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The map label for this gene is pyc [H]

Identifier: 226950737

GI number: 226950737

Start: 3770080

End: 3773514

Strand: Reverse

Name: pyc [H]

Synonym: CLM_3746

Alternate gene names: 226950737

Gene position: 3773514-3770080 (Counterclockwise)

Preceding gene: 226950738

Following gene: 226950736

Centisome position: 90.81

GC content: 32.29

Gene sequence:

>3435_bases
ATGAACAAGTTTAAAAGAGTATTAGTGGCAAATAGAGGTGAAATCGCAATAAGAGTGTTTAGAGCATGTCATGAATTAGG
CATTAGAACTGTTGCGATATATTCAGAAGAAGATAAATTCTCACTATTTAGAACCAAGGCAGATGAAGCATATCTTATAG
GAAAAAATAAAGGTCCTATAGATGCTTATTTGAATATCGAAGAAATAATACAATTGGCTTTGAAAAAAGGGGTAGATGCT
ATACATCCAGGTTATGGCTTCTTGGCAGAGAATTCTGAATTTGCAAGAAAATGTAGAGAAGCAGGGATAGAGTTTATAGG
GCCTACAGCGGAAATGATGGAAAAGCTAGGAGATAAAATAAAGTCTAAAATAGTTGCAGAAAAAGCAGGGGTACCTACTA
TACCTGGAGTTCAAAAACCAATTAAATCAGAGAAAGAAGCTTTAGAATTTGCAAGATACTGTGGATATCCAATAATGCTC
AAGGCAGCTGCTGGTGGTGGCGGTAGAGGGATGAGAATAGTTAGAACAGAAGAAGAATTAATATCTTCCTTTAAAAGTGC
AAAAAATGAAGCTAAAAAGGCTTTTGGTATAGATGATATATTTATAGAAAAATATTTAGAAAATCCTAAACATATAGAAG
TTCAAATATTAGGAGATAAGCATGGAGATATAGTGCATCTATATGAAAGGGACTGTTCTATACAAAGAAGACATCAAAAG
GTTATAGAATTTACACCAGCTTTTGCCCTACCAAAGAAAAAGAGAGAAGAAATATGTAATGATGCTTTAAAAATAGCTAA
AACTGTAGGGTATAGAAGTGCAGGTACATTAGAATTTTTAGTAGATACTACAGGAAATCATTATTTTATAGAAATGAATC
CAAGAATACAGGTAGAACATACTGTTACAGAAATGATTACAGGAATTGATATTGTTCAAAGTCAAATTTTAATAGCAGAG
GGATACAAATTAGATTCAGAAGAAGTAGGTATAAAATCTCAAGAATCCATACAAACAAGAGGATATGCTATTCAGTGTAG
GGTAACTACAGAAGATCCATCTAATAATTTTGCACCAGATACAGGGAAAATAGAAGATTATAGAACAGGTTCAGGATTTG
GTATTAGATTAGACGGTGGGAATGGTTTTACAGGTTCTGTTATAAGCCCATATTATGATAGTTTATTAGTTAAAACTACA
TCCTGGTCTAGAACATTTAACGATGCTATAAGAAAGTCCATAAGAGCTATAAAAGAATTTAAAATAGATGGTGTTAAAAC
TAACATAGGATTTTTAATAAATGTTTTAAATCATGAACAATTTAGAAAAGGACAATGTGATACTAATTTTATAGAAAAGA
ATCCAGAATTATTTGATATAACATCAAAAACCGATGATGAAGTTAGAATATTAAAATTCATAGGTGAAAAGGTAGTAAAT
GAAACCCATGGTATAAAGAAAGATTTTGATGTGCCTACAATACCAATAGTAGATGAAGGATTAAGTTTAAAAGGAACTAA
ACAAATATTAGACGAAAAAGGTCCAGAGGGGTTAGTGAGTTGGATAAAAACTCAAAATAAGCTTCTTTTGACAGACACAA
CTATGAGAGATGCTCATCAATCTCTTATGGCCACAAGAATGAGAAGTGTAGATATGTTTAAAATAGCTAAGGCTCAATCA
GTGCTTGGAAAAGATTTATTTTCCATGGAAATGTGGGGAGGAGCAACCTTTGATGTAGCTTATAGATTTTTAAAAGAATC
TCCTTGGACTAGACTGGAAGAGCTAAGAAAATCTATACCGAATGTATTGTTTCAAATGCTAATAAGAGGGGCTAACGCGG
TTGGCTATAAAAATTATCCAGACAATGTTATAAGAAAATTTATAAAGCAGTCTGCAGATTCAGGTATAGATGTATTTAGA
ATATTTGATTCCTTAAACTGGTTAAAGGGAATGGAAGTAGCCACAGATGAGGTTTTAAAACAAAATAAAGTAGCAGAAAC
TTGTATGTGTTATACAGGAGATATATTAGAAGGATATAGAGATAAATATAGCTTGCAATATTATGTGGATTTAGCAAAAG
ATATAGAAAAAACAGGAGCACATATACTTGGAATAAAAGATATGTCAGCTTTATTAAAACCATATGCTGCAGTTAAGCTT
ATAAAGGCATTAAAAAATGAAATATCTATCCCAATACATCTTCATACTCATGATACTACAGGTAATGGTGTGGCTACAGT
ACTTATGGCAGCCCATGCAGGAGTTGATATTGTAGATACTGCGTTTAATAGTATGTCAGGCCTTACAAGTCAACCAGCCT
TAAATTCCATAGTAGCAGCATTAGAAAACACAGATAGGGAAACAGGACTAGATTTAACAGATATGCAGAAATTATCAGAC
TATTGGAGTGCTGTCAGACCGGTATATAGTCAACTCGAGTCAGGATTAAAATCAGGTTCTGCAGAAATATATAAATACGA
AATACCTGGAGGACAATATTCTAATTTAAAACCACAGGTAGAAAGCTTTGGATTAGGTCATAAATTTGAAGAAGTAAAAG
AAATGTATAAAAAAGTTAATGAAATGCTTGGTGATATTATAAAGGTTACTCCATCTTCAAAGGTGGTTGGAGACTTGGCT
ATCTTTATGGTAAAAAATGATCTAACACCTGAAAATATATATGAAAAAGCTGAAAAAATGGCTTTTCCAGATTCAGCTGT
ATCATATTTTAAAGGAATGATGGGTCAACCAATGGGTGGTTTCCCAGAAAAATTGCAGAAGTTAGTTTTAAAAGGGGAAG
ACCCTATAACTTGTAGACCAGGAGAGATGTTGCCTCCAGAAGATTTTGAAAAAATAAGAGAACATTTAAAGGAAAAGCAT
GATTTAGATGCAACAGAAAATGATATTATAAGTTATGCATTATATCCAGAGGTTTTTGATAAGTATTTAGACTTTTTAAA
GGAATACGGGGATTTAAGTCATATGGGTAGTGATGTATTCTTCCATGGATTATATGAAGGAGAAACAGCTGAAATAGAGC
TACAAGAAGGAAAAACATTTATAGTTCAATTATCTGAAATAGGAAAAGTAGATTCAGAGGGGAATAGAGCAGTAGTTTTT
GAAATAAATGGGAATAGAAGAGAAATAAGAATAAAAGATAAATCTAGTTTAATGGCGCAAAATATAACTTCTAATAGCAC
AAAGATGGCAGATCCTGCAAATAAAAAACATATAGGATCTAGTATACCAGGTACAGTAATAAAAGTTTTAGTAAATAAGG
GAGATGAAATAAAAGAAGGAGATAGCTTGATTGTAATAGAAGCTATGAAAATGGAAACTAATATAGTGGCTAGTTTGTCA
GGGGTAGTAGGAAGTTTGTTAGTAAAAGAAGGAGATCAAGTTAAGTCAGGGCAACTACTTTTAGAATTAGAATAA

Upstream 100 bases:

>100_bases
AAAAATTTTATAAATTATATATAATGTAAAGGTATATCTATAATTTAGAAAGTAATGCAGTTAAAAATAAGGCACAATAT
TTACAAAAAGGGGGATAATA

Downstream 100 bases:

>100_bases
TTAGATAAACAGAGTTCTTGGCTTCAGATGGAGTTTTTACTCCCCCTGAAGCTTAGAAATCGTTATCTAGGGACGTAGCC
GCTCTTTACTCTCACTTTGA

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1144; Mature: 1144

Protein sequence:

>1144_residues
MNKFKRVLVANRGEIAIRVFRACHELGIRTVAIYSEEDKFSLFRTKADEAYLIGKNKGPIDAYLNIEEIIQLALKKGVDA
IHPGYGFLAENSEFARKCREAGIEFIGPTAEMMEKLGDKIKSKIVAEKAGVPTIPGVQKPIKSEKEALEFARYCGYPIML
KAAAGGGGRGMRIVRTEEELISSFKSAKNEAKKAFGIDDIFIEKYLENPKHIEVQILGDKHGDIVHLYERDCSIQRRHQK
VIEFTPAFALPKKKREEICNDALKIAKTVGYRSAGTLEFLVDTTGNHYFIEMNPRIQVEHTVTEMITGIDIVQSQILIAE
GYKLDSEEVGIKSQESIQTRGYAIQCRVTTEDPSNNFAPDTGKIEDYRTGSGFGIRLDGGNGFTGSVISPYYDSLLVKTT
SWSRTFNDAIRKSIRAIKEFKIDGVKTNIGFLINVLNHEQFRKGQCDTNFIEKNPELFDITSKTDDEVRILKFIGEKVVN
ETHGIKKDFDVPTIPIVDEGLSLKGTKQILDEKGPEGLVSWIKTQNKLLLTDTTMRDAHQSLMATRMRSVDMFKIAKAQS
VLGKDLFSMEMWGGATFDVAYRFLKESPWTRLEELRKSIPNVLFQMLIRGANAVGYKNYPDNVIRKFIKQSADSGIDVFR
IFDSLNWLKGMEVATDEVLKQNKVAETCMCYTGDILEGYRDKYSLQYYVDLAKDIEKTGAHILGIKDMSALLKPYAAVKL
IKALKNEISIPIHLHTHDTTGNGVATVLMAAHAGVDIVDTAFNSMSGLTSQPALNSIVAALENTDRETGLDLTDMQKLSD
YWSAVRPVYSQLESGLKSGSAEIYKYEIPGGQYSNLKPQVESFGLGHKFEEVKEMYKKVNEMLGDIIKVTPSSKVVGDLA
IFMVKNDLTPENIYEKAEKMAFPDSAVSYFKGMMGQPMGGFPEKLQKLVLKGEDPITCRPGEMLPPEDFEKIREHLKEKH
DLDATENDIISYALYPEVFDKYLDFLKEYGDLSHMGSDVFFHGLYEGETAEIELQEGKTFIVQLSEIGKVDSEGNRAVVF
EINGNRREIRIKDKSSLMAQNITSNSTKMADPANKKHIGSSIPGTVIKVLVNKGDEIKEGDSLIVIEAMKMETNIVASLS
GVVGSLLVKEGDQVKSGQLLLELE

Sequences:

