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The map label for this gene is patH [H]

Identifier: 226948448

GI number: 226948448

Start: 1392461

End: 1393285

Strand: Direct

Name: patH [H]

Synonym: CLM_1332

Alternate gene names: 226948448

Gene position: 1392461-1393285 (Clockwise)

Preceding gene: 226948447

Following gene: 226948449

Centisome position: 33.51

GC content: 26.91

Gene sequence:

>825_bases
TTGAATATAAAAAAGTTTAAAAAAATATTTTTAAGTATGTCATTAGTTGTAGCTTTAGGAGTAGCATTAACAGCATGTGC
TCAGAAGAATAAACAAATAAAGGAAAATAAAAATACAATAAAAATAGGAACTTCAGGACAGTACTATCCTTTTACTTTTA
TAGATAAAGATAGTAATAAAGTCCAAGGATTTGAAATAGATATTTGGGAAGAAATAGGTAAAAGAACAGGTTATAAACCA
GAATTTAAGGTAGCAGATTGGACAGGCATTATGGGAATGCTAGATACAGGTAAAATAGATACTGTAGCCAATGAGATAAC
TGTAACAGATAAGAAAAAAGAAAAATATTATTTTTCAAAACCTTATGTTTATTCAGGAGTACAGTTAGCTACTAAAAAAG
GAAATAATAATATAAAATCTTTAAAGGATTTAGAGGGAAAAACTGTAGCTACGCAGGTAGGAACTAATTATTCTAAATCC
ATAGAAGATTATAATAATAAGAATAAAGGAGAAGATATAAAAACAAAACAATATAATAGTTTTTCAGGTATGTTCCAAGA
TGTGGATTTGGGTAGAGTTGATGCTTTAATAGAGGATAAATTAGCCTGCCTTGTAAATATAAAAAAATCAGGATTAAATT
TACAGTTGGCCGGTGAACCTATAGAAGAGATGGAAAATGCATATCCTTTTGTAAAGAAGGATGAAAATAAAGAAAAAATA
GAAAAAATAAATAAAGCTTTAGATGATATGAAAAATGATGGAACTTTACAAAATATATCTAAAAAATGGTTTGGAGAAAA
TGTTACAGAAAAGAGTAAAAAATAA

Upstream 100 bases:

>100_bases
GTAATGGTAGAGTTATTTAATTTTATGCAAAAATTATTAGAAAGAAAAATAGGAAAAGCTTATTAAAATTTAATATTAAT
AGTATTAGGAGGATATAGAA

Downstream 100 bases:

>100_bases
TCTATTTGATTAAATTTAAATATTTTTAATATAAAATTTTAAAGATATTAATATAAAATCCATAGTTACAAATAATAAAA
TAAAAAACAGTGGTGATTAT

Product: polar amino acid uptake ABC transporter amino acid-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MNIKKFKKIFLSMSLVVALGVALTACAQKNKQIKENKNTIKIGTSGQYYPFTFIDKDSNKVQGFEIDIWEEIGKRTGYKP
EFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSKPYVYSGVQLATKKGNNNIKSLKDLEGKTVATQVGTNYSKS
IEDYNNKNKGEDIKTKQYNSFSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK

Sequences:

>Translated_274_residues
MNIKKFKKIFLSMSLVVALGVALTACAQKNKQIKENKNTIKIGTSGQYYPFTFIDKDSNKVQGFEIDIWEEIGKRTGYKP
EFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSKPYVYSGVQLATKKGNNNIKSLKDLEGKTVATQVGTNYSKS
IEDYNNKNKGEDIKTKQYNSFSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK
>Mature_274_residues
MNIKKFKKIFLSMSLVVALGVALTACAQKNKQIKENKNTIKIGTSGQYYPFTFIDKDSNKVQGFEIDIWEEIGKRTGYKP
EFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSKPYVYSGVQLATKKGNNNIKSLKDLEGKTVATQVGTNYSKS
IEDYNNKNKGEDIKTKQYNSFSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK

Specific function: Probably part of a binding-protein-dependent transport system for an amino acid [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=261, Percent_Identity=36.3984674329502, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787031, Length=263, Percent_Identity=32.319391634981, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788649, Length=271, Percent_Identity=28.0442804428044, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787085, Length=230, Percent_Identity=28.2608695652174, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787088, Length=255, Percent_Identity=26.2745098039216, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788648, Length=237, Percent_Identity=25.3164556962025, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 31016; Mature: 31016

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01034 GLYCOSYL_HYDROL_F16

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKKFKKIFLSMSLVVALGVALTACAQKNKQIKENKNTIKIGTSGQYYPFTFIDKDSNK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCC
VQGFEIDIWEEIGKRTGYKPEFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSK
CCCEEEHHHHHHHHHCCCCCCEEECCHHHHHHCCCCCCHHHHHCEEEECCCCCCCEEECC
PYVYSGVQLATKKGNNNIKSLKDLEGKTVATQVGTNYSKSIEDYNNKNKGEDIKTKQYNS
CEEECCEEEEEECCCCCHHHHHHCCCCEEEEHHCCCHHHHHHHHCCCCCCCCCCCCCCCC
FSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
HHCCHHCCCCHHHHHHHHHHHHHEEEECCCCCEEEECCCCHHHHHHCCCCCCCCCCHHHH
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK
HHHHHHHHHHCCCCCHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MNIKKFKKIFLSMSLVVALGVALTACAQKNKQIKENKNTIKIGTSGQYYPFTFIDKDSNK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCC
VQGFEIDIWEEIGKRTGYKPEFKVADWTGIMGMLDTGKIDTVANEITVTDKKKEKYYFSK
CCCEEEHHHHHHHHHCCCCCCEEECCHHHHHHCCCCCCHHHHHCEEEECCCCCCCEEECC
PYVYSGVQLATKKGNNNIKSLKDLEGKTVATQVGTNYSKSIEDYNNKNKGEDIKTKQYNS
CEEECCEEEEEECCCCCHHHHHHCCCCEEEEHHCCCHHHHHHHHCCCCCCCCCCCCCCCC
FSGMFQDVDLGRVDALIEDKLACLVNIKKSGLNLQLAGEPIEEMENAYPFVKKDENKEKI
HHCCHHCCCCHHHHHHHHHHHHHEEEECCCCCEEEECCCCHHHHHHCCCCCCCCCCHHHH
EKINKALDDMKNDGTLQNISKKWFGENVTEKSKK
HHHHHHHHHHCCCCCHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA