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The map label for this gene is resE [H]

Identifier: 226949223

GI number: 226949223

Start: 2195633

End: 2197096

Strand: Reverse

Name: resE [H]

Synonym: CLM_2142

Alternate gene names: 226949223

Gene position: 2197096-2195633 (Counterclockwise)

Preceding gene: 226949224

Following gene: 226949222

Centisome position: 52.87

GC content: 26.16

Gene sequence:

>1464_bases
ATGATGGAAAAAGCATCCTTAAAAACACAAACTATAAGTACTTTTTTATTAATTATATTTTTAAGTATAGTATGTACAAT
AGCTACTCTAGGAACTTATTTATTTACTATGTATTTTGGGAAAAATCCTATGCTAGAGCCAAATAACCATTATCAAAAAC
AGTCTGATAAAATTCAGCAGTTTATAGTTAGTAAGGGAGAAAATATATTAGAGGATAAAAATAGATTAGAACTTGAAAAT
TTAGTTCCCCAAAAAGGTATTGGGTATCAAATTACAGATCTAGAGGGTAAAATTATATATGGAAATGAAAAAGAAAGAAT
AATAAAGAATAAAAAACAATTGATAGAATCAATAAATAAAACAGATATTGATAATCTTGATAGAGCTAGTGTTTTTGGAT
CAAAGGTTAAAAGGTATATACCTATATTGGATAGTGATTCCAATGTGAAAGGCGTTGCTATAATTAAATACAATATTGAG
ACAAGTGTGAAGAAAGATAAAAATGAAAAAATAGTTCATGTATTTCAAGTATTTTTACCATTCTCACCTTTTGTATATAT
AATTATTTTTACACTTATTTTTACAAGAAAATTAATTAAAAGTATTCAACAGCCTATAAATGAAATAATAGCTGCTTCAA
ATAAGATAAAAGAAAAGGACTTAGACTTTGAAATAAATTATAAAAGTAATAATGAGTTAGGAAAATTAGTTTCTTCTTTT
GAAGAGATGAAAAATGCTTTAAAAGAATCACTAAATAAACAATGGATTATGGAAGAAGATAGAAAAGAAATGATAAAAGC
CATAGCTCATGATTTGAAAACTCCTATTACTGTTATTCAAGGACATGTAGAGGTACTAATGGAAGGGGGAATTAAAGATC
CCATTAGAGTAGAAAAATATTTAAATATTATAAAAGCTAATACAGAGAGAATGGGAAGGCTTATTTCAGATATGAATCTC
ACATCAGAAATAGAGAATAAAAACTTTGGTTTAGCTCCTGTAAAGGTAGATATAATTGAATTCTTAGAAAAAAAACAACA
GGATTATAAAGTGCTATGTAAGGACAAAAATATAGAATTTAAATTGTTTTTAGAAAAGAATTTTGATTTAAACAAGGAAT
TTTCTATAGATGCTGAAAGACTAGAGCAAATACTAGATAATATAATATCTAATGCCATAAGGTATACACCTGATGGAAAA
TCCATAATTACTAAAGTAAAAATACATAATAATATTATAAAATTTATTGTGGAAGACGAAGGAACAGGTTTTAGTGATAA
GGAATTATGCTATATTTTTGAAAAATTCTATAGGGGTGATAGTTCAAGATCTAAAGAGAAAGGTCACTCTGGATTGGGAA
TGTACATTGTAAGAATTTTAGTAGAAAAGCATAATGGTTGGATTGTAGCAGAAAATAAAGAAAAAGGCGGAGCTAGAATA
GAATTTGTTATAAAAGAAATATGA

Upstream 100 bases:

>100_bases
AGCATATAAAAAAGATAAGAGCAAAGTTTATAAAAATAAGTGTATCTCTTAATCATATAGCTACGGTATGGGGAGTAGGT
TATAGATGGGAGAGAAAAAA

Downstream 100 bases:

>100_bases
AGATGTTGAATATTTTGGTATAGAACCAGGTCTTTGAGTTAACTTGTACAAGCTGTAGATGATTTTTTTTATTTTTTTAT
TTAATGTGTAAATACGTATA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MMEKASLKTQTISTFLLIIFLSIVCTIATLGTYLFTMYFGKNPMLEPNNHYQKQSDKIQQFIVSKGENILEDKNRLELEN
LVPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINKTDIDNLDRASVFGSKVKRYIPILDSDSNVKGVAIIKYNIE
TSVKKDKNEKIVHVFQVFLPFSPFVYIIIFTLIFTRKLIKSIQQPINEIIAASNKIKEKDLDFEINYKSNNELGKLVSSF
EEMKNALKESLNKQWIMEEDRKEMIKAIAHDLKTPITVIQGHVEVLMEGGIKDPIRVEKYLNIIKANTERMGRLISDMNL
TSEIENKNFGLAPVKVDIIEFLEKKQQDYKVLCKDKNIEFKLFLEKNFDLNKEFSIDAERLEQILDNIISNAIRYTPDGK
SIITKVKIHNNIIKFIVEDEGTGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARI
EFVIKEI

Sequences:

>Translated_487_residues
MMEKASLKTQTISTFLLIIFLSIVCTIATLGTYLFTMYFGKNPMLEPNNHYQKQSDKIQQFIVSKGENILEDKNRLELEN
LVPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINKTDIDNLDRASVFGSKVKRYIPILDSDSNVKGVAIIKYNIE
TSVKKDKNEKIVHVFQVFLPFSPFVYIIIFTLIFTRKLIKSIQQPINEIIAASNKIKEKDLDFEINYKSNNELGKLVSSF
EEMKNALKESLNKQWIMEEDRKEMIKAIAHDLKTPITVIQGHVEVLMEGGIKDPIRVEKYLNIIKANTERMGRLISDMNL
TSEIENKNFGLAPVKVDIIEFLEKKQQDYKVLCKDKNIEFKLFLEKNFDLNKEFSIDAERLEQILDNIISNAIRYTPDGK
SIITKVKIHNNIIKFIVEDEGTGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARI
EFVIKEI
>Mature_487_residues
MMEKASLKTQTISTFLLIIFLSIVCTIATLGTYLFTMYFGKNPMLEPNNHYQKQSDKIQQFIVSKGENILEDKNRLELEN
LVPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINKTDIDNLDRASVFGSKVKRYIPILDSDSNVKGVAIIKYNIE
TSVKKDKNEKIVHVFQVFLPFSPFVYIIIFTLIFTRKLIKSIQQPINEIIAASNKIKEKDLDFEINYKSNNELGKLVSSF
EEMKNALKESLNKQWIMEEDRKEMIKAIAHDLKTPITVIQGHVEVLMEGGIKDPIRVEKYLNIIKANTERMGRLISDMNL
TSEIENKNFGLAPVKVDIIEFLEKKQQDYKVLCKDKNIEFKLFLEKNFDLNKEFSIDAERLEQILDNIISNAIRYTPDGK
SIITKVKIHNNIIKFIVEDEGTGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARI
EFVIKEI

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=285, Percent_Identity=25.6140350877193, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786783, Length=297, Percent_Identity=26.9360269360269, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=30.3030303030303, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787894, Length=282, Percent_Identity=25.177304964539, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790346, Length=246, Percent_Identity=26.8292682926829, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=25.3968253968254, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790861, Length=251, Percent_Identity=27.4900398406374, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI48994928, Length=226, Percent_Identity=27.8761061946903, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=23.6947791164659, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87082128, Length=310, Percent_Identity=23.8709677419355, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1789149, Length=348, Percent_Identity=22.4137931034483, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=26.6968325791855, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790551, Length=298, Percent_Identity=23.1543624161074, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=316, Percent_Identity=22.7848101265823, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081816, Length=326, Percent_Identity=22.3926380368098, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=245, Percent_Identity=27.3469387755102, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789403, Length=295, Percent_Identity=23.3898305084746, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787374, Length=318, Percent_Identity=21.6981132075472, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56260; Mature: 56260

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEKASLKTQTISTFLLIIFLSIVCTIATLGTYLFTMYFGKNPMLEPNNHYQKQSDKIQQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
FIVSKGENILEDKNRLELENLVPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINK
HHHHCCCHHHHCCHHHHHHHCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCC
TDIDNLDRASVFGSKVKRYIPILDSDSNVKGVAIIKYNIETSVKKDKNEKIVHVFQVFLP
CCCCCCHHHHHHHHHHHHHCCEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHC
FSPFVYIIIFTLIFTRKLIKSIQQPINEIIAASNKIKEKDLDFEINYKSNNELGKLVSSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHH
EEMKNALKESLNKQWIMEEDRKEMIKAIAHDLKTPITVIQGHVEVLMEGGIKDPIRVEKY
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LNIIKANTERMGRLISDMNLTSEIENKNFGLAPVKVDIIEFLEKKQQDYKVLCKDKNIEF
HHHHHCCHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEE
KLFLEKNFDLNKEFSIDAERLEQILDNIISNAIRYTPDGKSIITKVKIHNNIIKFIVEDE
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCHHHEEEEEECCCEEEEEEECC
GTGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARI
CCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEE
EFVIKEI
EEEEECC
>Mature Secondary Structure
MMEKASLKTQTISTFLLIIFLSIVCTIATLGTYLFTMYFGKNPMLEPNNHYQKQSDKIQQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
FIVSKGENILEDKNRLELENLVPQKGIGYQITDLEGKIIYGNEKERIIKNKKQLIESINK
HHHHCCCHHHHCCHHHHHHHCCCCCCCCEEEECCCCEEEECCCHHHHHHHHHHHHHHCCC
TDIDNLDRASVFGSKVKRYIPILDSDSNVKGVAIIKYNIETSVKKDKNEKIVHVFQVFLP
CCCCCCHHHHHHHHHHHHHCCEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHC
FSPFVYIIIFTLIFTRKLIKSIQQPINEIIAASNKIKEKDLDFEINYKSNNELGKLVSSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHH
EEMKNALKESLNKQWIMEEDRKEMIKAIAHDLKTPITVIQGHVEVLMEGGIKDPIRVEKY
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHH
LNIIKANTERMGRLISDMNLTSEIENKNFGLAPVKVDIIEFLEKKQQDYKVLCKDKNIEF
HHHHHCCHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCEE
KLFLEKNFDLNKEFSIDAERLEQILDNIISNAIRYTPDGKSIITKVKIHNNIIKFIVEDE
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCHHHEEEEEECCCEEEEEEECC
GTGFSDKELCYIFEKFYRGDSSRSKEKGHSGLGMYIVRILVEKHNGWIVAENKEKGGARI
CCCCCCHHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEE
EFVIKEI
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]