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The map label for this gene is xerD [H]

Identifier: 226949603

GI number: 226949603

Start: 2594933

End: 2595928

Strand: Reverse

Name: xerD [H]

Synonym: CLM_2540

Alternate gene names: 226949603

Gene position: 2595928-2594933 (Counterclockwise)

Preceding gene: 226949604

Following gene: 226949602

Centisome position: 62.47

GC content: 31.22

Gene sequence:

>996_bases
ATGTATAGTACAAGTGCAAAGAATGAAGTTGTAATTAAATTAGTAGGCAAGTTGTCTATGGAATTTGAGGGAATAGACCA
GTTAAAGGTTAGAAGCATAGTAGAGGAAGTTTTATATAAATACAATATATTGCCAGAGGAGACAGGCTTAGTAACAAGCG
ATATAGAAGAGAAATTACAAATATACTTAGCATCTAAAAAATTGGATGGTTTAAGTATAGAAACATTAAAAAATTACAGA
TATAACTTAATAATATTTGCAGATTATTTAAGAAAACCTTTAGCAGCTATAGAAACAATGGATTTAAGAATGTTTTTAGG
GGCTAGATGCAAGGATATGAAGCAAAGTAGTGTTAACGGACAAATATCAATTCTAAAAAGCTTCTTTGGTTGGCTTGCGG
ATGAGGAGTATATACCTAAAAATCCAGCTAAAAAGTTGAAGCAAACTAAACAGCCTAAAAGAGTTAGGAAGCCATTAACA
GAGGAAGAGGCTGAATTATTAAGACAAGCTTGCGAAACGGACAGACAAAAGGCATTGACAGAGTTCTTAATATCTACAGG
ATGCAGACTGGATGAAGTTTTTAAAGTAAATAAAGACGATATTAATTGGCACGAAATGAGCCTATTTATAGTTGGTAAAG
GAGATAAGGAACGAAAAGTTTACTTTAATACAAAAGCTAAAATTTTATTAAAAAAATATTTATTTTCAAGGGAAGATGAT
AATCCAGCATTATTCGTTACATCCAAAAGACCTTATCATAGATTAGGAAAAAGGAGTATTCAAAGAGAATTTAAAAAGAT
AGCGAATATAGCAGGAATAGAAAAGTCAATACATCCTCACTTATTTAGACACTCTTTTGCAACCTACAAGATTAATAGTG
GTATGCCAATGCCAATTATACAACACTTAATGGGACATGAAAGCCCAGCAACTACTCAAATATATGCTCAACTATCAGAA
GAAACCGTAAAATATGAATACAAAAAAATATCTTAA

Upstream 100 bases:

>100_bases
TAAATATAGTAAATAGATTTTCAATTTAGGAGGATTAAATATTAAATCATAATTCTATCAAAATTAAAATGTCTTTAATG
GCAATATAGGAGGTATTTAT

Downstream 100 bases:

>100_bases
TAAGAAGGTGAAATATATGCGTAGACTTTCAATGATGGGATCATCTAAATATGAATTTAATCCAGAGCAGTTTAATGAAG
ATGTTAAAAAGCATAGAGAA

Product: phage integrase family site-specific recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MYSTSAKNEVVIKLVGKLSMEFEGIDQLKVRSIVEEVLYKYNILPEETGLVTSDIEEKLQIYLASKKLDGLSIETLKNYR
YNLIIFADYLRKPLAAIETMDLRMFLGARCKDMKQSSVNGQISILKSFFGWLADEEYIPKNPAKKLKQTKQPKRVRKPLT
EEEAELLRQACETDRQKALTEFLISTGCRLDEVFKVNKDDINWHEMSLFIVGKGDKERKVYFNTKAKILLKKYLFSREDD
NPALFVTSKRPYHRLGKRSIQREFKKIANIAGIEKSIHPHLFRHSFATYKINSGMPMPIIQHLMGHESPATTQIYAQLSE
ETVKYEYKKIS

Sequences:

>Translated_331_residues
MYSTSAKNEVVIKLVGKLSMEFEGIDQLKVRSIVEEVLYKYNILPEETGLVTSDIEEKLQIYLASKKLDGLSIETLKNYR
YNLIIFADYLRKPLAAIETMDLRMFLGARCKDMKQSSVNGQISILKSFFGWLADEEYIPKNPAKKLKQTKQPKRVRKPLT
EEEAELLRQACETDRQKALTEFLISTGCRLDEVFKVNKDDINWHEMSLFIVGKGDKERKVYFNTKAKILLKKYLFSREDD
NPALFVTSKRPYHRLGKRSIQREFKKIANIAGIEKSIHPHLFRHSFATYKINSGMPMPIIQHLMGHESPATTQIYAQLSE
ETVKYEYKKIS
>Mature_331_residues
MYSTSAKNEVVIKLVGKLSMEFEGIDQLKVRSIVEEVLYKYNILPEETGLVTSDIEEKLQIYLASKKLDGLSIETLKNYR
YNLIIFADYLRKPLAAIETMDLRMFLGARCKDMKQSSVNGQISILKSFFGWLADEEYIPKNPAKKLKQTKQPKRVRKPLT
EEEAELLRQACETDRQKALTEFLISTGCRLDEVFKVNKDDINWHEMSLFIVGKGDKERKVYFNTKAKILLKKYLFSREDD
NPALFVTSKRPYHRLGKRSIQREFKKIANIAGIEKSIHPHLFRHSFATYKINSGMPMPIIQHLMGHESPATTQIYAQLSE
ETVKYEYKKIS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=286, Percent_Identity=30.0699300699301, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790244, Length=291, Percent_Identity=29.2096219931272, Blast_Score=114, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38432; Mature: 38432

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSTSAKNEVVIKLVGKLSMEFEGIDQLKVRSIVEEVLYKYNILPEETGLVTSDIEEKLQ
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
IYLASKKLDGLSIETLKNYRYNLIIFADYLRKPLAAIETMDLRMFLGARCKDMKQSSVNG
HHHHHCCCCCCCHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
QISILKSFFGWLADEEYIPKNPAKKLKQTKQPKRVRKPLTEEEAELLRQACETDRQKALT
HHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EFLISTGCRLDEVFKVNKDDINWHEMSLFIVGKGDKERKVYFNTKAKILLKKYLFSREDD
HHHHHCCCCHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCC
NPALFVTSKRPYHRLGKRSIQREFKKIANIAGIEKSIHPHLFRHSFATYKINSGMPMPII
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHH
QHLMGHESPATTQIYAQLSEETVKYEYKKIS
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYSTSAKNEVVIKLVGKLSMEFEGIDQLKVRSIVEEVLYKYNILPEETGLVTSDIEEKLQ
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
IYLASKKLDGLSIETLKNYRYNLIIFADYLRKPLAAIETMDLRMFLGARCKDMKQSSVNG
HHHHHCCCCCCCHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
QISILKSFFGWLADEEYIPKNPAKKLKQTKQPKRVRKPLTEEEAELLRQACETDRQKALT
HHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHH
EFLISTGCRLDEVFKVNKDDINWHEMSLFIVGKGDKERKVYFNTKAKILLKKYLFSREDD
HHHHHCCCCHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHCCCCC
NPALFVTSKRPYHRLGKRSIQREFKKIANIAGIEKSIHPHLFRHSFATYKINSGMPMPII
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHH
QHLMGHESPATTQIYAQLSEETVKYEYKKIS
HHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]