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The map label for this gene is uppS [H]

Identifier: 226948608

GI number: 226948608

Start: 1559900

End: 1560547

Strand: Direct

Name: uppS [H]

Synonym: CLM_1503

Alternate gene names: 226948608

Gene position: 1559900-1560547 (Clockwise)

Preceding gene: 226948606

Following gene: 226948609

Centisome position: 37.54

GC content: 30.86

Gene sequence:

>648_bases
ATGAGAGTACCAAATCATATTGGTATAATTCCAGATGGAAATAGAAGATGGGCTAACAATAAAGGAATGGAAAAACAGTG
TGGATATAAATTTGGGCTAAATCCTGGACTTATATTATTTAGGCTTTGTAAAGCCGTAGGTATAAATGAGATTACATATT
ATGGTTTTACTACAGATAACAATAAAAGACCTAAAGTACAAAGGGAATCTTTTACCAAAGCCTGTGTTGAAGCAGTAGAA
ATGCTATGTAATGAAGATGCTTCTCTACTTGTAGTAGGAAATACAGAATCATCAATGTTTCCAAAGGAACTACTTCCCTA
TACTAAGGAAAGAAAAGTATTTAAAAAAGGGGGAATAAAGGTAAATTTTCTTGTGAATTATGGTTGGGAGTGGGATCTTC
AAGCTTTAGAAAATAATAAGTTAAGTAGTAGAAATAAAATAAATAAACATATAAAGTCTACAGATATATCAAGGGTAGAT
TTAATAATAAGGTGGGGCGGCAGAAGAAGGTTAAGTGGATTTTTACCAATACAATCAGTATATTCTGATTTTTATATAAT
AGAAGATTACTGGCCAGATTTTAAATCAGAACATTTATATGAAGCATTAGAATGGTATGATAAGCAAGATATAACTTTAG
GTGGCTAA

Upstream 100 bases:

>100_bases
TCCAATACCGTTTTCTTGAAATAGTTCCATATGTTTAAAAACACCATTATTGTACATAATAATGGTAATTAAAAAAATAA
GATTTAAAGGAGGAGAATTT

Downstream 100 bases:

>100_bases
ACGCAATAAAATTGAATTTATCCATCAATTTTAATATATTAGTATTACAGCACATAATAGTATATAAGATAATCTATTAT
AAGAGCAACACTATTAAATA

Product: undecaprenyl pyrophosphate synthetase-like protein

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MRVPNHIGIIPDGNRRWANNKGMEKQCGYKFGLNPGLILFRLCKAVGINEITYYGFTTDNNKRPKVQRESFTKACVEAVE
MLCNEDASLLVVGNTESSMFPKELLPYTKERKVFKKGGIKVNFLVNYGWEWDLQALENNKLSSRNKINKHIKSTDISRVD
LIIRWGGRRRLSGFLPIQSVYSDFYIIEDYWPDFKSEHLYEALEWYDKQDITLGG

Sequences:

>Translated_215_residues
MRVPNHIGIIPDGNRRWANNKGMEKQCGYKFGLNPGLILFRLCKAVGINEITYYGFTTDNNKRPKVQRESFTKACVEAVE
MLCNEDASLLVVGNTESSMFPKELLPYTKERKVFKKGGIKVNFLVNYGWEWDLQALENNKLSSRNKINKHIKSTDISRVD
LIIRWGGRRRLSGFLPIQSVYSDFYIIEDYWPDFKSEHLYEALEWYDKQDITLGG
>Mature_215_residues
MRVPNHIGIIPDGNRRWANNKGMEKQCGYKFGLNPGLILFRLCKAVGINEITYYGFTTDNNKRPKVQRESFTKACVEAVE
MLCNEDASLLVVGNTESSMFPKELLPYTKERKVFKKGGIKVNFLVNYGWEWDLQALENNKLSSRNKINKHIKSTDISRVD
LIIRWGGRRRLSGFLPIQSVYSDFYIIEDYWPDFKSEHLYEALEWYDKQDITLGG

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580738, Length=223, Percent_Identity=28.2511210762332, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI45580742, Length=223, Percent_Identity=28.2511210762332, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1786371, Length=228, Percent_Identity=28.5087719298246, Blast_Score=99, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319474, Length=210, Percent_Identity=24.7619047619048, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 24971; Mature: 24971

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVPNHIGIIPDGNRRWANNKGMEKQCGYKFGLNPGLILFRLCKAVGINEITYYGFTTDN
CCCCCCEEEEECCCCCCCCCCCCHHHCCEEECCCHHHHHHHHHHHCCCCCEEEEEEECCC
NKRPKVQRESFTKACVEAVEMLCNEDASLLVVGNTESSMFPKELLPYTKERKVFKKGGIK
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHCCCE
VNFLVNYGWEWDLQALENNKLSSRNKINKHIKSTDISRVDLIIRWGGRRRLSGFLPIQSV
EEEEEECCCCEEHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHH
YSDFYIIEDYWPDFKSEHLYEALEWYDKQDITLGG
HCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MRVPNHIGIIPDGNRRWANNKGMEKQCGYKFGLNPGLILFRLCKAVGINEITYYGFTTDN
CCCCCCEEEEECCCCCCCCCCCCHHHCCEEECCCHHHHHHHHHHHCCCCCEEEEEEECCC
NKRPKVQRESFTKACVEAVEMLCNEDASLLVVGNTESSMFPKELLPYTKERKVFKKGGIK
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHCCCE
VNFLVNYGWEWDLQALENNKLSSRNKINKHIKSTDISRVDLIIRWGGRRRLSGFLPIQSV
EEEEEECCCCEEHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHH
YSDFYIIEDYWPDFKSEHLYEALEWYDKQDITLGG
HCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]