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The map label for this gene is pfkB [H]

Identifier: 226949009

GI number: 226949009

Start: 1972570

End: 1973475

Strand: Direct

Name: pfkB [H]

Synonym: CLM_1923

Alternate gene names: 226949009

Gene position: 1972570-1973475 (Clockwise)

Preceding gene: 226949008

Following gene: 226949011

Centisome position: 47.47

GC content: 29.25

Gene sequence:

>906_bases
ATGATTTATACTATTACTTTTAATCCAGCTTTAGACTATGTAGTTAAGGTAGAGGATTTTAAAACAGGTAATTTAAATAG
AACAAGCTATGAAAAGATTTATGCAGGAGGGAAGGGAATAAATGTTTCCATAGTCTTAAATAATTTAGATGTAGAAAATA
TAGCTTTAGGTTATATAGCTGGTTTTACAGGGGATGAAATAGAAAGAAGAGTTAGATCCTTTGGATGTAAAACGGATTTT
ATTAGATTAAAAAATGGAATGTCTAGAATAAATGTAAAGCTAAAATCAAAGGAAGAATCAGAGATTAATGGAACAGGACC
TTCTATAAATACTGAGGACTTAGATGAATTGTTTAATAAACTAGATAATCTAAAAGAAGGAGATTTTTTGATACTTGCGG
GAAGCATTCCTAAAACTCTTCCAGAGAATATATATGAAACTATAATGGAAAGACTTAAAGATAAAAATATAAAATTTGTA
GTGGATGCCACTGGAGAACTTTTACTAAAGGTATTAAAATATAAGCCATTTTTAATTAAGCCTAATCACCATGAGTTGTC
AGAATTGTTTGATGTAGAAATTAAAAATGAAGAAGAAATAATAGGTTATAGTAGAAAATTACAGACGATGGGAGCAGAAA
ATGTTCTTATTTCTATGGCAGGAGATGGAGCAATATTTATTTCATCTAAAGGAGAAGTAATAAAAAGTAGTGTACCTAAA
GGAGTTTTAAAAAATTCTGTAGGAGCAGGAGATTCTATGGTAGCAGGTTTTATATTAGGATATTTAAAAAATAATAATCT
GGAAAATGCATTTAAAATGGGTTTAGCTACCGGTAGTGCTAGTGCCTTTTCGGAAGGATTAGCTACCAAAGAAAAAGTAG
AAGAGACATTAAAACAAATATTATAA

Upstream 100 bases:

>100_bases
TCTGTAACTTTTGGTGATATTAATAAAGCCACCATAATTACAACAAGAATTTTAGATATAAATACAAAGATTTAACAAGA
ATAGTGGAGGTGATAATATA

Downstream 100 bases:

>100_bases
AGTAAAACTGATTTATTTAAATATAAAATTAGTTAGGCATATTATAATGGATGAAGAATTTAAAAACGGTTTAATAAATT
AATAAAAATCCCACAATAAA

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIYTITFNPALDYVVKVEDFKTGNLNRTSYEKIYAGGKGINVSIVLNNLDVENIALGYIAGFTGDEIERRVRSFGCKTDF
IRLKNGMSRINVKLKSKEESEINGTGPSINTEDLDELFNKLDNLKEGDFLILAGSIPKTLPENIYETIMERLKDKNIKFV
VDATGELLLKVLKYKPFLIKPNHHELSELFDVEIKNEEEIIGYSRKLQTMGAENVLISMAGDGAIFISSKGEVIKSSVPK
GVLKNSVGAGDSMVAGFILGYLKNNNLENAFKMGLATGSASAFSEGLATKEKVEETLKQIL

Sequences:

>Translated_301_residues
MIYTITFNPALDYVVKVEDFKTGNLNRTSYEKIYAGGKGINVSIVLNNLDVENIALGYIAGFTGDEIERRVRSFGCKTDF
IRLKNGMSRINVKLKSKEESEINGTGPSINTEDLDELFNKLDNLKEGDFLILAGSIPKTLPENIYETIMERLKDKNIKFV
VDATGELLLKVLKYKPFLIKPNHHELSELFDVEIKNEEEIIGYSRKLQTMGAENVLISMAGDGAIFISSKGEVIKSSVPK
GVLKNSVGAGDSMVAGFILGYLKNNNLENAFKMGLATGSASAFSEGLATKEKVEETLKQIL
>Mature_301_residues
MIYTITFNPALDYVVKVEDFKTGNLNRTSYEKIYAGGKGINVSIVLNNLDVENIALGYIAGFTGDEIERRVRSFGCKTDF
IRLKNGMSRINVKLKSKEESEINGTGPSINTEDLDELFNKLDNLKEGDFLILAGSIPKTLPENIYETIMERLKDKNIKFV
VDATGELLLKVLKYKPFLIKPNHHELSELFDVEIKNEEEIIGYSRKLQTMGAENVLISMAGDGAIFISSKGEVIKSSVPK
GVLKNSVGAGDSMVAGFILGYLKNNNLENAFKMGLATGSASAFSEGLATKEKVEETLKQIL

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=274, Percent_Identity=29.9270072992701, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788017, Length=291, Percent_Identity=26.4604810996564, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 33221; Mature: 33221

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYTITFNPALDYVVKVEDFKTGNLNRTSYEKIYAGGKGINVSIVLNNLDVENIALGYIA
CEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEEECCCHHHEEEEEEE
GFTGDEIERRVRSFGCKTDFIRLKNGMSRINVKLKSKEESEINGTGPSINTEDLDELFNK
CCCCHHHHHHHHHCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
LDNLKEGDFLILAGSIPKTLPENIYETIMERLKDKNIKFVVDATGELLLKVLKYKPFLIK
HHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCEEEC
PNHHELSELFDVEIKNEEEIIGYSRKLQTMGAENVLISMAGDGAIFISSKGEVIKSSVPK
CCHHHHHHHHCCEECCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCHHHHHCCH
GVLKNSVGAGDSMVAGFILGYLKNNNLENAFKMGLATGSASAFSEGLATKEKVEETLKQI
HHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHH
L
C
>Mature Secondary Structure
MIYTITFNPALDYVVKVEDFKTGNLNRTSYEKIYAGGKGINVSIVLNNLDVENIALGYIA
CEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEEECCCHHHEEEEEEE
GFTGDEIERRVRSFGCKTDFIRLKNGMSRINVKLKSKEESEINGTGPSINTEDLDELFNK
CCCCHHHHHHHHHCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
LDNLKEGDFLILAGSIPKTLPENIYETIMERLKDKNIKFVVDATGELLLKVLKYKPFLIK
HHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHCCCEEEC
PNHHELSELFDVEIKNEEEIIGYSRKLQTMGAENVLISMAGDGAIFISSKGEVIKSSVPK
CCHHHHHHHHCCEECCCHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCHHHHHCCH
GVLKNSVGAGDSMVAGFILGYLKNNNLENAFKMGLATGSASAFSEGLATKEKVEETLKQI
HHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHH
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]