Click here to switch to the map view.

The map label for this gene is mjaIIIM [H]

Identifier: 226949601

GI number: 226949601

Start: 2593859

End: 2594686

Strand: Reverse

Name: mjaIIIM [H]

Synonym: CLM_2538

Alternate gene names: 226949601

Gene position: 2594686-2593859 (Counterclockwise)

Preceding gene: 226949602

Following gene: 226949600

Centisome position: 62.44

GC content: 31.16

Gene sequence:

>828_bases
ATGAAGCTTAAACATATAAGCAATATAAAGTGGATAGGTGGCAAACATGGCAAAGAGGAAAAGTACCTGGATTTAATGCC
AGAACATAAAATATTCGTGGATTGTTTCTTTGGATCCGGAGCAATACCTTTTTATAAAGAAACAGTAAAACCAGCAAAAC
TTACAGTAGTAAATGATATTAATGATAGATTAATAAATTATATGATGGTACTTAAAGAGGATCCCGAAAGGCTATATAAA
GAATGTAGCTCATTACCTTATAGTGAGAGCTTGTTTGAAAAATGGAAATGGGAAGCATGGCCGGAAGATAATTTACAAGC
GGCAGTAAGATTTTATTACCTTATGAGAGTTTGTTTTGGTGGTGGGGGTCACAAATACAGAAACGGAATAGGATTGTCTA
AAACTCAAAATAAGGCTAAGCAATTAATGACAGCCACAGAATTAATTCCTAAGATGGCTGGACTAATAAAAGAGTGGAAT
ATTTTAAATAGAGATTTTGAGGAAGTAATAAAATTTTATGATACAGAAGAAACATTATTTTTCTTAGATCCACCATATCA
TAAGCATGAAGATATGTACTTTGGAGGATTTGAAGAAAAGGACCATATAAGATTAAAGAAAAGATTAGATAAGATAAAAG
GAAAAGCTATGGTTTGTTATTATAGTAGTCCATTAATAGATGAATTATATAAAGATTGGCATATAGTTGAATATAGTACG
GCCAGCCAAATAAAAAATAGAATTGATGGGGAAAAGTGTCCAGTAAGAAATGAATTGATACTTATGAATTATAAACCTAT
AGGGTTTGAACAATTAAGCATTGTTTAG

Upstream 100 bases:

>100_bases
TTATAAATCAAGATACTTATCAGGATAGAAATTTTAGAATAATAACAAAGGTTTTAAAAATGCTTAAAATTAGGTATGAC
TTATAAATAGAGGTGATAAA

Downstream 100 bases:

>100_bases
ATCAGAGAGGAGTAAAAGTAATGGCTAAAAGAGATAATGTTTATTTAGTATTAATGACACATTGTAATGTTAATTTGCAA
TGTGATGATAAAAAGCTCCA

Product: D12 class N6 adenine-specific DNA methyltransferase superfamily protein

Products: NA

Alternate protein names: M.MjaIII; Adenine-specific methyltransferase MjaIII [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKLKHISNIKWIGGKHGKEEKYLDLMPEHKIFVDCFFGSGAIPFYKETVKPAKLTVVNDINDRLINYMMVLKEDPERLYK
ECSSLPYSESLFEKWKWEAWPEDNLQAAVRFYYLMRVCFGGGGHKYRNGIGLSKTQNKAKQLMTATELIPKMAGLIKEWN
ILNRDFEEVIKFYDTEETLFFLDPPYHKHEDMYFGGFEEKDHIRLKKRLDKIKGKAMVCYYSSPLIDELYKDWHIVEYST
ASQIKNRIDGEKCPVRNELILMNYKPIGFEQLSIV

Sequences:

>Translated_275_residues
MKLKHISNIKWIGGKHGKEEKYLDLMPEHKIFVDCFFGSGAIPFYKETVKPAKLTVVNDINDRLINYMMVLKEDPERLYK
ECSSLPYSESLFEKWKWEAWPEDNLQAAVRFYYLMRVCFGGGGHKYRNGIGLSKTQNKAKQLMTATELIPKMAGLIKEWN
ILNRDFEEVIKFYDTEETLFFLDPPYHKHEDMYFGGFEEKDHIRLKKRLDKIKGKAMVCYYSSPLIDELYKDWHIVEYST
ASQIKNRIDGEKCPVRNELILMNYKPIGFEQLSIV
>Mature_275_residues
MKLKHISNIKWIGGKHGKEEKYLDLMPEHKIFVDCFFGSGAIPFYKETVKPAKLTVVNDINDRLINYMMVLKEDPERLYK
ECSSLPYSESLFEKWKWEAWPEDNLQAAVRFYYLMRVCFGGGGHKYRNGIGLSKTQNKAKQLMTATELIPKMAGLIKEWN
ILNRDFEEVIKFYDTEETLFFLDPPYHKHEDMYFGGFEEKDHIRLKKRLDKIKGKAMVCYYSSPLIDELYKDWHIVEYST
ASQIKNRIDGEKCPVRNELILMNYKPIGFEQLSIV

Specific function: This methylase recognizes the double-stranded sequence GATC, causes specific methylation on A-2 on both strands, and protects the DNA from cleavage by the MjaIII endonuclease (Potential) [H]

COG id: COG0338

COG function: function code L; Site-specific DNA methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023095
- InterPro:   IPR002052
- InterPro:   IPR012327 [H]

Pfam domain/function: PF02086 MethyltransfD12 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 32454; Mature: 32454

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKHISNIKWIGGKHGKEEKYLDLMPEHKIFVDCFFGSGAIPFYKETVKPAKLTVVNDI
CCCCCCCCEEEECCCCCCCCHHHHCCCCCEEEEEEEECCCCCCHHHHCCCCEEEEEECCH
NDRLINYMMVLKEDPERLYKECSSLPYSESLFEKWKWEAWPEDNLQAAVRFYYLMRVCFG
HHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC
GGGHKYRNGIGLSKTQNKAKQLMTATELIPKMAGLIKEWNILNRDFEEVIKFYDTEETLF
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
FLDPPYHKHEDMYFGGFEEKDHIRLKKRLDKIKGKAMVCYYSSPLIDELYKDWHIVEYST
EECCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCEEEEECH
ASQIKNRIDGEKCPVRNELILMNYKPIGFEQLSIV
HHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEECC
>Mature Secondary Structure
MKLKHISNIKWIGGKHGKEEKYLDLMPEHKIFVDCFFGSGAIPFYKETVKPAKLTVVNDI
CCCCCCCCEEEECCCCCCCCHHHHCCCCCEEEEEEEECCCCCCHHHHCCCCEEEEEECCH
NDRLINYMMVLKEDPERLYKECSSLPYSESLFEKWKWEAWPEDNLQAAVRFYYLMRVCFG
HHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHC
GGGHKYRNGIGLSKTQNKAKQLMTATELIPKMAGLIKEWNILNRDFEEVIKFYDTEETLF
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
FLDPPYHKHEDMYFGGFEEKDHIRLKKRLDKIKGKAMVCYYSSPLIDELYKDWHIVEYST
EECCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCCEEEEECH
ASQIKNRIDGEKCPVRNELILMNYKPIGFEQLSIV
HHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]