>Translated_1144_residues
MNKFKRVLVANRGEIAIRVFRACHELGIRTVAIYSEEDKFSLFRTKADEAYLIGKNKGPIDAYLNIEEIIQLALKKGVDA
IHPGYGFLAENSEFARKCREAGIEFIGPTAEMMEKLGDKIKSKIVAEKAGVPTIPGVQKPIKSEKEALEFARYCGYPIML
KAAAGGGGRGMRIVRTEEELISSFKSAKNEAKKAFGIDDIFIEKYLENPKHIEVQILGDKHGDIVHLYERDCSIQRRHQK
VIEFTPAFALPKKKREEICNDALKIAKTVGYRSAGTLEFLVDTTGNHYFIEMNPRIQVEHTVTEMITGIDIVQSQILIAE
GYKLDSEEVGIKSQESIQTRGYAIQCRVTTEDPSNNFAPDTGKIEDYRTGSGFGIRLDGGNGFTGSVISPYYDSLLVKTT
SWSRTFNDAIRKSIRAIKEFKIDGVKTNIGFLINVLNHEQFRKGQCDTNFIEKNPELFDITSKTDDEVRILKFIGEKVVN
ETHGIKKDFDVPTIPIVDEGLSLKGTKQILDEKGPEGLVSWIKTQNKLLLTDTTMRDAHQSLMATRMRSVDMFKIAKAQS
VLGKDLFSMEMWGGATFDVAYRFLKESPWTRLEELRKSIPNVLFQMLIRGANAVGYKNYPDNVIRKFIKQSADSGIDVFR
IFDSLNWLKGMEVATDEVLKQNKVAETCMCYTGDILEGYRDKYSLQYYVDLAKDIEKTGAHILGIKDMSALLKPYAAVKL
IKALKNEISIPIHLHTHDTTGNGVATVLMAAHAGVDIVDTAFNSMSGLTSQPALNSIVAALENTDRETGLDLTDMQKLSD
YWSAVRPVYSQLESGLKSGSAEIYKYEIPGGQYSNLKPQVESFGLGHKFEEVKEMYKKVNEMLGDIIKVTPSSKVVGDLA
IFMVKNDLTPENIYEKAEKMAFPDSAVSYFKGMMGQPMGGFPEKLQKLVLKGEDPITCRPGEMLPPEDFEKIREHLKEKH
DLDATENDIISYALYPEVFDKYLDFLKEYGDLSHMGSDVFFHGLYEGETAEIELQEGKTFIVQLSEIGKVDSEGNRAVVF
EINGNRREIRIKDKSSLMAQNITSNSTKMADPANKKHIGSSIPGTVIKVLVNKGDEIKEGDSLIVIEAMKMETNIVASLS
GVVGSLLVKEGDQVKSGQLLLELE
>Mature_1144_residues
MNKFKRVLVANRGEIAIRVFRACHELGIRTVAIYSEEDKFSLFRTKADEAYLIGKNKGPIDAYLNIEEIIQLALKKGVDA
IHPGYGFLAENSEFARKCREAGIEFIGPTAEMMEKLGDKIKSKIVAEKAGVPTIPGVQKPIKSEKEALEFARYCGYPIML
KAAAGGGGRGMRIVRTEEELISSFKSAKNEAKKAFGIDDIFIEKYLENPKHIEVQILGDKHGDIVHLYERDCSIQRRHQK
VIEFTPAFALPKKKREEICNDALKIAKTVGYRSAGTLEFLVDTTGNHYFIEMNPRIQVEHTVTEMITGIDIVQSQILIAE
GYKLDSEEVGIKSQESIQTRGYAIQCRVTTEDPSNNFAPDTGKIEDYRTGSGFGIRLDGGNGFTGSVISPYYDSLLVKTT
SWSRTFNDAIRKSIRAIKEFKIDGVKTNIGFLINVLNHEQFRKGQCDTNFIEKNPELFDITSKTDDEVRILKFIGEKVVN
ETHGIKKDFDVPTIPIVDEGLSLKGTKQILDEKGPEGLVSWIKTQNKLLLTDTTMRDAHQSLMATRMRSVDMFKIAKAQS
VLGKDLFSMEMWGGATFDVAYRFLKESPWTRLEELRKSIPNVLFQMLIRGANAVGYKNYPDNVIRKFIKQSADSGIDVFR
IFDSLNWLKGMEVATDEVLKQNKVAETCMCYTGDILEGYRDKYSLQYYVDLAKDIEKTGAHILGIKDMSALLKPYAAVKL
IKALKNEISIPIHLHTHDTTGNGVATVLMAAHAGVDIVDTAFNSMSGLTSQPALNSIVAALENTDRETGLDLTDMQKLSD
YWSAVRPVYSQLESGLKSGSAEIYKYEIPGGQYSNLKPQVESFGLGHKFEEVKEMYKKVNEMLGDIIKVTPSSKVVGDLA
IFMVKNDLTPENIYEKAEKMAFPDSAVSYFKGMMGQPMGGFPEKLQKLVLKGEDPITCRPGEMLPPEDFEKIREHLKEKH
DLDATENDIISYALYPEVFDKYLDFLKEYGDLSHMGSDVFFHGLYEGETAEIELQEGKTFIVQLSEIGKVDSEGNRAVVF
EINGNRREIRIKDKSSLMAQNITSNSTKMADPANKKHIGSSIPGTVIKVLVNKGDEIKEGDSLIVIEAMKMETNIVASLS
GVVGSLLVKEGDQVKSGQLLLELE

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1151, Percent_Identity=48.5664639443962, Blast_Score=1112, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1151, Percent_Identity=48.5664639443962, Blast_Score=1112, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1151, Percent_Identity=48.5664639443962, Blast_Score=1112, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=459, Percent_Identity=44.0087145969499, Blast_Score=393, Evalue=1e-109,
Organism=Homo sapiens, GI189095269, Length=454, Percent_Identity=44.7136563876652, Blast_Score=379, Evalue=1e-104,
Organism=Homo sapiens, GI65506442, Length=451, Percent_Identity=45.0110864745011, Blast_Score=378, Evalue=1e-104,
Organism=Homo sapiens, GI295821183, Length=451, Percent_Identity=45.0110864745011, Blast_Score=378, Evalue=1e-104,
Organism=Homo sapiens, GI134142062, Length=514, Percent_Identity=31.7120622568093, Blast_Score=253, Evalue=1e-66,
Organism=Homo sapiens, GI38679960, Length=514, Percent_Identity=31.3229571984436, Blast_Score=251, Evalue=2e-66,
Organism=Homo sapiens, GI38679977, Length=514, Percent_Identity=31.3229571984436, Blast_Score=251, Evalue=3e-66,
Organism=Homo sapiens, GI38679967, Length=514, Percent_Identity=31.3229571984436, Blast_Score=251, Evalue=3e-66,
Organism=Homo sapiens, GI38679974, Length=514, Percent_Identity=31.3229571984436, Blast_Score=251, Evalue=3e-66,
Organism=Homo sapiens, GI38679971, Length=514, Percent_Identity=31.3229571984436, Blast_Score=251, Evalue=3e-66,
Organism=Escherichia coli, GI1789654, Length=449, Percent_Identity=44.543429844098, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI1786216, Length=352, Percent_Identity=24.7159090909091, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562816, Length=1153, Percent_Identity=50.2168256721596, Blast_Score=1152, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=475, Percent_Identity=43.578947368421, Blast_Score=370, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17567343, Length=468, Percent_Identity=42.0940170940171, Blast_Score=354, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI133931226, Length=494, Percent_Identity=33.1983805668016, Blast_Score=242, Evalue=8e-64,
Organism=Caenorhabditis elegans, GI71997168, Length=454, Percent_Identity=32.8193832599119, Blast_Score=227, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71997163, Length=454, Percent_Identity=32.8193832599119, Blast_Score=227, Evalue=3e-59,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1159, Percent_Identity=47.886108714409, Blast_Score=1087, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1161, Percent_Identity=48.062015503876, Blast_Score=1070, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=462, Percent_Identity=38.7445887445887, Blast_Score=318, Evalue=3e-87,
Organism=Saccharomyces cerevisiae, GI6323863, Length=438, Percent_Identity=34.0182648401827, Blast_Score=239, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6324343, Length=514, Percent_Identity=31.3229571984436, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24652212, Length=1152, Percent_Identity=49.21875, Blast_Score=1125, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1152, Percent_Identity=49.21875, Blast_Score=1125, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1152, Percent_Identity=49.21875, Blast_Score=1125, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1152, Percent_Identity=49.21875, Blast_Score=1125, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1152, Percent_Identity=49.21875, Blast_Score=1125, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1166, Percent_Identity=48.6277873070326, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1166, Percent_Identity=48.6277873070326, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1166, Percent_Identity=48.6277873070326, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1166, Percent_Identity=48.6277873070326, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1166, Percent_Identity=48.6277873070326, Blast_Score=1120, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=456, Percent_Identity=40.1315789473684, Blast_Score=355, Evalue=1e-97,
Organism=Drosophila melanogaster, GI24651759, Length=415, Percent_Identity=39.7590361445783, Blast_Score=315, Evalue=1e-85,
Organism=Drosophila melanogaster, GI161076409, Length=505, Percent_Identity=31.4851485148515, Blast_Score=248, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586458, Length=505, Percent_Identity=31.4851485148515, Blast_Score=248, Evalue=2e-65,
Organism=Drosophila melanogaster, GI161076407, Length=505, Percent_Identity=31.4851485148515, Blast_Score=248, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586460, Length=505, Percent_Identity=31.4851485148515, Blast_Score=248, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 127826; Mature: 127826

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFKRVLVANRGEIAIRVFRACHELGIRTVAIYSEEDKFSLFRTKADEAYLIGKNKGPI
CCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHEEECCCCEEEEECCCCCC
DAYLNIEEIIQLALKKGVDAIHPGYGFLAENSEFARKCREAGIEFIGPTAEMMEKLGDKI
CEEECHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHCCCEEECCHHHHHHHHHHHH
KSKIVAEKAGVPTIPGVQKPIKSEKEALEFARYCGYPIMLKAAAGGGGRGMRIVRTEEEL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECHHHH
ISSFKSAKNEAKKAFGIDDIFIEKYLENPKHIEVQILGDKHGDIVHLYERDCSIQRRHQK
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHH
VIEFTPAFALPKKKREEICNDALKIAKTVGYRSAGTLEFLVDTTGNHYFIEMNPRIQVEH
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCEEEHH
TVTEMITGIDIVQSQILIAEGYKLDSEEVGIKSQESIQTRGYAIQCRVTTEDPSNNFAPD
HHHHHHHHHHHHHHHEEEECCCCCCHHHCCCCCHHHHHHCCEEEEEEEECCCCCCCCCCC
TGKIEDYRTGSGFGIRLDGGNGFTGSVISPYYDSLLVKTTSWSRTFNDAIRKSIRAIKEF
CCCCCCEECCCCEEEEEECCCCCCCCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHHHH
KIDGVKTNIGFLINVLNHEQFRKGQCDTNFIEKNPELFDITSKTDDEVRILKFIGEKVVN
CCCCEEECHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEECCCCCCHHHHHHHHHHHHHH
ETHGIKKDFDVPTIPIVDEGLSLKGTKQILDEKGPEGLVSWIKTQNKLLLTDTTMRDAHQ
HHCCCCCCCCCCCCCEECCCCCCCCHHHHHHCCCHHHHHHHHHCCCCEEEEECHHHHHHH
SLMATRMRSVDMFKIAKAQSVLGKDLFSMEMWGGATFDVAYRFLKESPWTRLEELRKSIP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
NVLFQMLIRGANAVGYKNYPDNVIRKFIKQSADSGIDVFRIFDSLNWLKGMEVATDEVLK
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
QNKVAETCMCYTGDILEGYRDKYSLQYYVDLAKDIEKTGAHILGIKDMSALLKPYAAVKL
HHHHHHHHHHHCCHHHHHHHHCCEEHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHH
IKALKNEISIPIHLHTHDTTGNGVATVLMAAHAGVDIVDTAFNSMSGLTSQPALNSIVAA
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHH
LENTDRETGLDLTDMQKLSDYWSAVRPVYSQLESGLKSGSAEIYKYEIPGGQYSNLKPQV
HHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCH
ESFGLGHKFEEVKEMYKKVNEMLGDIIKVTPSSKVVGDLAIFMVKNDLTPENIYEKAEKM
HHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHEEEEEEECCCCHHHHHHHHHHH
AFPDSAVSYFKGMMGQPMGGFPEKLQKLVLKGEDPITCRPGEMLPPEDFEKIREHLKEKH
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHC
DLDATENDIISYALYPEVFDKYLDFLKEYGDLSHMGSDVFFHGLYEGETAEIELQEGKTF
CCCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCEEEEEEECCCEE
IVQLSEIGKVDSEGNRAVVFEINGNRREIRIKDKSSLMAQNITSNSTKMADPANKKHIGS
EEEEHHHCCCCCCCCEEEEEEECCCEEEEEEECHHHHHHHHCCCCCCCCCCCCCHHHCCC
SIPGTVIKVLVNKGDEIKEGDSLIVIEAMKMETNIVASLSGVVGSLLVKEGDQVKSGQLL
CCCHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LELE
EEEC
>Mature Secondary Structure
MNKFKRVLVANRGEIAIRVFRACHELGIRTVAIYSEEDKFSLFRTKADEAYLIGKNKGPI
CCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHEEECCCCEEEEECCCCCC
DAYLNIEEIIQLALKKGVDAIHPGYGFLAENSEFARKCREAGIEFIGPTAEMMEKLGDKI
CEEECHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHCCCEEECCHHHHHHHHHHHH
KSKIVAEKAGVPTIPGVQKPIKSEKEALEFARYCGYPIMLKAAAGGGGRGMRIVRTEEEL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECHHHH
ISSFKSAKNEAKKAFGIDDIFIEKYLENPKHIEVQILGDKHGDIVHLYERDCSIQRRHQK
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCHHHHHHHH
VIEFTPAFALPKKKREEICNDALKIAKTVGYRSAGTLEFLVDTTGNHYFIEMNPRIQVEH
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCEEEHH
TVTEMITGIDIVQSQILIAEGYKLDSEEVGIKSQESIQTRGYAIQCRVTTEDPSNNFAPD
HHHHHHHHHHHHHHHEEEECCCCCCHHHCCCCCHHHHHHCCEEEEEEEECCCCCCCCCCC
TGKIEDYRTGSGFGIRLDGGNGFTGSVISPYYDSLLVKTTSWSRTFNDAIRKSIRAIKEF
CCCCCCEECCCCEEEEEECCCCCCCCCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHHHH
KIDGVKTNIGFLINVLNHEQFRKGQCDTNFIEKNPELFDITSKTDDEVRILKFIGEKVVN
CCCCEEECHHHHHHHHHHHHHHCCCCCCCHHHCCCCEEEECCCCCCHHHHHHHHHHHHHH
ETHGIKKDFDVPTIPIVDEGLSLKGTKQILDEKGPEGLVSWIKTQNKLLLTDTTMRDAHQ
HHCCCCCCCCCCCCCEECCCCCCCCHHHHHHCCCHHHHHHHHHCCCCEEEEECHHHHHHH
SLMATRMRSVDMFKIAKAQSVLGKDLFSMEMWGGATFDVAYRFLKESPWTRLEELRKSIP
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
NVLFQMLIRGANAVGYKNYPDNVIRKFIKQSADSGIDVFRIFDSLNWLKGMEVATDEVLK
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
QNKVAETCMCYTGDILEGYRDKYSLQYYVDLAKDIEKTGAHILGIKDMSALLKPYAAVKL
HHHHHHHHHHHCCHHHHHHHHCCEEHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHH
IKALKNEISIPIHLHTHDTTGNGVATVLMAAHAGVDIVDTAFNSMSGLTSQPALNSIVAA
HHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHH
LENTDRETGLDLTDMQKLSDYWSAVRPVYSQLESGLKSGSAEIYKYEIPGGQYSNLKPQV
HHCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCH
ESFGLGHKFEEVKEMYKKVNEMLGDIIKVTPSSKVVGDLAIFMVKNDLTPENIYEKAEKM
HHCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHEEEEEEECCCCHHHHHHHHHHH
AFPDSAVSYFKGMMGQPMGGFPEKLQKLVLKGEDPITCRPGEMLPPEDFEKIREHLKEKH
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCCHHHHHHHHHHHHHC
DLDATENDIISYALYPEVFDKYLDFLKEYGDLSHMGSDVFFHGLYEGETAEIELQEGKTF
CCCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHCCCCCEEEEEECCCEEEEEEECCCEE
IVQLSEIGKVDSEGNRAVVFEINGNRREIRIKDKSSLMAQNITSNSTKMADPANKKHIGS
EEEEHHHCCCCCCCCEEEEEEECCCEEEEEEECHHHHHHHHCCCCCCCCCCCCCHHHCCC
SIPGTVIKVLVNKGDEIKEGDSLIVIEAMKMETNIVASLSGVVGSLLVKEGDQVKSGQLL
CCCHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
LELE
EEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]