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The map label for this gene is frr [H]

Identifier: 226949785

GI number: 226949785

Start: 2739174

End: 2739728

Strand: Reverse

Name: frr [H]

Synonym: CLM_2725

Alternate gene names: 226949785

Gene position: 2739728-2739174 (Counterclockwise)

Preceding gene: 226949786

Following gene: 226949784

Centisome position: 65.93

GC content: 28.29

Gene sequence:

>555_bases
GTGATAAAAGAAATATTAAAAAAAGCAGATGAAAAAATGGGTAAAACTATTGTAGCTTTAAAAAGAGAATTAGCTTCAAT
GAAAGCTGGTAGAGCTAATCCAGCTATGCTTGATAGAATAGAAGCAGAATATTATGGTTCTATGACTCCACTAAATCAAT
TAGGAAATATATCTGTACCAGAAGCAAGGGTTCTTTTAATACAACCTTGGGATAAAAGTGCTTTATCAGCTATAGAGAAA
GCTATATTAAAATCAGATTTAGGCTTAAATCCTTCTAATGATGGTACTGTAATAAGACTTGTTATACCAGAATTAACAGA
AGAAACAAGAAAAAACATAGTTAAAACTGTGAAAAAAACTGGAGAGGAAGCAAAAGTAGCTATAAGATCTATAAGAAGAG
ATTGTAATGATGATGTTAAGAATCTAAAAAAAGATGACGTTTCAGAAGATGATATTAAAAAAGCAGAAGATGATATCCAA
AAGAAAACAGATAAATATATAAAAGAAATAGATTCTATAATAAGTGCAAAAGAAAAGGAAATACTATCTATATAA

Upstream 100 bases:

>100_bases
AGTTTTTGGATTAGATGAACCTTGCAATATAATAAAAGCTGTAACTGGAGAAGAAATAGGTACTCTAGTTTCAAATTCAA
AATAAGGGGAGGTTATTTAA

Downstream 100 bases:

>100_bases
ACATTATAACCTGCTTATTAGCAGGTTTTTTAATAATTTAGAGTAAATATGTTGGGGGTAACTTTATGAAAAATTTTTTT
TCAAGTAACAAAAAAGCTAG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MIKEILKKADEKMGKTIVALKRELASMKAGRANPAMLDRIEAEYYGSMTPLNQLGNISVPEARVLLIQPWDKSALSAIEK
AILKSDLGLNPSNDGTVIRLVIPELTEETRKNIVKTVKKTGEEAKVAIRSIRRDCNDDVKNLKKDDVSEDDIKKAEDDIQ
KKTDKYIKEIDSIISAKEKEILSI

Sequences:

>Translated_184_residues
MIKEILKKADEKMGKTIVALKRELASMKAGRANPAMLDRIEAEYYGSMTPLNQLGNISVPEARVLLIQPWDKSALSAIEK
AILKSDLGLNPSNDGTVIRLVIPELTEETRKNIVKTVKKTGEEAKVAIRSIRRDCNDDVKNLKKDDVSEDDIKKAEDDIQ
KKTDKYIKEIDSIISAKEKEILSI
>Mature_184_residues
MIKEILKKADEKMGKTIVALKRELASMKAGRANPAMLDRIEAEYYGSMTPLNQLGNISVPEARVLLIQPWDKSALSAIEK
AILKSDLGLNPSNDGTVIRLVIPELTEETRKNIVKTVKKTGEEAKVAIRSIRRDCNDDVKNLKKDDVSEDDIKKAEDDIQ
KKTDKYIKEIDSIISAKEKEILSI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=33.5195530726257, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI291042689, Length=163, Percent_Identity=33.7423312883436, Blast_Score=78, Evalue=5e-15,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=46.4864864864865, Blast_Score=173, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24661488, Length=186, Percent_Identity=26.8817204301075, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20605; Mature: 20605

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKEILKKADEKMGKTIVALKRELASMKAGRANPAMLDRIEAEYYGSMTPLNQLGNISVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCC
EARVLLIQPWDKSALSAIEKAILKSDLGLNPSNDGTVIRLVIPELTEETRKNIVKTVKKT
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHC
GEEAKVAIRSIRRDCNDDVKNLKKDDVSEDDIKKAEDDIQKKTDKYIKEIDSIISAKEKE
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSI
HHCC
>Mature Secondary Structure
MIKEILKKADEKMGKTIVALKRELASMKAGRANPAMLDRIEAEYYGSMTPLNQLGNISVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCC
EARVLLIQPWDKSALSAIEKAILKSDLGLNPSNDGTVIRLVIPELTEETRKNIVKTVKKT
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHC
GEEAKVAIRSIRRDCNDDVKNLKKDDVSEDDIKKAEDDIQKKTDKYIKEIDSIISAKEKE
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA