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The map label for this gene is msrB [H]

Identifier: 226949646

GI number: 226949646

Start: 2616125

End: 2616574

Strand: Reverse

Name: msrB [H]

Synonym: CLM_2583

Alternate gene names: 226949646

Gene position: 2616574-2616125 (Counterclockwise)

Preceding gene: 226949647

Following gene: 226949645

Centisome position: 62.97

GC content: 30.44

Gene sequence:

>450_bases
ATGAATAAAAATTATAGTAAAAAGCCTAAAGAGGAATTAAAAAAGATACTAACACCAGAGGAGTATTATGTTACTCAAGA
AAATGGAACGGAAGCACCATATAAAAATGAGTATTGGAATTTAAATGAAGAAGGAATTTATGTAGATATAACCAATGGAG
AGCCCTTATTTACTTCAAAAGATAAGTTTAATTCTTCATGTGGATGGCCAGCATTTAGCAAGCCTATAGATAGAAAAATA
ATAAAAGAATCTATTGATAAAAGTCATGGAATGACTAGAACAGAAGTAAGAAGTAAAAATGCTGATTCTCATTTAGGTCA
TGTATTTTGTGACGGACCAGAAGAGTTAGGTGGATTAAGATATTGTATTAATTCAGCTTCACTTAAATTTATCCCCAAGA
ACGAGCTTGAAGAAGAAGGGTATGGTGAGTATTTAAAGTTGTTTAAATAA

Upstream 100 bases:

>100_bases
TAAGGCATATTATTATTTTTACTTTATAATAATATATTAAGACATTTATTTAAAGTTTATATAGATTAATCTTATAAAAA
ATTTAAATCAAGGAGGAAAT

Downstream 100 bases:

>100_bases
TAGTAATAAATTTTATTAATAATTTAAATCAAAATTTTTATTATGAAATTGAAAAAAATAGAGATGACTAGGAAAAATAA
GTCATATAATATCTAAAAAT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MNKNYSKKPKEELKKILTPEEYYVTQENGTEAPYKNEYWNLNEEGIYVDITNGEPLFTSKDKFNSSCGWPAFSKPIDRKI
IKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEELGGLRYCINSASLKFIPKNELEEEGYGEYLKLFK

Sequences:

>Translated_149_residues
MNKNYSKKPKEELKKILTPEEYYVTQENGTEAPYKNEYWNLNEEGIYVDITNGEPLFTSKDKFNSSCGWPAFSKPIDRKI
IKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEELGGLRYCINSASLKFIPKNELEEEGYGEYLKLFK
>Mature_149_residues
MNKNYSKKPKEELKKILTPEEYYVTQENGTEAPYKNEYWNLNEEGIYVDITNGEPLFTSKDKFNSSCGWPAFSKPIDRKI
IKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEELGGLRYCINSASLKFIPKNELEEEGYGEYLKLFK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=46.4, Blast_Score=119, Evalue=7e-28,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=46.4, Blast_Score=119, Evalue=7e-28,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=46.4, Blast_Score=119, Evalue=7e-28,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=46.4, Blast_Score=119, Evalue=9e-28,
Organism=Homo sapiens, GI117606353, Length=131, Percent_Identity=45.8015267175573, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI1788077, Length=125, Percent_Identity=47.2, Blast_Score=124, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI115532676, Length=136, Percent_Identity=46.3235294117647, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17553450, Length=136, Percent_Identity=46.3235294117647, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=137, Percent_Identity=36.4963503649635, Blast_Score=80, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221378664, Length=123, Percent_Identity=47.9674796747967, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI221378662, Length=130, Percent_Identity=46.1538461538462, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24645799, Length=123, Percent_Identity=47.1544715447154, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI45553335, Length=123, Percent_Identity=47.1544715447154, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI21356369, Length=123, Percent_Identity=47.1544715447154, Blast_Score=109, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24645801, Length=134, Percent_Identity=44.0298507462687, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24645804, Length=134, Percent_Identity=44.0298507462687, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 17198; Mature: 17198

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNYSKKPKEELKKILTPEEYYVTQENGTEAPYKNEYWNLNEEGIYVDITNGEPLFTSK
CCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
DKFNSSCGWPAFSKPIDRKIIKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEELGGLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEECCHHHHCHHH
YCINSASLKFIPKNELEEEGYGEYLKLFK
HHHCCCCEEECCCCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MNKNYSKKPKEELKKILTPEEYYVTQENGTEAPYKNEYWNLNEEGIYVDITNGEPLFTSK
CCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCC
DKFNSSCGWPAFSKPIDRKIIKESIDKSHGMTRTEVRSKNADSHLGHVFCDGPEELGGLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEECCHHHHCHHH
YCINSASLKFIPKNELEEEGYGEYLKLFK
HHHCCCCEEECCCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA