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The map label for this gene is atpA [H]

Identifier: 226950036

GI number: 226950036

Start: 2988724

End: 2990502

Strand: Reverse

Name: atpA [H]

Synonym: CLM_2989

Alternate gene names: 226950036

Gene position: 2990502-2988724 (Counterclockwise)

Preceding gene: 226950037

Following gene: 226950035

Centisome position: 71.97

GC content: 35.19

Gene sequence:

>1779_bases
GTGAACTTGAAGACAGGACGTGTTTTAAAGATATCTGGACCTTTAGTTGTTGCTGAAGGAATGGAAGAGGCAAACATATA
TGACGTTGTAAAAGTTGGTGAAAAACGTCTTATTGGTGAAATAATAGAAATGAGAGAAGATAGAGCTTCAATTCAGGTTT
ACGAAGAAACAGCAGGTTTAGCACCAGGGGATCCAGTAGTTACTACTGGAGAACCTTTAAGTGTTGAATTAGGACCTGGA
TTAATAGAAGCCATGTTTGATGGAATACAGAGACCATTAAATGTGATAAAGGATAAGGCTGGAGATTTTATAACAAAAGG
AGTAGAAGTTCATTCATTAGATAGAGATAAAAAATGGCATTTCACTCCAGTTAAAAAAGTAGGAGATACTGTTGAAGCAG
GAGATGTAATAGGTATCGTTCAAGAAACTTCTATAGTAGAACACAAAATAATGGTTCCTTATGGTATAAGAGGAACTATA
GAGACTATAGAAGAAGGAGATTTTACTATAGTTGATACTGTAGCAAAAGTTAAAGATGGAGATAAAGTTTCTGACTTAAT
GATGATGCAAAAATGGCCTGTTAGAAGGGGAAGACCTTATGGCAGAAAACTTAATCCAGCACAACCTATGATAACAGGTC
AAAGAGTTATAGATACATTCTTCCCAGTTACGAAGGGTGGTACAGCTTGTGTTCCAGGACCATTTGGAAGTGGAAAAACT
GTTGTACAACATCAATTGGCTAAATGGGCAGATGCTCAAATAGTTGTTTATATAGGTTGTGGAGAACGTGGTAATGAAAT
GACAGATGTTCTTAATGAATTCCCAGAACTAAAAGATCCTAAAACTGGTGAACCATTAATGAAAAGAACTGTACTTATAG
CCAATACTTCTAATATGCCCGTTGCAGCCAGAGAAGCTTCTATATATACTGGAATAACTATAGGAGAATATTTTAGAGAT
ATGGGATATTCTATTGCACTAATGGCAGATTCTACATCTCGTTGGGCTGAGGCGCTTCGTGAAATGTCAGGAAGACTTGA
AGAAATGCCTGGTGATGAAGGATATCCAGCATACTTAGGATCAAGAGCAGCAGAATTCTATGAAAGAGCAGGTAATGTGT
TATCTTTAGGATCTGAGGAAAGAGAAGGTGCCCTAACGGTTATAGGCGCTGTATCCCCTCCAGGAGGAGATTTATCAGAA
CCTGTTACTCAAGCTACTTTAAGAATAGTTAAAGTATTCTGGGGATTAGATGCACAACTTGCATATAGAAGACATTTTCC
AGCTATAAATTGGTTAAATTCCTATTCATTGTATATAGAAAAAATAAGCCCTTGGATGGATGAAAATGTAGCATCTGATT
GGACACAACTTAGAATTAAAGCTATGTCACTTCTCCAAGAGGAAGCTAGCTTAGAGGAAATAGTTAGACTTGTAGGTATA
GATGCTTTATCTGAAAAGGATAGATTAAAACTTGAAGTTGCAAAATCTTTAAGGGAAGATTACTTGCAACAAAATGCATT
CCATGAAGTAGACACTTATGCTTCATTGGAAAAGCAATATAAGATGTTAAAATTAGTTTTATTCTTCTATGATGAAGCTG
AAAGAGCATTAAATGCAGGAGTATATTTAAAAGAACTTTTAGATTTAGAAGTTAGAGATAAAATAGCAAGAGCAAAGTAT
GTTTCAGAGGAAAATATAAAAAATATAGATGCAATATTTAATGAATTATCAGAGGTAATAGATGAATTGATCAGCAAAGG
AGGTATAATGAATGCTTAA

Upstream 100 bases:

>100_bases
ATTCCTAGTAATCAAGGCTCTCTAAATATTGGTATGCAGAGGATAAATGATAATGTGGAAAAAGCAGTTGGCGTTAATAT
TTTATAAGGAAGGTAGGTAG

Downstream 100 bases:

>100_bases
GGAATATAGAACAGTTAAAGAAGTAGTTGGGCCACTTATGCTGGTTGATCAAGTAGAAAGCGTTAGTTTTGATGAACTTG
TTGAGATAGAACTTCACAAT

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGLAPGDPVVTTGEPLSVELGPG
LIEAMFDGIQRPLNVIKDKAGDFITKGVEVHSLDRDKKWHFTPVKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIRGTI
ETIEEGDFTIVDTVAKVKDGDKVSDLMMMQKWPVRRGRPYGRKLNPAQPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMPVAAREASIYTGITIGEYFRD
MGYSIALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRAAEFYERAGNVLSLGSEEREGALTVIGAVSPPGGDLSE
PVTQATLRIVKVFWGLDAQLAYRRHFPAINWLNSYSLYIEKISPWMDENVASDWTQLRIKAMSLLQEEASLEEIVRLVGI
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDEAERALNAGVYLKELLDLEVRDKIARAKY
VSEENIKNIDAIFNELSEVIDELISKGGIMNA

Sequences:

>Translated_592_residues
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGLAPGDPVVTTGEPLSVELGPG
LIEAMFDGIQRPLNVIKDKAGDFITKGVEVHSLDRDKKWHFTPVKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIRGTI
ETIEEGDFTIVDTVAKVKDGDKVSDLMMMQKWPVRRGRPYGRKLNPAQPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMPVAAREASIYTGITIGEYFRD
MGYSIALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRAAEFYERAGNVLSLGSEEREGALTVIGAVSPPGGDLSE
PVTQATLRIVKVFWGLDAQLAYRRHFPAINWLNSYSLYIEKISPWMDENVASDWTQLRIKAMSLLQEEASLEEIVRLVGI
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDEAERALNAGVYLKELLDLEVRDKIARAKY
VSEENIKNIDAIFNELSEVIDELISKGGIMNA
>Mature_592_residues
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGLAPGDPVVTTGEPLSVELGPG
LIEAMFDGIQRPLNVIKDKAGDFITKGVEVHSLDRDKKWHFTPVKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIRGTI
ETIEEGDFTIVDTVAKVKDGDKVSDLMMMQKWPVRRGRPYGRKLNPAQPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMPVAAREASIYTGITIGEYFRD
MGYSIALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRAAEFYERAGNVLSLGSEEREGALTVIGAVSPPGGDLSE
PVTQATLRIVKVFWGLDAQLAYRRHFPAINWLNSYSLYIEKISPWMDENVASDWTQLRIKAMSLLQEEASLEEIVRLVGI
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDEAERALNAGVYLKELLDLEVRDKIARAKY
VSEENIKNIDAIFNELSEVIDELISKGGIMNA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=538, Percent_Identity=53.9033457249071, Blast_Score=596, Evalue=1e-170,
Organism=Homo sapiens, GI32189394, Length=313, Percent_Identity=29.3929712460064, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI19913426, Length=242, Percent_Identity=28.099173553719, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI19913428, Length=242, Percent_Identity=27.2727272727273, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI50345984, Length=241, Percent_Identity=25.7261410788382, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4757810, Length=241, Percent_Identity=25.7261410788382, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1790170, Length=322, Percent_Identity=28.2608695652174, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788251, Length=318, Percent_Identity=27.3584905660377, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790172, Length=236, Percent_Identity=26.271186440678, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=540, Percent_Identity=52.5925925925926, Blast_Score=582, Evalue=1e-166,
Organism=Caenorhabditis elegans, GI25144756, Length=333, Percent_Identity=28.2282282282282, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=241, Percent_Identity=28.2157676348548, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17570191, Length=242, Percent_Identity=28.5123966942149, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988080, Length=241, Percent_Identity=26.5560165975104, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71988063, Length=241, Percent_Identity=26.5560165975104, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71988074, Length=241, Percent_Identity=26.5560165975104, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320016, Length=312, Percent_Identity=50.9615384615385, Blast_Score=329, Evalue=7e-91,
Organism=Saccharomyces cerevisiae, GI6322581, Length=336, Percent_Identity=29.1666666666667, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319603, Length=242, Percent_Identity=28.9256198347107, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319370, Length=236, Percent_Identity=26.6949152542373, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24583988, Length=541, Percent_Identity=52.8650646950092, Blast_Score=593, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24583986, Length=541, Percent_Identity=52.8650646950092, Blast_Score=593, Evalue=1e-170,
Organism=Drosophila melanogaster, GI24583984, Length=541, Percent_Identity=52.8650646950092, Blast_Score=593, Evalue=1e-170,
Organism=Drosophila melanogaster, GI20129479, Length=534, Percent_Identity=52.4344569288389, Blast_Score=587, Evalue=1e-168,
Organism=Drosophila melanogaster, GI24583992, Length=539, Percent_Identity=52.1335807050093, Blast_Score=582, Evalue=1e-166,
Organism=Drosophila melanogaster, GI28574560, Length=299, Percent_Identity=30.7692307692308, Blast_Score=119, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24638766, Length=305, Percent_Identity=29.1803278688525, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281361666, Length=242, Percent_Identity=27.6859504132231, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24646341, Length=242, Percent_Identity=27.6859504132231, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17136796, Length=242, Percent_Identity=27.6859504132231, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24658560, Length=237, Percent_Identity=26.5822784810127, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 65783; Mature: 65783

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGL
CCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCC
APGDPVVTTGEPLSVELGPGLIEAMFDGIQRPLNVIKDKAGDFITKGVEVHSLDRDKKWH
CCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCCC
FTPVKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIRGTIETIEEGDFTIVDTVAKVKDG
CCHHHHCCCCCCCCCEEEEEHHHHHHHEEEEECCCCCCCHHHHCCCCEEEEHHHHHHCCC
DKVSDLMMMQKWPVRRGRPYGRKLNPAQPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCHH
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMP
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEEECCCCC
VAAREASIYTGITIGEYFRDMGYSIALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLG
EEECCCCEEECCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
SRAAEFYERAGNVLSLGSEEREGALTVIGAVSPPGGDLSEPVTQATLRIVKVFWGLDAQL
HHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
AYRRHFPAINWLNSYSLYIEKISPWMDENVASDWTQLRIKAMSLLQEEASLEEIVRLVGI
HHHHCCCCHHHHCCHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDEAERALNAG
HHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VYLKELLDLEVRDKIARAKYVSEENIKNIDAIFNELSEVIDELISKGGIMNA
HHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNLKTGRVLKISGPLVVAEGMEEANIYDVVKVGEKRLIGEIIEMREDRASIQVYEETAGL
CCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHCCC
APGDPVVTTGEPLSVELGPGLIEAMFDGIQRPLNVIKDKAGDFITKGVEVHSLDRDKKWH
CCCCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCCC
FTPVKKVGDTVEAGDVIGIVQETSIVEHKIMVPYGIRGTIETIEEGDFTIVDTVAKVKDG
CCHHHHCCCCCCCCCEEEEEHHHHHHHEEEEECCCCCCCHHHHCCCCEEEEHHHHHHCCC
DKVSDLMMMQKWPVRRGRPYGRKLNPAQPMITGQRVIDTFFPVTKGGTACVPGPFGSGKT
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECCCCCCCCHH
VVQHQLAKWADAQIVVYIGCGERGNEMTDVLNEFPELKDPKTGEPLMKRTVLIANTSNMP
HHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCHHHHCEEEEEECCCCC
VAAREASIYTGITIGEYFRDMGYSIALMADSTSRWAEALREMSGRLEEMPGDEGYPAYLG
EEECCCCEEECCHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
SRAAEFYERAGNVLSLGSEEREGALTVIGAVSPPGGDLSEPVTQATLRIVKVFWGLDAQL
HHHHHHHHHCCCEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCHHH
AYRRHFPAINWLNSYSLYIEKISPWMDENVASDWTQLRIKAMSLLQEEASLEEIVRLVGI
HHHHCCCCHHHHCCHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DALSEKDRLKLEVAKSLREDYLQQNAFHEVDTYASLEKQYKMLKLVLFFYDEAERALNAG
HHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VYLKELLDLEVRDKIARAKYVSEENIKNIDAIFNELSEVIDELISKGGIMNA
HHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA