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The map label for this gene is fabH [H]

Identifier: 226949940

GI number: 226949940

Start: 2903529

End: 2904539

Strand: Reverse

Name: fabH [H]

Synonym: CLM_2892

Alternate gene names: 226949940

Gene position: 2904539-2903529 (Counterclockwise)

Preceding gene: 226949941

Following gene: 226949939

Centisome position: 69.9

GC content: 34.03

Gene sequence:

>1011_bases
ATGAGATCAAGGATTAAGGGAGTAGGAAGATACTTACCAAATAGAATTGTAACTAGCGAGGAAGCAGAAGAACTTGCAGG
TTTTAAAAAATTGGGAGTTAGAAAAGGACTTTGTAAGATGCTAACGGGATGTGAAGAAAGAAGATATTCAGATACCAATG
AATATAGTTCACATATTGCAGCGAAGGCAGCCATAGATGCCATGAAAAAGGCAGGAGTTTCAAGTGATGAAGTTGATGCA
CTTATTTTTTGTTCTGTATCTCAAGATTTTGCTGAACCAGCAACAGCAAATGTAGTGATGGATTTATTGAACATAAAGAA
TGCATTTGGATTTGATGTTAAAAATGCTTGCAATGCATTCTTAACAGGTATTGATATTGCAGATAGTTTAATAAAGACAG
GAAAAGCTGATATAGTTCTTGTTGTTTCTGGAGAAGCTTTATCAAAATGGATCAATTTTAAGTTTGAATCTAAAGAGGAA
CTAATTAGAAGAGCTCCAGTGACTTTGTCTATAGGCGATGGTGGTGGCGCTTTTATAATGGAAAGAGAGGAAGATGACAA
TAAAGGCATTGTGAAAAGTATTTTTCGTACATATGCAGAATATTGGAACAATAATGTAGTTTGGGGAGGTGGAGTTCGTT
TCCCGAGAGATTCTGATAAAATGTATATTCCTGGGACTACTAAAGTTATAATAGATGAACAAAGAAATTTAGGGAAAAAC
TTATTGCCAATTTTAGAACGTGAAGTTGGGTGGAATTTTCAGAAGGATGTAGATTGTTATATCCCAACACAAGTAGCTAA
ATGGATTAATAAGAGTATGTCTAACGAATTATCTTTCCCAATTGAAAAAATTATTCAGGTTATTGATAAATTTGGAAATG
TTGGAGCTAGTAATATTCCAATAGCAACATATGAAGCTATTATGGATGGAAGATTAAAGACTGGAAGTAAAACCTTAATG
TCTGGTGTTGGAGTTGGAATTAATATTGCGACTATCGCAGTAATACTTTAG

Upstream 100 bases:

>100_bases
TAGAAGGAGATCATTTGATTCTATTTAATAATAATGAAACTGTATTACAAAAGATACAGGAAAAAGCAGAAACTATATTT
AAAAAAATTTGAGGTGAATT

Downstream 100 bases:

>100_bases
TTATGTAGGTGAGTATATGAAAGAAAAGGTTACTTTTGGAGATATATATACTGTAATTTTTCAAGAGGAAGATAGTAATA
AAGAATGTATAATAGTCTAC

Product: putative 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MRSRIKGVGRYLPNRIVTSEEAEELAGFKKLGVRKGLCKMLTGCEERRYSDTNEYSSHIAAKAAIDAMKKAGVSSDEVDA
LIFCSVSQDFAEPATANVVMDLLNIKNAFGFDVKNACNAFLTGIDIADSLIKTGKADIVLVVSGEALSKWINFKFESKEE
LIRRAPVTLSIGDGGGAFIMEREEDDNKGIVKSIFRTYAEYWNNNVVWGGGVRFPRDSDKMYIPGTTKVIIDEQRNLGKN
LLPILEREVGWNFQKDVDCYIPTQVAKWINKSMSNELSFPIEKIIQVIDKFGNVGASNIPIATYEAIMDGRLKTGSKTLM
SGVGVGINIATIAVIL

Sequences:

>Translated_336_residues
MRSRIKGVGRYLPNRIVTSEEAEELAGFKKLGVRKGLCKMLTGCEERRYSDTNEYSSHIAAKAAIDAMKKAGVSSDEVDA
LIFCSVSQDFAEPATANVVMDLLNIKNAFGFDVKNACNAFLTGIDIADSLIKTGKADIVLVVSGEALSKWINFKFESKEE
LIRRAPVTLSIGDGGGAFIMEREEDDNKGIVKSIFRTYAEYWNNNVVWGGGVRFPRDSDKMYIPGTTKVIIDEQRNLGKN
LLPILEREVGWNFQKDVDCYIPTQVAKWINKSMSNELSFPIEKIIQVIDKFGNVGASNIPIATYEAIMDGRLKTGSKTLM
SGVGVGINIATIAVIL
>Mature_336_residues
MRSRIKGVGRYLPNRIVTSEEAEELAGFKKLGVRKGLCKMLTGCEERRYSDTNEYSSHIAAKAAIDAMKKAGVSSDEVDA
LIFCSVSQDFAEPATANVVMDLLNIKNAFGFDVKNACNAFLTGIDIADSLIKTGKADIVLVVSGEALSKWINFKFESKEE
LIRRAPVTLSIGDGGGAFIMEREEDDNKGIVKSIFRTYAEYWNNNVVWGGGVRFPRDSDKMYIPGTTKVIIDEQRNLGKN
LLPILEREVGWNFQKDVDCYIPTQVAKWINKSMSNELSFPIEKIIQVIDKFGNVGASNIPIATYEAIMDGRLKTGSKTLM
SGVGVGINIATIAVIL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=332, Percent_Identity=25.3012048192771, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 36984; Mature: 36984

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRIKGVGRYLPNRIVTSEEAEELAGFKKLGVRKGLCKMLTGCEERRYSDTNEYSSHIA
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AKAAIDAMKKAGVSSDEVDALIFCSVSQDFAEPATANVVMDLLNIKNAFGFDVKNACNAF
HHHHHHHHHHCCCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
LTGIDIADSLIKTGKADIVLVVSGEALSKWINFKFESKEELIRRAPVTLSIGDGGGAFIM
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCEEEE
EREEDDNKGIVKSIFRTYAEYWNNNVVWGGGVRFPRDSDKMYIPGTTKVIIDEQRNLGKN
ECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEECCCCEEEEEECCCCCCCH
LLPILEREVGWNFQKDVDCYIPTQVAKWINKSMSNELSFPIEKIIQVIDKFGNVGASNIP
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
IATYEAIMDGRLKTGSKTLMSGVGVGINIATIAVIL
HHHHHHHHCCCCCCCHHHHHHHCCCCEEHHHEEEEC
>Mature Secondary Structure
MRSRIKGVGRYLPNRIVTSEEAEELAGFKKLGVRKGLCKMLTGCEERRYSDTNEYSSHIA
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AKAAIDAMKKAGVSSDEVDALIFCSVSQDFAEPATANVVMDLLNIKNAFGFDVKNACNAF
HHHHHHHHHHCCCCCCCCCEEEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
LTGIDIADSLIKTGKADIVLVVSGEALSKWINFKFESKEELIRRAPVTLSIGDGGGAFIM
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCCHHHHHHHCCCEEEECCCCCEEEE
EREEDDNKGIVKSIFRTYAEYWNNNVVWGGGVRFPRDSDKMYIPGTTKVIIDEQRNLGKN
ECCCCCCCHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCEECCCCEEEEEECCCCCCCH
LLPILEREVGWNFQKDVDCYIPTQVAKWINKSMSNELSFPIEKIIQVIDKFGNVGASNIP
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCC
IATYEAIMDGRLKTGSKTLMSGVGVGINIATIAVIL
HHHHHHHHCCCCCCCHHHHHHHCCCCEEHHHEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA