTATAGAAAGTAGCTGTGATGAAACTTCAGCGGCAGTAGTTGTTAATGGTAGAGA
AGTTTTATCTAATATAATAGCATCACAAATAAGCACCCATGAAAAATTTGGAGGTGTAGTGCCAGAAGTTGCTTCAAGAA
AGCATATAGAGGTTATAAGTGCAGTAGTACAAGAAGCTTTAGATGAAGCAAATTTTACTTTAGATGATATAGATGCTATA
GGTGTAACCTATGGACCAGGGTTAGTAGGAGCTCTACTTGTGGGATTACAATATGCGAAAGGGCTAGCCTTTGCAACAGG
GAAGCCTCTTATAGGAGTAAATCATATAGAAGGTCATATAAGTGCAAATTTTATAGAATATAAAGACTTAAAGCCACCTT
TTATGTGTTTAGTAGTATCAGGAGGACATACTTTTATAGTTTATATGAAAGATTATGGTGAATTTGAAGTGTTAGGTGAA
ACTAGGGATGATGCAGCGGGAGAAGCTTTTGATAAAGTGGCCAGAGCCATAGGGTTAGGCTATCCTGGAGGACCTAAAAT
AGATAAAATATCAAAGGAAGGAAACGAAGAGGCTATAAAATTTCCAAGAGCAAATTTTCATAATGATACTTTAGATTTTT
CCTTTAGCGGAATAAAATCAGCAGTATTAAACTATTTAAATAAGAAGGAAATGAAGGGAGAAGAAATAAATAAAGCAGAT
GTGGCAGCATCTTTTCAAAAGTCTGTGGTAGATGTTCTTGTAGACAATACTATAAAGGCTTGTATGAGTAAAAAAGTAGA
TAAAATAGCAGTAGCAGGAGGAGTAGCATCTAATTCCTGCCTAAGAGAGACTTTAGTAAGAGAGTGTAAGAAAAAAGGAA
TAGAAGTGTTAATACCACCTTTTATATTGTGTACAGATAATGCAGCTATGATAGGAAGCGCAGCTTATTTTGAATATATT
AAGGGAAGAAGTACTTCTTTAGATATAAATGCTGTACCAAATTTGAAACTTGGAGAAAGATAG

Upstream 100 bases:

>100_bases
ATATATAAATTCAATAAAGTATAATGTAATTTAGATTTATAAAAGAATAATAAATTACATAGTTAATATATATTTAATTA
CATAAAAAGGAGTAGGAAAT

Downstream 100 bases:

>100_bases
AAACTATTAAACTTTCAATATAAGTAAGATTTTATATAATAATAAAGACTTTCTTTTATAAATAAATGATAGAATAAAAT
AAAAATCTACTATTATTTAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVISAVVQEALDEANFTLDDIDAI
GVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHISANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGE
TRDDAAGEAFDKVARAIGLGYPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPPFILCTDNAAMIGSAAYFEYI
KGRSTSLDINAVPNLKLGER

Sequences:

>Translated_340_residues
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVISAVVQEALDEANFTLDDIDAI
GVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHISANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGE
TRDDAAGEAFDKVARAIGLGYPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPPFILCTDNAAMIGSAAYFEYI
KGRSTSLDINAVPNLKLGER
>Mature_340_residues
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVISAVVQEALDEANFTLDDIDAI
GVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHISANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGE
TRDDAAGEAFDKVARAIGLGYPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPPFILCTDNAAMIGSAAYFEYI
KGRSTSLDINAVPNLKLGER

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=331, Percent_Identity=34.1389728096677, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI8923380, Length=328, Percent_Identity=30.1829268292683, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1789445, Length=335, Percent_Identity=41.1940298507463, Blast_Score=265, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17557464, Length=331, Percent_Identity=28.7009063444109, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71995670, Length=318, Percent_Identity=29.559748427673, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6320099, Length=371, Percent_Identity=33.1536388140162, Blast_Score=145, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6322891, Length=318, Percent_Identity=28.9308176100629, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI20129063, Length=354, Percent_Identity=30.225988700565, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI21357207, Length=320, Percent_Identity=30.625, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36510; Mature: 36510

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVIS
CCCCEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHH
AVVQEALDEANFTLDDIDAIGVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHI
HHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCE
SANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGETRDDAAGEAFDKVARAIGLG
EECEEEECCCCCCEEEEEEECCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCC
YPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
CCCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHH
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPP
HHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHCCCEEEECC
FILCTDNAAMIGSAAYFEYIKGRSTSLDINAVPNLKLGER
EEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MKESINILAIESSCDETSAAVVVNGREVLSNIIASQISTHEKFGGVVPEVASRKHIEVIS
CCCCEEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHH
AVVQEALDEANFTLDDIDAIGVTYGPGLVGALLVGLQYAKGLAFATGKPLIGVNHIEGHI
HHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCE
SANFIEYKDLKPPFMCLVVSGGHTFIVYMKDYGEFEVLGETRDDAAGEAFDKVARAIGLG
EECEEEECCCCCCEEEEEEECCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHCCC
YPGGPKIDKISKEGNEEAIKFPRANFHNDTLDFSFSGIKSAVLNYLNKKEMKGEEINKAD
CCCCCCCHHHHCCCCHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCHHH
VAASFQKSVVDVLVDNTIKACMSKKVDKIAVAGGVASNSCLRETLVRECKKKGIEVLIPP
HHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHCCCEEEECC
FILCTDNAAMIGSAAYFEYIKGRSTSLDINAVPNLKLGER
EEEECCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA