| Definition | Clostridium botulinum A2 str. Kyoto chromosome, complete genome. |
|---|---|
| Accession | NC_012563 |
| Length | 4,155,278 |
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The map label for this gene is flhA [H]
Identifier: 226950058
GI number: 226950058
Start: 3011574
End: 3013640
Strand: Reverse
Name: flhA [H]
Synonym: CLM_3011
Alternate gene names: 226950058
Gene position: 3013640-3011574 (Counterclockwise)
Preceding gene: 226950059
Following gene: 226950057
Centisome position: 72.53
GC content: 32.37
Gene sequence:
>2067_bases GTGGAAGGTACTAATAATAGATTTAAAATAAAAAACAGTATAGATGTTATTGCGGCTTTTGGAGTTGTAGGGATTGTATT AATGATAATAATACCTCTTCCTTCTGCAATTTTAGATGTACTTTTAGCTTTTAATATAACTCTTTCTGTGGTTATAATTT TAATTACTATGTTTACCACAGAAGTTCTTCAGTTTTCATCTTTTCCTACATTACTATTAATAACTACTCTTTTTAGATTA GGGCTGAATATTTCTTCTACTAGACTTATACTAAGGGATGCCTATGCCGGAAAAATAATAGAAACCTTTGGAAGTCTTGT TACAGGAGGAAATTATGTTATAGGTATAATAATATTTCTTATTATAGTTATAATACAATTTGTAGTTATAACTAGTGGTG CGTCAAGGGTATCAGAGGTTTCTGCTAGATTTACTTTAGATGCTATGCCAGGAAAGCAAATGAGTATAGATGCAGATTTG AATGCAGGACTTATAGATGAACAAGGAGCAAAAGAAAAAAGACAAAATCTTCAAAAAGAAGCGGATTTTTATGGATCCAT GGATGGTGCTTCTAAATTTGTAAAGGGAGATGCAGTAGCAGGACTTATAATAACTTTTATAAATATAATTGCAGGTATAA TAATAGGAGTTGTTATGTTGAAAATGGATATAGCTACGGCAGCTCAAACTTACATAAGACTTACTATAGGGGATGGATTG GTAGGACAAATACCTGCCCTTTTAATATCTACAGCCTCTGGTATATTAGTTACTAGATCTGGAAGCGATGAGAATTTGGG AACAGTTCTTAGTAAACAATTAACAGGATTTCCAAAGGTTTTAGCCATAGCATCTGTAGTACTTTTATTTTTAGCTATGA TTCCAGGGCTTCCTCATTTAGCGTTTTTAATATTGTCTATAGCTAATGCAGTAGCTGCTTATCTTTTATTTAAAGAAGAA AAAGAACAGGTTATTATGCAAGAAGAAGCTCAGCAAATGGAAATTACAGAAATAGAAAGTAAAGAACCAGAAAATGTTAT GAATTTAGTATCTGTAGAACCTATGGAAGTAGAAATAGGATATGGGCTTATACCTTTGGCAGATGAATCCGCAGGAGGGG ATCTTCTTCAAAGAATAACTTCTGTAAGAAGACAATGTGCTATTGAGATGGGAGTAGTAGTTCAACCTATAAGGATAAGA GATAATCTACAGCTTAAAACTAATGAATATATAATAAAAATTAGAGGAACCACTATAACAAAAGGAGAGCTTATGCCTAA TATGCTTCTTTGTATGGATCCTACAGGAGAAGTAGAAATACCAGGGATAAAGGGGATAGAACCAGCCTTTGGACTTCCAG CTGTATGGGTTAATAAAGACCAAAGAGAAGAGGCAGAACTTAAAGGTTTAACAGTGGTAGATCCTACTACAGTTATGGTT ACTCATTTAACTGAAATAATAAAGAATCATTCCTATGAACTTTTAGGAAGACAGGAAGTAAAATTAATATTAGATTCTAT GAAGGAAAAATATAGTGCTGTTACAGAGGAACTTATACCAGATCTTATGACTATAGGAGAAATTCAAAAGGTTCTTCAAA ATCTATTAAAAGAAAGAGTATCCATAAAGGATATGGTTACTATATTAGAATCTTTAGCGGATAATTCTAGAAATACAAAA GACATAGAAGTTTTAACAGAGTATGTGAGATTTTCTTTGGCTAGAAGTATATGCAATCCATTAATAGATGAAAATGGAGC GTTAACCGTAATAACTTTAGATCCAAGTATTGAGCAAACTATAAACAATAATATACAAAAATCTATGCAGGGTTCTTTTC CTGCTTTAGATCCAGATACTACTAGTAGTATACTAAATGGATTAAAGCAAAAATTAGATGAAGTATATTTTTATAATAAT CAAGCAGTAGTTTTGGTTTCACCAAATATAAGGCCAGCTTTTAGAAGGCTTATAGAGATGGTATTTCCAGCGGTGAACGT ACTTTCTTTAAATGAAGTACCTAACGATGTGGAAATGAGAACTGAAGGAGTGGTTACGCTACAATGA
Upstream 100 bases:
>100_bases AGTACCACAGGATATGTATGAAGCAGTAGCGGAAATATTAGCTATAGTTTATACTTTAAAAAAGAAAAAATAAACTAGGT ATACAAAATGAGGTGATTTA
Downstream 100 bases:
>100_bases AAATAAAAAAATATGTAGTCAATGATATGAATGAAGCAATGACTAGAATTCGTTATGAACTCGGAGCAGATGCTATAATA ATAAGTCAAAGAAAAGTAAG
Product: flagellar biosynthesis protein FlhA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 688; Mature: 688
Protein sequence:
>688_residues MEGTNNRFKIKNSIDVIAAFGVVGIVLMIIIPLPSAILDVLLAFNITLSVVIILITMFTTEVLQFSSFPTLLLITTLFRL GLNISSTRLILRDAYAGKIIETFGSLVTGGNYVIGIIIFLIIVIIQFVVITSGASRVSEVSARFTLDAMPGKQMSIDADL NAGLIDEQGAKEKRQNLQKEADFYGSMDGASKFVKGDAVAGLIITFINIIAGIIIGVVMLKMDIATAAQTYIRLTIGDGL VGQIPALLISTASGILVTRSGSDENLGTVLSKQLTGFPKVLAIASVVLLFLAMIPGLPHLAFLILSIANAVAAYLLFKEE KEQVIMQEEAQQMEITEIESKEPENVMNLVSVEPMEVEIGYGLIPLADESAGGDLLQRITSVRRQCAIEMGVVVQPIRIR DNLQLKTNEYIIKIRGTTITKGELMPNMLLCMDPTGEVEIPGIKGIEPAFGLPAVWVNKDQREEAELKGLTVVDPTTVMV THLTEIIKNHSYELLGRQEVKLILDSMKEKYSAVTEELIPDLMTIGEIQKVLQNLLKERVSIKDMVTILESLADNSRNTK DIEVLTEYVRFSLARSICNPLIDENGALTVITLDPSIEQTINNNIQKSMQGSFPALDPDTTSSILNGLKQKLDEVYFYNN QAVVLVSPNIRPAFRRLIEMVFPAVNVLSLNEVPNDVEMRTEGVVTLQ
Sequences:
>Translated_688_residues MEGTNNRFKIKNSIDVIAAFGVVGIVLMIIIPLPSAILDVLLAFNITLSVVIILITMFTTEVLQFSSFPTLLLITTLFRL GLNISSTRLILRDAYAGKIIETFGSLVTGGNYVIGIIIFLIIVIIQFVVITSGASRVSEVSARFTLDAMPGKQMSIDADL NAGLIDEQGAKEKRQNLQKEADFYGSMDGASKFVKGDAVAGLIITFINIIAGIIIGVVMLKMDIATAAQTYIRLTIGDGL VGQIPALLISTASGILVTRSGSDENLGTVLSKQLTGFPKVLAIASVVLLFLAMIPGLPHLAFLILSIANAVAAYLLFKEE KEQVIMQEEAQQMEITEIESKEPENVMNLVSVEPMEVEIGYGLIPLADESAGGDLLQRITSVRRQCAIEMGVVVQPIRIR DNLQLKTNEYIIKIRGTTITKGELMPNMLLCMDPTGEVEIPGIKGIEPAFGLPAVWVNKDQREEAELKGLTVVDPTTVMV THLTEIIKNHSYELLGRQEVKLILDSMKEKYSAVTEELIPDLMTIGEIQKVLQNLLKERVSIKDMVTILESLADNSRNTK DIEVLTEYVRFSLARSICNPLIDENGALTVITLDPSIEQTINNNIQKSMQGSFPALDPDTTSSILNGLKQKLDEVYFYNN QAVVLVSPNIRPAFRRLIEMVFPAVNVLSLNEVPNDVEMRTEGVVTLQ >Mature_688_residues MEGTNNRFKIKNSIDVIAAFGVVGIVLMIIIPLPSAILDVLLAFNITLSVVIILITMFTTEVLQFSSFPTLLLITTLFRL GLNISSTRLILRDAYAGKIIETFGSLVTGGNYVIGIIIFLIIVIIQFVVITSGASRVSEVSARFTLDAMPGKQMSIDADL NAGLIDEQGAKEKRQNLQKEADFYGSMDGASKFVKGDAVAGLIITFINIIAGIIIGVVMLKMDIATAAQTYIRLTIGDGL VGQIPALLISTASGILVTRSGSDENLGTVLSKQLTGFPKVLAIASVVLLFLAMIPGLPHLAFLILSIANAVAAYLLFKEE KEQVIMQEEAQQMEITEIESKEPENVMNLVSVEPMEVEIGYGLIPLADESAGGDLLQRITSVRRQCAIEMGVVVQPIRIR DNLQLKTNEYIIKIRGTTITKGELMPNMLLCMDPTGEVEIPGIKGIEPAFGLPAVWVNKDQREEAELKGLTVVDPTTVMV THLTEIIKNHSYELLGRQEVKLILDSMKEKYSAVTEELIPDLMTIGEIQKVLQNLLKERVSIKDMVTILESLADNSRNTK DIEVLTEYVRFSLARSICNPLIDENGALTVITLDPSIEQTINNNIQKSMQGSFPALDPDTTSSILNGLKQKLDEVYFYNN QAVVLVSPNIRPAFRRLIEMVFPAVNVLSLNEVPNDVEMRTEGVVTLQ
Specific function: Involved in the export of flagellum proteins [H]
COG id: COG1298
COG function: function code NU; Flagellar biosynthesis pathway, component FlhA
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]
Homologues:
Organism=Escherichia coli, GI1788187, Length=664, Percent_Identity=42.1686746987952, Blast_Score=510, Evalue=1e-145,
Paralogues:
None
Copy number: 10-20 (rich media) [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006301 - InterPro: IPR001712 [H]
Pfam domain/function: PF00771 FHIPEP [H]
EC number: NA
Molecular weight: Translated: 75350; Mature: 75350
Theoretical pI: Translated: 4.53; Mature: 4.53
Prosite motif: PS00994 FHIPEP
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 3.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 3.5 %Met (Mature Protein) 3.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEGTNNRFKIKNSIDVIAAFGVVGIVLMIIIPLPSAILDVLLAFNITLSVVIILITMFTT CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH EVLQFSSFPTLLLITTLFRLGLNISSTRLILRDAYAGKIIETFGSLVTGGNYVIGIIIFL HHHHHCCCCHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHH IIVIIQFVVITSGASRVSEVSARFTLDAMPGKQMSIDADLNAGLIDEQGAKEKRQNLQKE HHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHH ADFYGSMDGASKFVKGDAVAGLIITFINIIAGIIIGVVMLKMDIATAAQTYIRLTIGDGL HHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC VGQIPALLISTASGILVTRSGSDENLGTVLSKQLTGFPKVLAIASVVLLFLAMIPGLPHL HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHH AFLILSIANAVAAYLLFKEEKEQVIMQEEAQQMEITEIESKEPENVMNLVSVEPMEVEIG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEC YGLIPLADESAGGDLLQRITSVRRQCAIEMGVVVQPIRIRDNLQLKTNEYIIKIRGTTIT CCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEECEEECCCCEEECCCEEEEEECCEEE KGELMPNMLLCMDPTGEVEIPGIKGIEPAFGLPAVWVNKDQREEAELKGLTVVDPTTVMV CCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCEEEECCCCHHHHHHCCCEEECCHHHHH THLTEIIKNHSYELLGRQEVKLILDSMKEKYSAVTEELIPDLMTIGEIQKVLQNLLKERV HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SIKDMVTILESLADNSRNTKDIEVLTEYVRFSLARSICNPLIDENGALTVITLDPSIEQT HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHH INNNIQKSMQGSFPALDPDTTSSILNGLKQKLDEVYFYNNQAVVLVSPNIRPAFRRLIEM HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCHHHHHHHHH VFPAVNVLSLNEVPNDVEMRTEGVVTLQ HHHHHCEEECCCCCCCHHCCCCCCEEEC >Mature Secondary Structure MEGTNNRFKIKNSIDVIAAFGVVGIVLMIIIPLPSAILDVLLAFNITLSVVIILITMFTT CCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH EVLQFSSFPTLLLITTLFRLGLNISSTRLILRDAYAGKIIETFGSLVTGGNYVIGIIIFL HHHHHCCCCHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHH IIVIIQFVVITSGASRVSEVSARFTLDAMPGKQMSIDADLNAGLIDEQGAKEKRQNLQKE HHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHH ADFYGSMDGASKFVKGDAVAGLIITFINIIAGIIIGVVMLKMDIATAAQTYIRLTIGDGL HHHCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC VGQIPALLISTASGILVTRSGSDENLGTVLSKQLTGFPKVLAIASVVLLFLAMIPGLPHL HHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHH AFLILSIANAVAAYLLFKEEKEQVIMQEEAQQMEITEIESKEPENVMNLVSVEPMEVEIG HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEC YGLIPLADESAGGDLLQRITSVRRQCAIEMGVVVQPIRIRDNLQLKTNEYIIKIRGTTIT CCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCEEECEEECCCCEEECCCEEEEEECCEEE KGELMPNMLLCMDPTGEVEIPGIKGIEPAFGLPAVWVNKDQREEAELKGLTVVDPTTVMV CCCCCCCEEEEECCCCCEECCCCCCCCCCCCCCEEEECCCCHHHHHHCCCEEECCHHHHH THLTEIIKNHSYELLGRQEVKLILDSMKEKYSAVTEELIPDLMTIGEIQKVLQNLLKERV HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SIKDMVTILESLADNSRNTKDIEVLTEYVRFSLARSICNPLIDENGALTVITLDPSIEQT HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHH INNNIQKSMQGSFPALDPDTTSSILNGLKQKLDEVYFYNNQAVVLVSPNIRPAFRRLIEM HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCEEEEEECCCCCHHHHHHHHH VFPAVNVLSLNEVPNDVEMRTEGVVTLQ HHHHHCEEECCCCCCCHHCCCCCCEEEC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 8097015; 9384377 [H]