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The map label for this gene is flhF [H]

Identifier: 226950057

GI number: 226950057

Start: 3010351

End: 3011577

Strand: Reverse

Name: flhF [H]

Synonym: CLM_3010

Alternate gene names: 226950057

Gene position: 3011577-3010351 (Counterclockwise)

Preceding gene: 226950058

Following gene: 226950056

Centisome position: 72.48

GC content: 26.98

Gene sequence:

>1227_bases
ATGAAAATAAAAAAATATGTAGTCAATGATATGAATGAAGCAATGACTAGAATTCGTTATGAACTCGGAGCAGATGCTAT
AATAATAAGTCAAAGAAAAGTAAGAAAGGGAGGCTTTTTAGGCCTCTTTTCTAAAAAATCCTTAGAAGTTACCGCAGCTA
TAGATAACCATTCAACAGAAAAAAAATATAACTATAATACTGTAAATAAAATCAATAAAGGAAATAATATAGAAGTTATT
AAAAGGATGATAGAAGAAAGAAATAATAATGTTAAATATGATAACAACATAAATCATGATACTAATGTATTAGATAGTTA
TAAGGAAATTTTAGAATCTAAAAGTGAAAGCTTTCAAAATAAGAGTTTTAAAGGGAAAGAGTTTTCAGAAACAAAAGATT
TAATGAACGAAATAAAGGATTTAAAGAAAATAGTTAAGGATATAGGAAAAAGTGAAAAATCTTATGCAGATGAAAACTCC
TCATTAGTAAATTTTTTTAAGGATTTGGATTTAGAAGAAGAATTTATTGAAAAAATAATAAAAAAAGTAGGTGATTTAGA
GGATAATTTAGAAGAAAGAGAGAAAATAAAAAGAGTAATAGAAGATACTATAGATGTTAGAGTAAATTCTGTAGGTAAGG
TTACTGTCTTGGTAGGGCCAACTGGTGTAGGTAAAACTACAACAATTGCAAAGTTAGCAGGTAAACTTTCTTTAATAGAC
AAAAAGAAAGTAGGGCTCATAACTATAGATACCTATAGAATAGGTGCGGTAGAACAACTAAAAACTTACGCTGATATTAT
GAATATTCCATTTAAGGTAGTATTTTCCATGAAGGATATGGAAAAAGCTATTATAGATTTAGACTATTGTGATGTTATAT
TAGTAGATACTACAGGGAGAAGTAGTAAAAATATGATGCAGATATCAGAGTTAAGGGCTTTTATAGAGAAAATAAAAGAA
AAATCAGTGCATTTAGTAATAAGTGCTTCTACTAAAAATAAGGATGTAGAAACTATAATAAAAGGGTATTCTATTTTAGA
ATATGAAAATATAATAATAACAAAGCTAGATGAAACTAGTATCTATGGTTCAATTTTAACTGTATTAGATAAAGGTAAAA
AACCTATTAGTTTTATAACCACAGGTCAAGATGTACCAGATGATATAAAGGAAGGAAACAAAGAGGAAATAGCAAAGATT
GTATTAGGAGAGAATAAATTATGCTAG

Upstream 100 bases:

>100_bases
GAAGGCTTATAGAGATGGTATTTCCAGCGGTGAACGTACTTTCTTTAAATGAAGTACCTAACGATGTGGAAATGAGAACT
GAAGGAGTGGTTACGCTACA

Downstream 100 bases:

>100_bases
ACCAGGCAGAAAAACTTAGACAATTAGTAAATAATAAGGCTGGAAGTGTAAATTCCCCTAAAATAATTACAGTAACATCT
GGTAAAGGAGGAGTGGGAAA

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKVRKGGFLGLFSKKSLEVTAAIDNHSTEKKYNYNTVNKINKGNNIEVI
KRMIEERNNNVKYDNNINHDTNVLDSYKEILESKSESFQNKSFKGKEFSETKDLMNEIKDLKKIVKDIGKSEKSYADENS
SLVNFFKDLDLEEEFIEKIIKKVGDLEDNLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSMKDMEKAIIDLDYCDVILVDTTGRSSKNMMQISELRAFIEKIKE
KSVHLVISASTKNKDVETIIKGYSILEYENIIITKLDETSIYGSILTVLDKGKKPISFITTGQDVPDDIKEGNKEEIAKI
VLGENKLC

Sequences:

>Translated_408_residues
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKVRKGGFLGLFSKKSLEVTAAIDNHSTEKKYNYNTVNKINKGNNIEVI
KRMIEERNNNVKYDNNINHDTNVLDSYKEILESKSESFQNKSFKGKEFSETKDLMNEIKDLKKIVKDIGKSEKSYADENS
SLVNFFKDLDLEEEFIEKIIKKVGDLEDNLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSMKDMEKAIIDLDYCDVILVDTTGRSSKNMMQISELRAFIEKIKE
KSVHLVISASTKNKDVETIIKGYSILEYENIIITKLDETSIYGSILTVLDKGKKPISFITTGQDVPDDIKEGNKEEIAKI
VLGENKLC
>Mature_408_residues
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKVRKGGFLGLFSKKSLEVTAAIDNHSTEKKYNYNTVNKINKGNNIEVI
KRMIEERNNNVKYDNNINHDTNVLDSYKEILESKSESFQNKSFKGKEFSETKDLMNEIKDLKKIVKDIGKSEKSYADENS
SLVNFFKDLDLEEEFIEKIIKKVGDLEDNLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSMKDMEKAIIDLDYCDVILVDTTGRSSKNMMQISELRAFIEKIKE
KSVHLVISASTKNKDVETIIKGYSILEYENIIITKLDETSIYGSILTVLDKGKKPISFITTGQDVPDDIKEGNKEEIAKI
VLGENKLC

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=203, Percent_Identity=30.0492610837438, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=30.0492610837438, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789874, Length=199, Percent_Identity=33.1658291457286, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788963, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17539958, Length=183, Percent_Identity=31.6939890710383, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325345, Length=197, Percent_Identity=31.4720812182741, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17647949, Length=183, Percent_Identity=30.6010928961749, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 46284; Mature: 46284

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKVRKGGFLGLFSKKSLEVTAAIDNHSTE
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCEEEEECCCCEEEEEEECCCCCC
KKYNYNTVNKINKGNNIEVIKRMIEERNNNVKYDNNINHDTNVLDSYKEILESKSESFQN
CCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
KSFKGKEFSETKDLMNEIKDLKKIVKDIGKSEKSYADENSSLVNFFKDLDLEEEFIEKII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHH
KKVGDLEDNLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
HHHCCHHCCHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHEEC
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSMKDMEKAIIDLDYCDVILVDTTGR
CCCCCEEEEECEECCHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHCCCCCCEEEEECCCC
SSKNMMQISELRAFIEKIKEKSVHLVISASTKNKDVETIIKGYSILEYENIIITKLDETS
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCEEEECCEEEEECCCHH
IYGSILTVLDKGKKPISFITTGQDVPDDIKEGNKEEIAKIVLGENKLC
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKIKKYVVNDMNEAMTRIRYELGADAIIISQRKVRKGGFLGLFSKKSLEVTAAIDNHSTE
CCCHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHCCCCEEEEECCCCEEEEEEECCCCCC
KKYNYNTVNKINKGNNIEVIKRMIEERNNNVKYDNNINHDTNVLDSYKEILESKSESFQN
CCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
KSFKGKEFSETKDLMNEIKDLKKIVKDIGKSEKSYADENSSLVNFFKDLDLEEEFIEKII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHCCCCHHHHHHHH
KKVGDLEDNLEEREKIKRVIEDTIDVRVNSVGKVTVLVGPTGVGKTTTIAKLAGKLSLID
HHHCCHHCCHHHHHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHEEC
KKKVGLITIDTYRIGAVEQLKTYADIMNIPFKVVFSMKDMEKAIIDLDYCDVILVDTTGR
CCCCCEEEEECEECCHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHCCCCCCEEEEECCCC
SSKNMMQISELRAFIEKIKEKSVHLVISASTKNKDVETIIKGYSILEYENIIITKLDETS
CCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCEEEECCEEEEECCCHH
IYGSILTVLDKGKKPISFITTGQDVPDDIKEGNKEEIAKIVLGENKLC
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168127; 9403685 [H]