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The map label for this gene is ntpI [H]

Identifier: 226950041

GI number: 226950041

Start: 2992960

End: 2994921

Strand: Reverse

Name: ntpI [H]

Synonym: CLM_2994

Alternate gene names: 226950041

Gene position: 2994921-2992960 (Counterclockwise)

Preceding gene: 226950042

Following gene: 226950040

Centisome position: 72.08

GC content: 30.07

Gene sequence:

>1962_bases
ATGGGAATAGCTAAGATGAAAAAATTTACTTTATTAGCCCTTGAATCACATAAGGAATCTCTTTTTGAAGCTATGCAAAA
GTTTCAAGAAGTACAGTTTGTTAACCTACAAGAAGAAAAGTCAGAAAAGTTAGAGTTTATGCAAAATGACTCTCAGTCAG
AGCTGGTATCAGACTTGGAAGGTAAACAAGCTAAACTTAAATTTTGTTTAGATATTTTAGAAAGATATGTACAAAAAGAA
AAGGGACTCAAGGCTCTTATGAAGGGTAAAAAATTCATGGATTATAATGAGCTTAAAAATTTAGGCGAGAACATAGAGTG
GATGAGTATTTATAATACTTTAAGAGAAAAGGATACAAAACTTAGTGCCTTAAAAAATGAAATATCTAAACCAAAAGGTG
AAATAAAAGCATTGGAGCCTTGGATTAATTTTGATGAAAAAATTAGTAAGGCTAAGTTTAATACTAGTACTTCTTATTTA
GGGGTATTACCTTTAAATTACAAAGATGAGTTTAGAGAGACTTTTGACTCAGAGATACCTGTTTCTTATGTAGAAACTAT
AGGGGAAAATAAAGATGGAGTTTATTTGTTTGTAGTATTTCATAATGATTACTTTAAAGAAGCTTCGGAAGTATTAAAAA
GGTATGGCTTTAGTAAAATAGCTTTTAACTATGATGATTCTCCTAAAGAGACTATAAAAGCTTTAGAAGAAGAAATAAAG
TCTATTAAAAAAGAAGAAATAAAAACTATAGAAGGAATAAAAGTATTTACTAATAAATTAGAAGATCTTCAAATAGCTTA
TGAGTATATTAGTTTACAGGTTGACAGAGAAAAAGCATCTATGAATATCTTAAAAACAGATAGAATAGTGGCTATTGAGG
GTTGGGTACCAAAGGATTCTATGGAAGAATTAGAAGGCTTAATAAGACAATCCGAAGGTGAATTATATTATATAGAATTC
AATGACCCTTTAGATGAAGAAGAAGAAAAGGTTCCAATAATGTTAAAGAACAATAAGATAGTTGAGCCTTTTGAATCTAT
TACAGCTATGTATAGCCTTCCGAAGTATAAGGAAATAGATCCTACGCCAGCTTTAGTACCTTTTTATTTAATATTCTTTG
GAATGATGTTATCGGATGCAGGTTATGGTTTAATTATGCTTATATGTACTTTACTAGCTCTTAAAACTATACCAATGGAA
AAAGCAACTAAACAAATGATTAAGTTATTATATTACTTAAGTTATCCAACCATAGTTTGGGGCGCGCTTTATGGCAGTTA
TTTTGGAGGTATTATAAACATACCGGCCATATGGGTAAAACCAGAAGATAGTGTATCATCAATTTTAATTATATCCATAG
TTTTTGGTATAATTCACCTATACACAGGACTTGGTGTAAAAGCTTATATGTTAATTAGAAACAAAAGATATAAAGATGCA
TTTTACGATGTAGGTTTATGGTATATAACTTTAACTACAGCTATAATTATAGTAGCTGCAAATTTCGGAAATATAACTGC
ATTAAATCCATACATAAACCCTTGTAAATATATAATGTATGCAGGTATGGTAGGTTTAGTTTTAACTCAAGGTAGAGAAA
ACAAAACAATAGGAGCAAAACTTGGTGCAGGTTTATATGGATTATATGGTATTACAAGTTATGTAGGAGATATAGTTTCT
TATTCAAGGCTTATGGCTTTGGGGCTTGCTACAGGATTTATAGGTGGAGCTTTTAACTTAATGATAAGCCTTTTAGGTAA
TGGAGTTAAAGCTTGGGTATTTGGAACATTAATATTTGTTGTAGGTCACGTGTTTAATTTGCTTATAAATGCATTAGGTG
CTTATGTTCACACTTGTAGATTACAGTATGTTGAATATTTCGGCAAGTTTTATGAAGGGGGAGGAAAACCATTTACTCCT
TTCAAACCAAATAATAAATACATTAACATAATAAAAGATTAG

Upstream 100 bases:

>100_bases
CTAAAAGAGGGGGAAAAATCCTTAGAAAGTATAAAAAATATTTCTAAGGATAAATTTGAAAAGGCTACAAATATAGTGAT
TGAGAGGATAGTGAAAGTTA

Downstream 100 bases:

>100_bases
GAGGAGTCTATTATGGAAAATATAACATTAATGAATTTTTTAACACAAAACGGGGGAGCAATATTTGCTGCTATAGGGGT
AGCATTAGCGGCTATAATGC

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: Na(+)-translocating ATPase subunit I; V-type sodium pump subunit I [H]

Number of amino acids: Translated: 653; Mature: 652

Protein sequence:

>653_residues
MGIAKMKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLEGKQAKLKFCLDILERYVQKE
KGLKALMKGKKFMDYNELKNLGENIEWMSIYNTLREKDTKLSALKNEISKPKGEIKALEPWINFDEKISKAKFNTSTSYL
GVLPLNYKDEFRETFDSEIPVSYVETIGENKDGVYLFVVFHNDYFKEASEVLKRYGFSKIAFNYDDSPKETIKALEEEIK
SIKKEEIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAIEGWVPKDSMEELEGLIRQSEGELYYIEF
NDPLDEEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEIDPTPALVPFYLIFFGMMLSDAGYGLIMLICTLLALKTIPME
KATKQMIKLLYYLSYPTIVWGALYGSYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDA
FYDVGLWYITLTTAIIIVAANFGNITALNPYINPCKYIMYAGMVGLVLTQGRENKTIGAKLGAGLYGLYGITSYVGDIVS
YSRLMALGLATGFIGGAFNLMISLLGNGVKAWVFGTLIFVVGHVFNLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTP
FKPNNKYINIIKD

Sequences:

>Translated_653_residues
MGIAKMKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLEGKQAKLKFCLDILERYVQKE
KGLKALMKGKKFMDYNELKNLGENIEWMSIYNTLREKDTKLSALKNEISKPKGEIKALEPWINFDEKISKAKFNTSTSYL
GVLPLNYKDEFRETFDSEIPVSYVETIGENKDGVYLFVVFHNDYFKEASEVLKRYGFSKIAFNYDDSPKETIKALEEEIK
SIKKEEIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAIEGWVPKDSMEELEGLIRQSEGELYYIEF
NDPLDEEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEIDPTPALVPFYLIFFGMMLSDAGYGLIMLICTLLALKTIPME
KATKQMIKLLYYLSYPTIVWGALYGSYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDA
FYDVGLWYITLTTAIIIVAANFGNITALNPYINPCKYIMYAGMVGLVLTQGRENKTIGAKLGAGLYGLYGITSYVGDIVS
YSRLMALGLATGFIGGAFNLMISLLGNGVKAWVFGTLIFVVGHVFNLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTP
FKPNNKYINIIKD
>Mature_652_residues
GIAKMKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLEGKQAKLKFCLDILERYVQKEK
GLKALMKGKKFMDYNELKNLGENIEWMSIYNTLREKDTKLSALKNEISKPKGEIKALEPWINFDEKISKAKFNTSTSYLG
VLPLNYKDEFRETFDSEIPVSYVETIGENKDGVYLFVVFHNDYFKEASEVLKRYGFSKIAFNYDDSPKETIKALEEEIKS
IKKEEIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAIEGWVPKDSMEELEGLIRQSEGELYYIEFN
DPLDEEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEIDPTPALVPFYLIFFGMMLSDAGYGLIMLICTLLALKTIPMEK
ATKQMIKLLYYLSYPTIVWGALYGSYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDAF
YDVGLWYITLTTAIIIVAANFGNITALNPYINPCKYIMYAGMVGLVLTQGRENKTIGAKLGAGLYGLYGITSYVGDIVSY
SRLMALGLATGFIGGAFNLMISLLGNGVKAWVFGTLIFVVGHVFNLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTPF
KPNNKYINIIKD

Specific function: Involved in ATP-driven sodium extrusion [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 74404; Mature: 74272

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIAKMKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCC
GKQAKLKFCLDILERYVQKEKGLKALMKGKKFMDYNELKNLGENIEWMSIYNTLREKDTK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
LSALKNEISKPKGEIKALEPWINFDEKISKAKFNTSTSYLGVLPLNYKDEFRETFDSEIP
HHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCC
VSYVETIGENKDGVYLFVVFHNDYFKEASEVLKRYGFSKIAFNYDDSPKETIKALEEEIK
HHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHH
SIKKEEIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAIEGWVPKDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCEEECCCEEEEECCCCCCH
MEELEGLIRQSEGELYYIEFNDPLDEEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEID
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCC
PTPALVPFYLIFFGMMLSDAGYGLIMLICTLLALKTIPMEKATKQMIKLLYYLSYPTIVW
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHH
GALYGSYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDA
HHHHHHHCCCCEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCHHHH
FYDVGLWYITLTTAIIIVAANFGNITALNPYINPCKYIMYAGMVGLVLTQGRENKTIGAK
HHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
LGAGLYGLYGITSYVGDIVSYSRLMALGLATGFIGGAFNLMISLLGNGVKAWVFGTLIFV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VGHVFNLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTPFKPNNKYINIIKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
GIAKMKKFTLLALESHKESLFEAMQKFQEVQFVNLQEEKSEKLEFMQNDSQSELVSDLE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCC
GKQAKLKFCLDILERYVQKEKGLKALMKGKKFMDYNELKNLGENIEWMSIYNTLREKDTK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHH
LSALKNEISKPKGEIKALEPWINFDEKISKAKFNTSTSYLGVLPLNYKDEFRETFDSEIP
HHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCC
VSYVETIGENKDGVYLFVVFHNDYFKEASEVLKRYGFSKIAFNYDDSPKETIKALEEEIK
HHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHH
SIKKEEIKTIEGIKVFTNKLEDLQIAYEYISLQVDREKASMNILKTDRIVAIEGWVPKDS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHCCEEECCCEEEEECCCCCCH
MEELEGLIRQSEGELYYIEFNDPLDEEEEKVPIMLKNNKIVEPFESITAMYSLPKYKEID
HHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCC
PTPALVPFYLIFFGMMLSDAGYGLIMLICTLLALKTIPMEKATKQMIKLLYYLSYPTIVW
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHH
GALYGSYFGGIINIPAIWVKPEDSVSSILIISIVFGIIHLYTGLGVKAYMLIRNKRYKDA
HHHHHHHCCCCEECCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHCCCHHHH
FYDVGLWYITLTTAIIIVAANFGNITALNPYINPCKYIMYAGMVGLVLTQGRENKTIGAK
HHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHH
LGAGLYGLYGITSYVGDIVSYSRLMALGLATGFIGGAFNLMISLLGNGVKAWVFGTLIFV
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VGHVFNLLINALGAYVHTCRLQYVEYFGKFYEGGGKPFTPFKPNNKYINIIKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8157629; 8144530 [H]