Click here to switch to the map view.

The map label for this gene is bdhA [H]

Identifier: 226948686

GI number: 226948686

Start: 1644288

End: 1645451

Strand: Direct

Name: bdhA [H]

Synonym: CLM_1584

Alternate gene names: 226948686

Gene position: 1644288-1645451 (Clockwise)

Preceding gene: 226948684

Following gene: 226948687

Centisome position: 39.57

GC content: 31.44

Gene sequence:

>1164_bases
ATGTTAAATTTTAATTATTCTATACCAACAAAAATTTTTTTCGGTAAAAACCAAATAAGTGTTTTAGGAGAGCAAATAAA
AAAATATGGATCAAGGGTATTGCTTACTTATGGTGGAGGAAGTATAAAAAAGAATGGAGTATATGATAAAGTTATAAAAA
TTTTAAAGAGCAATAATATAGAATTTGTTGAGCTTTCAGGAATAGATCCTAATCCAAGAGTAACTAGTGTAAGGGAAGGA
GTAAAATTATGCAAAGAAAATAATATAGATTTCATATTAGCAGTAGGAGGAGGAAGTACTATAGATTGCTCAAAGGTAAT
AGCTGCATCATATTATTATGAAGGAGATCCTTGGGATATAGTAACTAAAAAAGTTAAAATAAATAAGGCATTACCTATAG
GAAGTATATTAACACTAGCTGCCACTGGCTCAGAAATGGATGCTGGAGCAGTAATTAGTAATATGGATACTAATGAAAAA
ATAGGAGTAGGACATCCTTCTATGGCCCCTAAATTTTCCATATTAGATCCAGAATATACTTTTACAGTGCCCAAAAATCA
AACAGCAGCAGGAACTGCAGATATAATGAGTCATATATTTGAAGCCTATTTCAGCAAGACAAAGGAAGCTTATATTCAAA
ATAGAATGGCAGAGGCTATTTTAAAAACTTGTATAGAGTATGGGAAGGTAGCCATAAAGGAGCCAGAAAATTATGAAGCT
AGGGCTAATCTTATGTGGGCGTCTAGTTTAGCTATAAATGGATTATTAAGTTATGGTAAATCAGAACCTTGGAGTGTACA
CCCTATGGAACATGAATTGAGTGCTTTTTATGATATAACTCATGGTGTGGGGTTAGCTATATTAACCCCAAATTGGATGA
AATATGTTTTGAGCGATGAAAATGTAAATGATTTTTATGAATATGGAGTAAATGTTTGGGATATAAATCCAGAAGAAAGC
AAATATGAAGTAGCACAAAAGGCTATAGAAAAAACTCGAGAATATTTTATAGAATTAGGAATTCCAGCCACATTAAAAGA
AGTAGGTATAGGAGAAGAAAAACTAGAACAAATGGCAGAGGCTGCTACAAGAAATGGAACTTTAGATGGTTTTAAACCTT
TAAGTACTGAAGATGTTTTAAATATATATAAATTATCACTTTAA

Upstream 100 bases:

>100_bases
GTTTTAGGTAATGACATAGAGACATAAGTAATGTTGTAGTATATGCTTTCAAACTATTTCTTAAAATAATATTTAATTAA
AGATAATGGGAGGAGAAATA

Downstream 100 bases:

>100_bases
CTTTAATATAAAATATATACCTATGTTAGGTGATTTTTGATTTTAAATATAGTTTCATTAGAAATAATTATCATTGAAAT
TTAAAATTATTTATTTAAGA

Product: NADH-dependent butanol dehydrogenase

Products: NA

Alternate protein names: BDH I [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNIEFVELSGIDPNPRVTSVREG
VKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDIVTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEK
IGVGHPSMAPKFSILDPEYTFTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIEYGKVAIKEPENYEA
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDENVNDFYEYGVNVWDINPEES
KYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAEAATRNGTLDGFKPLSTEDVLNIYKLSL

Sequences:

>Translated_387_residues
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNIEFVELSGIDPNPRVTSVREG
VKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDIVTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEK
IGVGHPSMAPKFSILDPEYTFTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIEYGKVAIKEPENYEA
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDENVNDFYEYGVNVWDINPEES
KYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAEAATRNGTLDGFKPLSTEDVLNIYKLSL
>Mature_387_residues
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNIEFVELSGIDPNPRVTSVREG
VKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDIVTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEK
IGVGHPSMAPKFSILDPEYTFTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIEYGKVAIKEPENYEA
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDENVNDFYEYGVNVWDINPEES
KYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAEAATRNGTLDGFKPLSTEDVLNIYKLSL

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=423, Percent_Identity=21.0401891252955, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1789386, Length=354, Percent_Identity=44.6327683615819, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI48994951, Length=388, Percent_Identity=28.8659793814433, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789163, Length=383, Percent_Identity=25.5874673629243, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1787493, Length=376, Percent_Identity=24.2021276595745, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082107, Length=388, Percent_Identity=24.4845360824742, Blast_Score=98, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17537053, Length=395, Percent_Identity=24.0506329113924, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321181, Length=366, Percent_Identity=27.8688524590164, Blast_Score=124, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 42887; Mature: 42887

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNI
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCC
EFVELSGIDPNPRVTSVREGVKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDI
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHEEECCCCHHH
VTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEKIGVGHPSMAPKFSILDPEYT
EEEEEEECCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEE
FTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIEYGKVAIKEPENYEA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCH
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDE
HEEEEEHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCEEEEECCHHHEEEECCC
NVNDFYEYGVNVWDINPEESKYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAE
CCHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCHHHHHHHHH
AATRNGTLDGFKPLSTEDVLNIYKLSL
HHHCCCCCCCCCCCCHHHHHHHHEECC
>Mature Secondary Structure
MLNFNYSIPTKIFFGKNQISVLGEQIKKYGSRVLLTYGGGSIKKNGVYDKVIKILKSNNI
CCCCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCC
EFVELSGIDPNPRVTSVREGVKLCKENNIDFILAVGGGSTIDCSKVIAASYYYEGDPWDI
CEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHEEECCCCHHH
VTKKVKINKALPIGSILTLAATGSEMDAGAVISNMDTNEKIGVGHPSMAPKFSILDPEYT
EEEEEEECCCCCCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCEEEEECCCEE
FTVPKNQTAAGTADIMSHIFEAYFSKTKEAYIQNRMAEAILKTCIEYGKVAIKEPENYEA
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCH
RANLMWASSLAINGLLSYGKSEPWSVHPMEHELSAFYDITHGVGLAILTPNWMKYVLSDE
HEEEEEHHHHHHHHHHHCCCCCCCEECCHHHHHHHHHHHHCCCEEEEECCHHHEEEECCC
NVNDFYEYGVNVWDINPEESKYEVAQKAIEKTREYFIELGIPATLKEVGIGEEKLEQMAE
CCHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHCCCCHHHHHHHHH
AATRNGTLDGFKPLSTEDVLNIYKLSL
HHHCCCCCCCCCCCCHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1385386; 11466286; 1809209 [H]