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The map label for this gene is gntP [C]

Identifier: 226949475

GI number: 226949475

Start: 2489455

End: 2490843

Strand: Reverse

Name: gntP [C]

Synonym: CLM_2408

Alternate gene names: 226949475

Gene position: 2490843-2489455 (Counterclockwise)

Preceding gene: 226949476

Following gene: 226949473

Centisome position: 59.94

GC content: 32.9

Gene sequence:

>1389_bases
ATGGGAAACACAGTAGCAGGAAATCAAATGATATTAGGACTTGTAGTTGGAATCAGCATACTTGTATTTTTAATATTAAA
AACTAAAATTCATACATTTTTAGCACTAATTATTGCAGCAGCTACTACTGGACTTGTAGGAGGAATGCCACCTAATAAAA
TAATTGATTCAATATCTAAGGGTTTTGGGGGAACATTAGGAAGCATTGGTATAATCATAGGTTTTGGGGTAATGATGGGC
CAGATTTTTGAAGTATCTGGTGCAGCGGAGAGAATGGCTAGAACTTTTATAAAGTTCTTAGGTAAAAAAAGAGAAGAATT
AGCATTAGCAATAACAGGGTTTATAGTGTCTATACCTATATTTTGTGATTCAGGATTTATAATTTTAGCACCACTTGCAA
AAGCAATTTCCAAGAAAACTAAAAAATCAGTAGTTTCTCTAGGAGTAGCTTTAGGATTAGGACTTGTAATTACACATAGT
TTGGTACCACCAACACCTGGCCCAGTAGGAGTTGCAGGGATATTTGGAGTAAGTGTAGGGAACTTTATTTTATGGGGAAT
TCCTTTAGCTATACCTATGGTGATAGCCGGAATGATTTATGGAAAGTATATAGGAAAAAAAATATATCAAATTCCAGGGG
ATAAAGAAGATGAGTGGATTAGAACAGAATATCAAGAGCCAGTATATGATTTTGAACATGAAGAGGATAATAAAGAACTA
CCATCTACATTTATGGCTTTTGCACCAATAATAACACCTATAATATTTATACTTATAAATACTATATTAGATGTTTTAAT
TAAACAAAAGACAATAACTCCTAGTGGATTTACTAATATGATTCAATTTTTAGGTTCTCCAATAATTGCTGTTGGAATTG
GTCTTGTAATTGCTATATATGGACTAGCGGGTAAGCTAAATAAAGAAGAAGTTATAAATGAAATGGAAAAAGGAATAAAA
TCTGCTGGTATAATAATATTAGTTACCGGTGGAGGTGGAGCATTAGGTATGGTGCTTCGTGATAGTGGTACAGGAGATTA
TATAGCAAAATTAATCGCAGGTTCTCATATGCCTGTTGTATTAATACCTTTTATAATAGCATCTTTAGTAAGACTTATTC
AAGGAAGTGGAACAGTTGCCATGATAACTGCAGCTTCTATAACTGCACCAATTGTTGCAGCATCAAATGTTAATCCAATA
TTAGCAGCCCTTGGAGCATGTATGGGATCACTTTTATTCTCATATTTCAATGATAGTTATTTCTGGGTAGTTAATCGTTC
CCTTGGAATAAAAGACGCAAAAGAACAAATAAAAGTATGGTCAGTTACTACTACTATAGCTTGGGCAGTAGGTTTAATAG
AACTAATTATATTAAGTTTTATACTATAA

Upstream 100 bases:

>100_bases
ATTACATAAATTTATTACATAGATAAAGTATACATAAAATTTTTTACTAGTTTTTTTAAACACAAATGAATACCTTTACA
AAACAAAAGGAGGAAGAATA

Downstream 100 bases:

>100_bases
AATGTAAATGAATCCAGCTGAAGTTTTTATTTCAGCTGAATTTTACTTTAATAAAATTAGGCTATGTTTTAGAATAATGT
TGATAATATATCAATTTTTA

Product: gluconate permease

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MGNTVAGNQMILGLVVGISILVFLILKTKIHTFLALIIAAATTGLVGGMPPNKIIDSISKGFGGTLGSIGIIIGFGVMMG
QIFEVSGAAERMARTFIKFLGKKREELALAITGFIVSIPIFCDSGFIILAPLAKAISKKTKKSVVSLGVALGLGLVITHS
LVPPTPGPVGVAGIFGVSVGNFILWGIPLAIPMVIAGMIYGKYIGKKIYQIPGDKEDEWIRTEYQEPVYDFEHEEDNKEL
PSTFMAFAPIITPIIFILINTILDVLIKQKTITPSGFTNMIQFLGSPIIAVGIGLVIAIYGLAGKLNKEEVINEMEKGIK
SAGIIILVTGGGGALGMVLRDSGTGDYIAKLIAGSHMPVVLIPFIIASLVRLIQGSGTVAMITAASITAPIVAASNVNPI
LAALGACMGSLLFSYFNDSYFWVVNRSLGIKDAKEQIKVWSVTTTIAWAVGLIELIILSFIL

Sequences:

>Translated_462_residues
MGNTVAGNQMILGLVVGISILVFLILKTKIHTFLALIIAAATTGLVGGMPPNKIIDSISKGFGGTLGSIGIIIGFGVMMG
QIFEVSGAAERMARTFIKFLGKKREELALAITGFIVSIPIFCDSGFIILAPLAKAISKKTKKSVVSLGVALGLGLVITHS
LVPPTPGPVGVAGIFGVSVGNFILWGIPLAIPMVIAGMIYGKYIGKKIYQIPGDKEDEWIRTEYQEPVYDFEHEEDNKEL
PSTFMAFAPIITPIIFILINTILDVLIKQKTITPSGFTNMIQFLGSPIIAVGIGLVIAIYGLAGKLNKEEVINEMEKGIK
SAGIIILVTGGGGALGMVLRDSGTGDYIAKLIAGSHMPVVLIPFIIASLVRLIQGSGTVAMITAASITAPIVAASNVNPI
LAALGACMGSLLFSYFNDSYFWVVNRSLGIKDAKEQIKVWSVTTTIAWAVGLIELIILSFIL
>Mature_461_residues
GNTVAGNQMILGLVVGISILVFLILKTKIHTFLALIIAAATTGLVGGMPPNKIIDSISKGFGGTLGSIGIIIGFGVMMGQ
IFEVSGAAERMARTFIKFLGKKREELALAITGFIVSIPIFCDSGFIILAPLAKAISKKTKKSVVSLGVALGLGLVITHSL
VPPTPGPVGVAGIFGVSVGNFILWGIPLAIPMVIAGMIYGKYIGKKIYQIPGDKEDEWIRTEYQEPVYDFEHEEDNKELP
STFMAFAPIITPIIFILINTILDVLIKQKTITPSGFTNMIQFLGSPIIAVGIGLVIAIYGLAGKLNKEEVINEMEKGIKS
AGIIILVTGGGGALGMVLRDSGTGDYIAKLIAGSHMPVVLIPFIIASLVRLIQGSGTVAMITAASITAPIVAASNVNPIL
AALGACMGSLLFSYFNDSYFWVVNRSLGIKDAKEQIKVWSVTTTIAWAVGLIELIILSFIL

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI1790716, Length=450, Percent_Identity=32.2222222222222, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI48994935, Length=450, Percent_Identity=32.8888888888889, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789097, Length=434, Percent_Identity=33.8709677419355, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI1788707, Length=458, Percent_Identity=31.0043668122271, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI48994939, Length=451, Percent_Identity=31.4855875831486, Blast_Score=206, Evalue=4e-54,
Organism=Escherichia coli, GI1790776, Length=460, Percent_Identity=31.304347826087, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI2367370, Length=454, Percent_Identity=32.8193832599119, Blast_Score=201, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 48833; Mature: 48702

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GNTVAGNQMILGLVVGISILVFLILKTKIHTFLALIIAAATTGLVGGMPPNKIIDSISK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH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EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]