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The map label for this gene is mtnA [H]

Identifier: 226948535

GI number: 226948535

Start: 1482590

End: 1483639

Strand: Direct

Name: mtnA [H]

Synonym: CLM_1427

Alternate gene names: 226948535

Gene position: 1482590-1483639 (Clockwise)

Preceding gene: 226948534

Following gene: 226948536

Centisome position: 35.68

GC content: 32.1

Gene sequence:

>1050_bases
ATGGCAGAGTTATTAGCTATAAAATGGGATGATAATAGAGATAAGTTAATACTTTTAGACCAAACAATATTACCAAATAA
AATTGAATATATAGAATACGATACTGCAGAAGGTGTATACGATTCCATAAAGGATATGATAGTTAGAGGAGCTCCGGCTA
TAGGAGTTACAGCGGCTTATGGTCTATATTTTGCAGCAAAAGTAGCACCAGAAGATAATTTTGAGAACTTCTTTAAATAT
CTAAAAGAAAAATCATCATATTTAGACTCAAGTAGACCAACAGCTGTAAATTTATCTTGGGCCTTAAAGGTTATGGAAAG
TAAAGCTTTAGAAAATAAAGATAAAGATGTTAAAGAAATAAAGAGTATATTAAGAGAAGAAGCTAAAAGGATTCATGAAG
AAGATATAGAAATATGCAAAGCTATAGGAGAAAATCTTATAACTTTATTAAAGGATGGAGTGGGAATATTAACTCATTGT
AATGCTGGGCAACTTGCTACATCTAAATACGGAACAGCTACATCTCCTATGTATCTTGCAAAGGAAAAGGGCTGGAATTT
TAAAGTTTATTCAGATGAAACTAGACCAAGGCTTCAAGGGTCCACTTTAACAGCTTTAGAGTTATATGAGGCAGGAATAG
ATGTAACTACTATAACAGATAATATGGCAGCTATGGTTATGTCTCAAGGCAAAATTGATGCGGTAATAGTAGGATGTGAT
AGAATAGCAGCTAATGGAGATACCGCTAATAAAATAGGAACTATGGGAGTTTCAATTTTGGCTAAATATTTTGGAATACC
AATGTATATTGCTGCACCAACTCCAAGTATAGATATGAATACAAAAACAGGAAAAGATATACCAATAGAAGAGAGAAATT
CAGAAGAAATTACTAGTAGATTTGGTGTTTGGACAGCCCCAAAAGGTGTAAAAGTTTATAATCCAGGATTTGATGTTACA
CCACATGAAAATATAACTGCCATTGTTACAGAAAAGGGTATAGTATATCCTCCTTTTAAAGAAAATTTAAAGAAACTTTT
TGAAAAATAA

Upstream 100 bases:

>100_bases
CTTAAAAATAACTGTTTTATATAATAAGATTTCCAAATAAAAAAGGATTAGTAAAGAAGAAATAAGGTAAATAAAAGAAA
AGTGAAGGGGAGAATTAAAA

Downstream 100 bases:

>100_bases
GAGGTTAGAAAGGAGCTAAAATAATGGTAGAACTTCTTAATATAAAAAATATAAAAAAGTCCTTTTCAGATGTTCAAGTA
TTACATGAAATAAATAATTG

Product: methylthioribose-1-phosphate isomerase

Products: NA

Alternate protein names: M1Pi; MTR-1-P isomerase; S-methyl-5-thioribose-1-phosphate isomerase [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDNFENFFKY
LKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEIKSILREEAKRIHEEDIEICKAIGENLITLLKDGVGILTHC
NAGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCD
RIAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDMNTKTGKDIPIEERNSEEITSRFGVWTAPKGVKVYNPGFDVT
PHENITAIVTEKGIVYPPFKENLKKLFEK

Sequences:

>Translated_349_residues
MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDNFENFFKY
LKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEIKSILREEAKRIHEEDIEICKAIGENLITLLKDGVGILTHC
NAGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCD
RIAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDMNTKTGKDIPIEERNSEEITSRFGVWTAPKGVKVYNPGFDVT
PHENITAIVTEKGIVYPPFKENLKKLFEK
>Mature_348_residues
AELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAYGLYFAAKVAPEDNFENFFKYL
KEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEIKSILREEAKRIHEEDIEICKAIGENLITLLKDGVGILTHCN
AGQLATSKYGTATSPMYLAKEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCDR
IAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDMNTKTGKDIPIEERNSEEITSRFGVWTAPKGVKVYNPGFDVTP
HENITAIVTEKGIVYPPFKENLKKLFEK

Specific function: Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) [H]

COG id: COG0182

COG function: function code J; Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily [H]

Homologues:

Organism=Homo sapiens, GI72534748, Length=347, Percent_Identity=37.7521613832853, Blast_Score=218, Evalue=5e-57,
Organism=Homo sapiens, GI23943880, Length=336, Percent_Identity=35.4166666666667, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17557462, Length=326, Percent_Identity=36.8098159509202, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17557123, Length=275, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325375, Length=381, Percent_Identity=36.4829396325459, Blast_Score=185, Evalue=9e-48,
Organism=Drosophila melanogaster, GI21357667, Length=366, Percent_Identity=38.2513661202186, Blast_Score=220, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24651647, Length=366, Percent_Identity=38.2513661202186, Blast_Score=220, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000649
- InterPro:   IPR005251
- InterPro:   IPR011559 [H]

Pfam domain/function: PF01008 IF-2B [H]

EC number: =5.3.1.23 [H]

Molecular weight: Translated: 38704; Mature: 38573

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAY
CCCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
GLYFAAKVAPEDNFENFFKYLKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEI
HHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHH
KSILREEAKRIHEEDIEICKAIGENLITLLKDGVGILTHCNAGQLATSKYGTATSPMYLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCCEEEE
KEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCD
ECCCCEEEEECCCCCCCCCCCEEHHHHHHHCCCCEEEECCHHHHHHHCCCCEEEEEEECC
RIAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDMNTKTGKDIPIEERNSEEITSR
CEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHH
FGVWTAPKGVKVYNPGFDVTPHENITAIVTEKGIVYPPFKENLKKLFEK
CCCEECCCCCEEECCCCCCCCCCCEEEEEECCCEECCCHHHHHHHHHCC
>Mature Secondary Structure 
AELLAIKWDDNRDKLILLDQTILPNKIEYIEYDTAEGVYDSIKDMIVRGAPAIGVTAAY
CCEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHH
GLYFAAKVAPEDNFENFFKYLKEKSSYLDSSRPTAVNLSWALKVMESKALENKDKDVKEI
HHHHEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCCCHHHHH
KSILREEAKRIHEEDIEICKAIGENLITLLKDGVGILTHCNAGQLATSKYGTATSPMYLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEECCCCCCCCCCEEEE
KEKGWNFKVYSDETRPRLQGSTLTALELYEAGIDVTTITDNMAAMVMSQGKIDAVIVGCD
ECCCCEEEEECCCCCCCCCCCEEHHHHHHHCCCCEEEECCHHHHHHHCCCCEEEEEEECC
RIAANGDTANKIGTMGVSILAKYFGIPMYIAAPTPSIDMNTKTGKDIPIEERNSEEITSR
CEECCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHH
FGVWTAPKGVKVYNPGFDVTPHENITAIVTEKGIVYPPFKENLKKLFEK
CCCEECCCCCEEECCCCCCCCCCCEEEEEECCCEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA